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Molecules, Volume 26, Issue 1

2021 January-1 - 248 articles

Cover Story: The development of lanthanide-based luminescent probes with a long emission lifetime has the potential to revolutionize imaging-based diagnostic techniques. By a rational design strategy, a novel, water-soluble Eu3+ complex from a cyclen-based ligand bearing 1,3-disubstituted benzo[h]isoquinoline arms was realized. Notably, the steric hindrance of the heteroaromatic chromophore allowed selective and stoichiometry-controlled insertion of two or three antennas on the cyclen platform without any protection strategy. The suitability as a luminescent bioprobe was validated by imaging BMI1 oncomarker in lung carcinoma cells following an established immunofluorescence approach using a conventional epifluorescence microscope equipped with a linear structured illumination module. View this paper
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Articles (248)

  • Article
  • Open Access
5 Citations
3,307 Views
10 Pages

5 January 2021

Potato starch is one of the most important renewable sources for industrial manufacturing of organic compounds. Currently, it is produced from mixed potato varieties that often are harvested from different fields. Meanwhile, tuber starches of various...

  • Article
  • Open Access
3 Citations
4,254 Views
11 Pages

Calcium-Dependent Translocation of S100B Is Facilitated by Neurocalcin Delta

  • Jingyi Zhang,
  • Anuradha Krishnan,
  • Hao Wu and
  • Venkat Venkataraman

5 January 2021

S100B is a calcium-binding protein that governs calcium-mediated responses in a variety of cells—especially neuronal and glial cells. It is also extensively investigated as a potential biomarker for several disease conditions, especially neurod...

  • Review
  • Open Access
573 Citations
30,178 Views
15 Pages

Anti-Inflammatory Action and Mechanisms of Resveratrol

  • Tiantian Meng,
  • Dingfu Xiao,
  • Arowolo Muhammed,
  • Juying Deng,
  • Liang Chen and
  • Jianhua He

5 January 2021

Resveratrol (3,4′,5-trihy- droxystilbene), a natural phytoalexin polyphenol, exhibits anti-oxidant, anti-inflammatory, and anti-carcinogenic properties. This phytoalexin is well-absorbed and rapidly and extensively metabolized in the body. Infl...

  • Article
  • Open Access
16 Citations
4,745 Views
13 Pages

5 January 2021

Isoquinoline alkaloids may have a wide range of pharmacological activities. Some of them have acetylcholinesterase activity inhibition. Nowadays, neurodegenerative disorders such as Alzheimer’s disease have become a serious public health proble...

  • Communication
  • Open Access
3 Citations
3,221 Views
14 Pages

5 January 2021

A simple, mild and efficient method to prepare HSi- or HOSi-telechelic, high-molecular-weight polydimethylsiloxane polymers (to 41,600 g·mol−1) using the one-shot hydrolysis of MHMH is reported; titration of the water allowed for higher...

  • Article
  • Open Access
36 Citations
7,846 Views
21 Pages

Evaluation of Wound-Healing and Antioxidant Effects of Marantodes pumilum (Blume) Kuntze in an Excision Wound Model

  • Shihab Uddin Ahmad,
  • Nor-Ashila Binti Aladdin,
  • Jamia Azdina Jamal,
  • Ahmad Nazrun Shuid and
  • Isa Naina Mohamed

5 January 2021

Marantodes pumilum (MP) is a great source of herbal medicine used traditionally by both men and women for various purposes. MP may have potential wound-healing effects due to its diverse biological properties. An extensive study was conducted in a no...

  • Article
  • Open Access
12 Citations
4,119 Views
17 Pages

Evaluation of the Storage Conditions and Type of Cork Stopper on the Quality of Bottled White Wines

  • María Consuelo Díaz-Maroto,
  • Manuel López Viñas,
  • Lourdes Marchante,
  • María Elena Alañón,
  • Ignacio Javier Díaz-Maroto and
  • María Soledad Pérez-Coello

5 January 2021

The effects of different storage conditions, light exposure, temperature and different commercially available cork stoppers on the phenolic, volatile and sensorial profile of Verdejo wines were studied. Two natural corks of different visual quality a...

  • Article
  • Open Access
1 Citations
3,944 Views
9 Pages

Strawberry Decreases Intraluminal and Intestinal Wall Hydrolysis of Testosterone Undecanoate

  • Atheer Zgair,
  • Yousaf Dawood,
  • Suhaib M. Ibrahem,
  • Jong Bong Lee,
  • Wanshan Feng,
  • Peter M. Fischer and
  • Pavel Gershkovich

5 January 2021

Male hypogonadism is often treated by testosterone (T) replacement therapy such as oral administration of the ester prodrug, testosterone undecanoate (TU). However, the systemic exposure to T following oral TU is very low due to esterase-mediated met...

  • Feature Paper
  • Article
  • Open Access
2,943 Views
15 Pages

5 January 2021

Based on a set of six vector properties, the partial correlation diagram is calculated for a set of 28 S-alkylcysteine diazomethyl- and chloromethyl-ketone derivatives. Those with the greatest antileukemic activity in the same class correspond to hig...

  • Article
  • Open Access
18 Citations
5,440 Views
17 Pages

5 January 2021

The in-vivo monitoring of volatile organic compound (VOC) emissions is a potential non-invasive tool in plant protection, especially in greenhouse cultivation. We studied VOC production from above and belowground organs of the eight parents of the Mu...

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Molecules - ISSN 1420-3049