Table of Contents
Int. J. Mol. Sci., Volume 16, Issue 7 (July 2015) , Pages 14291-16709
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Cover Story The cover picture shows a schematic representation of the formation of a disulfide combinatorial [...] Read more. The cover picture shows a schematic representation of the formation of a disulfide combinatorial library. Simple, basic building blocks, from which are formed more complex compounds, are situated in the middle of the picture. Aromatic units of these blocks are represented by hexagons and thiol moieties are represented by yellow dots. Due to the dynamism of the disulfide bond, this bond is able to be broken up and formed again. Consequently, under certain specifically chosen conditions, the mixing of compounds with such bonds contributes to the formation of a dynamic library of disulfide compounds, to which we can include 2-, 3-, and even 4-membered macrocycle rings and catenanes, as presented in the picture. The composition of the library is changeable and can be controlled using both chemical and physical stimuli. View the article.