Int. J. Mol. Sci., Volume 16, Issue 6 (June 2015) – 136 articles , Pages 11834-14290
Cover Story: ER-mitochondrial contact sites play important roles during autophagy. In particular, they provide platforms for the assembly of the early autophagy machinery, and regulate autophagosome signaling and assembly through calcium signaling and lipid exchange. Parallel siRNA screens for factors involved in ER/mitochondrial dynamics and connectivity revealed that different regulators of calcium exchange contribute to autophagy (SigmaR1) and mitophagy (IP3Rs) responses in RPE1 cells. The contributions these and other candidates to autophagy and mitophagy are explored. View the article.
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.