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Molecules, Volume 27, Issue 19

2022 October-1 - 637 articles

Cover Story: This study developed Eri-DMSN@FSP, UV-responsive erianin-loaded dendritic mesoporous silica nanoparticles. The first step in this study was to synthesize dendritic mesoporous silica nanoparticles (DMSNs) via soft templating. Subsequently, the preliminary nanoparticles were calcined at 600 ℃ for 5 h to obtain DMSNs. The DMSNs were then modified with APTES as well as PFDTES, and grafted with the prepared SP-COOH, resulting in DMSN@FSP. The next step was to load erianin into the pores of the nanoparticles to obtain Eri-DMSN@FSP. Finally, DMSNs, DMSN@FSP, and Eri-DMSN@FSP were physicochemically characterized, and their therapeutic effects were explored in a psoriasis cell model. View this paper
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Articles (637)

  • Review
  • Open Access
50 Citations
7,465 Views
22 Pages

A Review of Bioactive Compounds and Antioxidant Activity Properties of Piper Species

  • Nono Carsono,
  • Sefren Geiner Tumilaar,
  • Dikdik Kurnia,
  • Diding Latipudin and
  • Mieke Hermiawati Satari

10 October 2022

Antioxidants are compounds that are able to inhibit the negative effects that come from free radicals. The phenomenon of imbalanced antioxidant production and the accumulation of free radicals in cells and tissues can cause oxidative stress. Excessiv...

  • Feature Paper
  • Review
  • Open Access
9 Citations
6,327 Views
29 Pages

10 October 2022

The enteric nervous system (ENS) is a part of the autonomic nervous system that intrinsically innervates the gastrointestinal (GI) tract. Whereas enteric neurons have been deeply studied, the enteric glial cells (EGCs) have received less attention. H...

  • Communication
  • Open Access
20 Citations
3,662 Views
12 Pages

Fabrication of Orange Fluorescent Boron-Doped Graphene Quantum Dots for Al3+ Ion Detection

  • Weitao Li,
  • Luoman Zhang,
  • Ningjia Jiang,
  • Yongqian Chen,
  • Jie Gao,
  • Jihang Zhang,
  • Baoshuo Yang and
  • Jialin Liu

10 October 2022

Aluminum is a kind of metal that we often encounter. It can also be absorbed by the human body invisibly and will affect our bodies to a certain extent, e.g., by causing symptoms associated with Alzheimer’s disease. Therefore, the detection of...

  • Article
  • Open Access
25 Citations
4,190 Views
25 Pages

Luminescent Carbon Dots from Wet Olive Pomace: Structural Insights, Photophysical Properties and Cytotoxicity

  • Diogo A. Sousa,
  • Luís F. V. Ferreira,
  • Alexander A. Fedorov,
  • Ana M. B. do Rego,
  • Ana M. Ferraria,
  • Adriana B. Cruz,
  • Mário N. Berberan-Santos and
  • José V. Prata

10 October 2022

Carbon nanomaterials endowed with significant luminescence have been synthesized for the first time from an abundant, highly localized waste, the wet pomace (WP), a semi-solid by-product of industrial olive oil production. Synthetic efforts were unde...

  • Article
  • Open Access
41 Citations
6,251 Views
12 Pages

Synthesis and Characterization of Novel Hydrazone Derivatives of Isonicotinic Hydrazide and Their Evaluation for Antibacterial and Cytotoxic Potential

  • Muhammad Abdullah Shah,
  • Ala Uddin,
  • Muhammad Raza Shah,
  • Imdad Ali,
  • Riaz Ullah,
  • Peer Abdul Hannan and
  • Hidayat Hussain

10 October 2022

Hydrazones are active compounds having an azomethine –NHN=CH group and are widely studied owing to their ease of preparation and diverse pharmacological benefits. Novel isonicotinic hydrazone derivatives of vanillin aldehyde and salicyl aldehyd...

  • Review
  • Open Access
45 Citations
8,077 Views
40 Pages

Thiazolidin-2,4-Dione Scaffold: An Insight into Recent Advances as Antimicrobial, Antioxidant, and Hypoglycemic Agents

  • Harsh Kumar,
  • Navidha Aggarwal,
  • Minakshi Gupta Marwaha,
  • Aakash Deep,
  • Hitesh Chopra,
  • Mohammed M. Matin,
  • Arpita Roy,
  • Talha Bin Emran,
  • Yugal Kishore Mohanta and
  • Ahmed Al-Harrasi
  • + 4 authors

10 October 2022

Heterocyclic compounds containing nitrogen and sulfur, especially those in the thiazole family, have generated special interest in terms of their synthetic chemistry, which is attributable to their ubiquitous existence in pharmacologically dynamic na...

  • Article
  • Open Access
9 Citations
3,980 Views
20 Pages

On Some Topological Indices Defined via the Modified Sombor Matrix

  • Xuewu Zuo,
  • Bilal Ahmad Rather,
  • Muhammad Imran and
  • Akbar Ali

10 October 2022

Let G be a simple graph with the vertex set V={v1,…,vn} and denote by dvi the degree of the vertex vi. The modified Sombor index of G is the addition of the numbers (dvi2+dvj2)−1/2 over all of the edges vivj of G. The modified Sombor mat...

  • Article
  • Open Access
18 Citations
2,957 Views
15 Pages

Promoting Efficacy and Environmental Safety of Pesticide Synergists via Non-Ionic Gemini Surfactants with Short Fluorocarbon Chains

  • Ruiguo Wang,
  • Xinxin Xu,
  • Xiaodi Shi,
  • Junjie Kou,
  • Hongjian Song,
  • Yuxiu Liu,
  • Jingjing Zhang and
  • Qingmin Wang

10 October 2022

Improving the utilization rate of pesticides is key to achieve a reduction and synergism, and adding appropriate surfactant to pesticide preparation is an effective way to improve pesticide utilization. Fluorinated surfactants have excellent surface...

  • Article
  • Open Access
3 Citations
2,499 Views
17 Pages

Syntheses of New Multisubstituted 1-Acyloxyindole Compounds

  • Ye Eun Kim,
  • Yoo Jin Lim,
  • Chorong Kim,
  • Yu Ra Jeong,
  • Hyunsung Cho and
  • Sang Hyup Lee

10 October 2022

The syntheses of novel 1-acyloxyindole compounds 1 and the investigations on reaction pathways are presented. Nitro ketoester substrate 2, obtained in a two-step synthetic process, underwent reduction, intramolecular addition, nucleophilic 1,5-additi...

  • Article
  • Open Access
4 Citations
2,569 Views
14 Pages

Exploring 2-Tetradecanoylimino-3-aryl-4-methyl-1,3-thiazolines Derivatives as Alkaline Phosphatase Inhibitors: Biochemical Evaluation and Computational Analysis

  • Aftab Ahmed,
  • Sajid-ur Rehman,
  • Syeda Abida Ejaz,
  • Aamer Saeed,
  • Rabail Ujan,
  • Pervaiz Ali Channar,
  • Khalida Mahar,
  • Reshma Sahito,
  • Sarah M. Albogami and
  • Gaber El-Saber Batiha
  • + 3 authors

10 October 2022

The current study focused on the laboratory approach in conjunction with computational methods for the synthesis and bioactivity assessment of unique 2-tetradecanoylimino-3-aryl-4-methyl-1,3-thiazolines (2a–2k). Processes included cyclizing 1-a...

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Molecules - ISSN 1420-3049