Molecules, Volume 30, Issue 6
2025 March-2 - 207 articles
Cover Story: HOF•CH3CN is a unique tool for transferring oxygen atoms to many molecules. Some of these transformations have already been performed in the past with various orthodox reagents, the difference being speed, temperature, and yield, all in favor of the complex of the hypofluorous acid acetonitrile. More importantly, however, it can transfer oxygen to many sites that were previously considered impossible to oxidize. Such transformations open many new synthetic possibilities. The fact that at the end of the reaction, the solvent is aqueous acetonitrile, which can be easily recycled, and water-diluted HF—which can be quenched with any base, alumina, and the like—makes it a green reaction. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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