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International Journal of Molecular Sciences, Volume 16, Issue 12

December 2015 - 163 articles

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Articles (163)

  • Article
  • Open Access
56 Citations
10,869 Views
14 Pages

18 December 2015

Anoectochilus roxburghii (Wall.) Lindl. (Orchidaceae) is an endangered medicinal plant in China, also called “King Medicine”. Due to lacking of sufficient nutrients in dust-like seeds, orchid species depend on mycorrhizal fungi for seed germination i...

  • Article
  • Open Access
11 Citations
9,251 Views
19 Pages

18 December 2015

MicroRNAs represent ~22 nt long endogenous small RNA molecules that have been experimentally shown to regulate gene expression post-transcriptionally. One main interest in miRNA research is the investigation of their functional roles, which can typic...

  • Review
  • Open Access
355 Citations
35,845 Views
28 Pages

Applications of Micro-Fourier Transform Infrared Spectroscopy (FTIR) in the Geological Sciences—A Review

  • Yanyan Chen,
  • Caineng Zou,
  • Maria Mastalerz,
  • Suyun Hu,
  • Carley Gasaway and
  • Xiaowan Tao

18 December 2015

Fourier transform infrared spectroscopy (FTIR) can provide crucial information on the molecular structure of organic and inorganic components and has been used extensively for chemical characterization of geological samples in the past few decades. I...

  • Article
  • Open Access
49 Citations
7,396 Views
18 Pages

Short- and Long-Term Effects of Prenatal Exposure to Iron Oxide Nanoparticles: Influence of Surface Charge and Dose on Developmental and Reproductive Toxicity

  • Kristin R. Di Bona,
  • Yaolin Xu,
  • Marquita Gray,
  • Douglas Fair,
  • Hunter Hayles,
  • Luckie Milad,
  • Alex Montes,
  • Jennifer Sherwood,
  • Yuping Bao and
  • Jane F. Rasco

18 December 2015

Iron oxide nanoparticles (NPs) are commonly utilized for biomedical, industrial, and commercial applications due to their unique properties and potential biocompatibility. However, little is known about how exposure to iron oxide NPs may affect susce...

  • Review
  • Open Access
211 Citations
28,054 Views
40 Pages

Oxidative Stress and Inflammation in Hepatic Diseases: Therapeutic Possibilities of N-Acetylcysteine

  • Kívia Queiroz De Andrade,
  • Fabiana Andréa Moura,
  • John Marques Dos Santos,
  • Orlando Roberto Pimentel De Araújo,
  • Juliana Célia De Farias Santos and
  • Marília Oliveira Fonseca Goulart

18 December 2015

Liver disease is highly prevalent in the world. Oxidative stress (OS) and inflammation are the most important pathogenetic events in liver diseases, regardless the different etiology and natural course. N-acetyl-l-cysteine (the active form) (NAC) is...

  • Review
  • Open Access
12 Citations
7,951 Views
12 Pages

Human Anti-Oxidation Protein A1M—A Potential Kidney Protection Agent in Peptide Receptor Radionuclide Therapy

  • Jonas Ahlstedt,
  • Thuy A. Tran,
  • Sven-Erik Strand,
  • Magnus Gram and
  • Bo Åkerström

18 December 2015

Peptide receptor radionuclide therapy (PRRT) has been in clinical use for 15 years to treat metastatic neuroendocrine tumors. PRRT is limited by reabsorption and retention of the administered radiolabeled somatostatin analogues in the proximal tubule...

  • Review
  • Open Access
133 Citations
17,360 Views
21 Pages

FLIP the Switch: Regulation of Apoptosis and Necroptosis by cFLIP

  • Yuichi Tsuchiya,
  • Osamu Nakabayashi and
  • Hiroyasu Nakano

18 December 2015

cFLIP (cellular FLICE-like inhibitory protein) is structurally related to caspase-8 but lacks proteolytic activity due to multiple amino acid substitutions of catalytically important residues. cFLIP protein is evolutionarily conserved and expressed a...

  • Article
  • Open Access
24 Citations
12,395 Views
14 Pages

Biochemical Characterization of An Arginine-Specific Alkaline Trypsin from Bacillus licheniformis

  • Jin-Song Gong,
  • Wei Li,
  • Dan-Dan Zhang,
  • Min-Feng Xie,
  • Biao Yang,
  • Rong-Xian Zhang,
  • Heng Li,
  • Zhen-Ming Lu,
  • Zheng-Hong Xu and
  • Jin-Song Shi

17 December 2015

In the present study, we isolated a trypsin-producing strain DMN6 from the leather waste and identified it as Bacillus licheniformis through a two-step screening strategy. The trypsin activity was increased up to 140 from 20 U/mL through culture opti...

  • Review
  • Open Access
83 Citations
12,752 Views
16 Pages

17 December 2015

This review analyzes current studies of the therapeutic effects of Phoenix dactylifera, or date palm fruit, on the physiologic system. Specifically, we sought to summarize the effects of its application in preventing cell damage, improving cancer the...

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Int. J. Mol. Sci. - ISSN 1422-0067