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Molecules, Volume 27, Issue 12

June-2 2022 - 316 articles

Cover Story: Advanced carbon microelectrodes based on carbon nanotubes (CNTs) are being developed for the in vivo detection of neurotransmitters such as dopamine (DA). We use molecular dynamics simulations to investigate the adsorbed structures and surface diffusion dynamics of DA and related species on CNTs of varying curvature and helicity and in the groove between two aligned CNTs. We find that diffusion depends upon curvature and correlates with the vertical placement of the adsorbate’s moieties, its tilt angle, its orientation along the CNT axis, and the number of waters in its first hydration shell, all of which will influence its effective hydrodynamic radius. In addition, DA diffuses into and remains in the groove between the pair of aligned CNTs, enhancing diffusivity along the CNT axis. View this paper
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Articles (316)

  • Article
  • Open Access
2 Citations
2,050 Views
19 Pages

Molybdenum Disulphide Precipitation in Jet Reactors: Introduction of Kinetics Model for Computational Fluid Dynamics Calculations

  • Michał Wojtalik,
  • Krzysztof Wojtas,
  • Weronika Gołębiowska,
  • Maria Jarząbek,
  • Wojciech Orciuch and
  • Łukasz Makowski

20 June 2022

In our previous work, we used the population balance method to develop a molybdenum disulphide kinetics model consisting of a set of differential equations and constants formulated to express the kinetics of complex chemical reactions leading to moly...

  • Article
  • Open Access
8 Citations
2,319 Views
9 Pages

Graphene Oxide-Sensitized Surface Plasmon Resonance Biosensor of Porcine Reproductive and Respiratory Syndrome Virus

  • Xuemei Liu,
  • Chao Xu,
  • Chunyu Fu,
  • Dongfang Xia,
  • Fuchao Wang,
  • Hongzong Yin and
  • Jun Peng

20 June 2022

Biosensor analysis based on the surface plasmon resonance (SPR) phenomenon enables label-free, highly sensitive analyte detection without prior sample purification or processing. However, potential applications of SPR biosensors in virus detection in...

  • Article
  • Open Access
40 Citations
4,994 Views
20 Pages

Simultaneous Removal of Heavy Metals (Cu, Cd, Cr, Ni, Zn and Pb) from Aqueous Solutions Using Thermally Treated Romanian Zeolitic Volcanic Tuff

  • Marin Senila,
  • Emilia Neag,
  • Oana Cadar,
  • Emoke Dalma Kovacs,
  • Ioan Aschilean and
  • Melinda Haydee Kovacs

20 June 2022

Increased concentrations of heavy metals in the environment are of public health concern, their removal from waters receiving considerable interest. The aim of this paper was to study the simultaneous adsorption of heavy metals (Cu, Cd, Cr, Ni, Zn an...

  • Review
  • Open Access
18 Citations
5,673 Views
26 Pages

Theragnostic Applications of Mammal and Plant-Derived Extracellular Vesicles: Latest Findings, Current Technologies, and Prospects

  • Nada Basheir Ali,
  • Ahmad Faizal Abdull Razis,
  • Der Jiun Ooi,
  • Kim Wei Chan,
  • Norsharina Ismail and
  • Jhi Biau Foo

20 June 2022

The way cells communicate is not fully understood. However, it is well-known that extracellular vesicles (EVs) are involved. Researchers initially thought that EVs were used by cells to remove cellular waste. It is now clear that EVs function as sign...

  • Article
  • Open Access
18 Citations
3,783 Views
19 Pages

Preparation, Characterization, and In Vitro Release of Curcumin-Loaded IRMOF-10 Nanoparticles and Investigation of Their Pro-Apoptotic Effects on Human Hepatoma HepG2 Cells

  • Dongge Yin,
  • Xueling Hu,
  • Mengru Cai,
  • Kaixin Wang,
  • Hulinyue Peng,
  • Jie Bai,
  • Yvchen Xv,
  • Tingting Fu,
  • Xiaoxv Dong and
  • Jian Ni
  • + 1 author

20 June 2022

Curcumin (CUR) has a bright future in the treatment of cancer as a natural active ingredient with great potential. However, curcumin has a low solubility, which limits its clinical application. In this study, IRMOF-10 was created by the direct additi...

  • Review
  • Open Access
26 Citations
5,958 Views
19 Pages

Biological Activities of Organic Extracts of the Genus Aristolochia: A Review from 2005 to 2021

  • Martín A. Lerma-Herrera,
  • Lidia Beiza-Granados,
  • Alejandra Ochoa-Zarzosa,
  • Joel E. López-Meza,
  • Pedro Navarro-Santos,
  • Rafael Herrera-Bucio,
  • Judit Aviña-Verduzco and
  • Hugo A. García-Gutiérrez

20 June 2022

Different ethnomedicinal studies have investigated the relationship between various phytochemicals as well as organic extracts and their bioactive aspects. Studies on biological effects are attributed to secondary metabolites such as alkaloids, pheno...

  • Article
  • Open Access
13 Citations
2,854 Views
12 Pages

Facile Synthesis of Porous Ag Crystals as SERS Sensor for Detection of Five Methamphetamine Analogs

  • Yazhou Qin,
  • Fan Mo,
  • Sen Yao,
  • Yuanzhao Wu,
  • Yingsheng He and
  • Weixuan Yao

20 June 2022

Porous noble metal nanomaterials have attracted extensive attention due to their high specific surface area and surface plasmon resonance effect. However, it is difficult to form porous structures due to the high mobility and low reduction potential...

  • Article
  • Open Access
4 Citations
2,127 Views
7 Pages

20 June 2022

Despite the enormous efforts made to develop other fusion inhibitors for HIV, the enfuvirtide (known as T20) peptide is the only approved HIV-1 inhibitory drug so far. Investigating the role of potential residues of the T20 peptide’s conformati...

  • Article
  • Open Access
10 Citations
3,691 Views
16 Pages

A Metabolomic Analysis of Cirrhotic Ascites

  • Diren Beyoğlu,
  • Cedric Simillion,
  • Federico Storni,
  • Andrea De Gottardi and
  • Jeffrey R. Idle

20 June 2022

Ascites is a common complication of decompensated liver cirrhosis, and yet relatively little is known about its biochemical composition. We conducted two metabolomic investigations, comparing the profile of ascites from 33 cirrhotic patients and post...

  • Article
  • Open Access
5 Citations
2,737 Views
20 Pages

Synthesis and Antileukemia Activity Evaluation of Benzophenanthridine Alkaloid Derivatives

  • Yaling Tang,
  • Xinglian Xu,
  • Jiang Li,
  • Lulu Deng and
  • Shuzhen Mu

19 June 2022

Thirty-three benzophenanthridine alkaloid derivatives (1a–1u and 2a–2l) were synthesized, and their cytotoxic activities against two leukemia cell lines (Jurkat Clone E6-1 and THP-1) were evaluated in vitro using a Cell Counting Kit-8 (CC...

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Molecules - ISSN 1420-3049