Synthesis of Bioactive Compounds
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 27760
Special Issue Editor
Special Issue Information
Dear Colleagues,
In the past few decades, the emergence of new highly pathogenic strains of viruses and microorganisms such as SARS-CoV-2, drug-resistant tuberculosis and malaria (i.e., superbugs), has presented challenges that require urgent response. Effective treatment of cancer is another important and unresolved problem. Tumors develop through genetic and epigenetic changes that modify fundamental cellular programs for growth and proliferation, followed by the natural selection of reprogrammed cells that best adapt to the constant fight against human immunity and chemotherapy drugs.
To address these issues, a number of breakthrough synthetic methodologies need to be developed which enable the efficient assembly of new molecules and make it possible to achieve the high variability of substituents necessary for studying structure–biological activity relationships.
This Special Issue aims to gather scientific articles devoted to the synthesis and study of the activity of previously unknown compounds, as well as fully synthetic papers that describe new effective approaches to known biologically active compounds, without further evaluation of biological properties.
Dr. Nicolai A. Aksenov
Guest Editor
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Keywords
- biological activity
- nature-derived molecules
- heterocyclic moieties
- aromatic species
- structural diversity
- alkaloids
- organic synthesis
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Related Special Issue
- Synthesis of Bioactive Compounds: Volume II in Molecules (12 articles)