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Molecules, Volume 26, Issue 2

January-2 2021 - 268 articles

Cover Story: This brief review focuses on reactive oxygen species (ROS) generation for photodynamic therapy. The specialty of this topic is embodied in the fact that ROS comes from the introduction of aggregation-induced emission luminogens (AIEgens) into the design of photosensitizers (PSs), or AIE–PSs. Based on the nature of the generated ROS, three kinds of AIE–PSs are classified: (i) ROSs are superoxide anion (O2•−), hydroxyl radical (•OH), peroxide (O22−), and other free radicals through electron transfer; (ii) ROS is singlet oxygen (1O2) through energy transfer; and (iii) both free radical ROS and 1O2 via electron transfer and energy transfer, respectively. This can help readers to understand the significant role played by AIEgens in ROS generation and develop high-performance AIE–PSs. View this paper
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Articles (268)

  • Article
  • Open Access
23 Citations
3,984 Views
16 Pages

Ellagic Acid–Cyclodextrin Complexes for the Treatment of Oral Candidiasis

  • Aline da Graça Sampaio,
  • Aline Vidal Lacerda Gontijo,
  • Gabriela de Morais Gouvêa Lima,
  • Maria Alcionéia Carvalho de Oliveira,
  • Laura Soares Souto Lepesqueur and
  • Cristiane Yumi Koga-Ito

19 January 2021

The increase in the prevalence of fungal infections worldwide and the rise in the occurrence of antifungal resistance suggest that new research to discover antifungal molecules is needed. The aim of this study was to evaluate the potential use of ell...

  • Article
  • Open Access
48 Citations
4,823 Views
15 Pages

Identification of Organic Volatile Markers Associated with Aroma during Maturation of Strawberry Fruits

  • Samuel Macario Padilla-Jiménez,
  • María Valentina Angoa-Pérez,
  • Hortencia Gabriela Mena-Violante,
  • Guadalupe Oyoque-Salcedo,
  • José Luis Montañez-Soto and
  • Ernesto Oregel-Zamudio

19 January 2021

In the present study, organic volatile markers of three strawberry varieties (Albion, Festival and Frontera) during the maturation process were investigated. Forty metabolites associated with aroma in fresh strawberries were monitored during seven st...

  • Article
  • Open Access
7 Citations
3,848 Views
12 Pages

Micellar Casein and Whey Powder Hold a TGF-β Activity and Regulate ID Genes In Vitro

  • Layla Panahipour,
  • Selma Husejnovic,
  • Jila Nasirzade,
  • Stephan Semelmayer and
  • Reinhard Gruber

19 January 2021

Casein and whey being food supplements have been considered to be used in oral health care products. However, the response of oral cells to micellar casein and whey powder remains unclear. Considering that milk contains the growth factor TGF-β,...

  • Article
  • Open Access
19 Citations
5,030 Views
29 Pages

Revealing the Potential Application of EC-Synthetic Retinoid Analogues in Anticancer Therapy

  • Mohamed R. Abdelaal,
  • Sameh H. Soror,
  • Mohamed R. Elnagar and
  • Hesham Haffez

19 January 2021

(1) Background and Aim: All-trans retinoic acid (ATRA) induces differentiation and inhibits growth of many cancer cells. However, resistance develops rapidly prompting the urgent need for new synthetic and potent derivatives. EC19 and EC23 are two sy...

  • Feature Paper
  • Article
  • Open Access
9 Citations
6,006 Views
18 Pages

Characterisation of Elastomers as Food Contact Materials–Part 1: Quantification of Extractable Compounds, Swelling of Elastomers in Food Simulants and Release of Elements

  • Friederike Kühne,
  • Maurus Biedermann,
  • Angela Eicher,
  • Florian Felder,
  • Stefan Sander,
  • Roman Schmidt,
  • Saskia Lehmann,
  • Gregor McCombie,
  • Stefan Merkel and
  • Oliver Kappenstein
  • + 1 author

19 January 2021

Elastomers are not a uniform class of materials but comprise a broad spectrum of chemically different polymers. Sealing gaskets, gloves, teats, conveyor belts and tubing are examples of elastomers being used as food contact materials (FCMs). Ten elas...

  • Review
  • Open Access
76 Citations
10,849 Views
21 Pages

19 January 2021

This review presents applications of spectroscopic methods, infrared and Raman spectroscopies in the studies of the structure of gluten network and gluten proteins (gliadins and glutenins). Both methods provide complimentary information on the second...

  • Article
  • Open Access
7 Citations
3,618 Views
10 Pages

19 January 2021

Pseudouridimycin (PUM) was recently discovered from Streptomyces sp. DSM26212 as a novel bacterial nucleoside analog that competes with UTP for access to the RNA polymerase (RNAP) active site, thereby inhibiting bacterial RNAP by blocking transcripti...

  • Article
  • Open Access
13 Citations
5,452 Views
16 Pages

19 January 2021

The use of arginine deiminase (ADI) for arginine depletion therapy is an attractive anticancer approach. Combination strategies are needed to overcome the resistance of severe types of cancer cells to this monotherapy. In the current study, we report...

  • Article
  • Open Access
9 Citations
3,191 Views
11 Pages

19 January 2021

By incorporating a rhodamine spirolactam structure as the recognition site for Cu2+, two novel probes were synthesized through a connection of rhodamine 6G acylhydrazine and 5-formyl-6-hydroxyl-4-methylcoumarin/2,4-dihydroxybenzaldehyde. In the recog...

  • Article
  • Open Access
5 Citations
4,441 Views
16 Pages

Energetics of Electron Pairs in Electrophilic Aromatic Substitutions

  • Julen Munárriz,
  • Miguel Gallegos,
  • Julia Contreras-García and
  • Ángel Martín Pendás

19 January 2021

The interacting quantum atoms approach (IQA) as applied to the electron-pair exhaustive partition of real space induced by the electron localization function (ELF) is used to examine candidate energetic descriptors to rationalize substituent effects...

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Molecules - ISSN 1420-3049