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Molecules, Volume 23, Issue 2

February 2018 - 290 articles

Cover Story: Biocatalysts able to convert nitroaromatics to aromatic amines are in high demand, yet they are not commonly found in nature and only succeed for a small number of known substrates. The question therefore is “Why”? We show that substrates with large pi systems-bearing electron withdrawing groups, are more likely to form amines. Crucially, nitroreductases accommodate many such substrates. We attribute this to their intertwined architecture that supports very diverse active site shapes and sizes. This segregation of core structure vs. catalytic site, eminently suits the engineering of nitroreductases. View this paper
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Articles (290)

  • Feature Paper
  • Article
  • Open Access
8 Citations
4,274 Views
7 Pages

21 February 2018

Lewis pair polymerization is a powerful method for preparing soluble polymers bearing pendant active vinyl groups by directly polymerizing dissymmetric divinyl polar monomers. Herein, we present a strategy for synthesizing block and brush copolymers...

  • Article
  • Open Access
22 Citations
7,133 Views
14 Pages

21 February 2018

Phenylpropanoids and flavonoids belong to a large group of secondary metabolites, and are considered to have antioxidant activity, which protects the cells against biotic and abiotic stresses. However, the accumulation of phenylpropanoids and flavono...

  • Article
  • Open Access
202 Citations
13,652 Views
13 Pages

Effect of the New Plant Growth Biostimulants Based on Amino Acids on Yield and Grain Quality of Winter Wheat

  • Małgorzata Popko,
  • Izabela Michalak,
  • Radosław Wilk,
  • Mateusz Gramza,
  • Katarzyna Chojnacka and
  • Henryk Górecki

21 February 2018

Field and laboratory experiments were carried out in 2012–2013, aimed at evaluating the influence of new products stimulating plant growth based on amino acids on crop yield, characteristics of grain and content of macro- and micronutrients in winter...

  • Article
  • Open Access
24 Citations
5,772 Views
14 Pages

21 February 2018

Thirty-seven commercial aldehydes containing aliphatic chains and aromatic rings as well as heteroaromatic rings were evaluated for their inhibitory activities against Chinese amaranth (Amaranthus tricolor L.) and barnyardgrass (Echinochloa crus-gall...

  • Article
  • Open Access
30 Citations
5,836 Views
15 Pages

20 February 2018

The volatile compounds in proso millet wine were extracted by headspace solid-phase microextraction (85 μm polyacrylate (PA), 100 μm polydimethylsiloxane (PDMS), 75 μm Carboxen (CAR)/PDMS, and 50/30 μm divinylbenzene (DVB)/CAR/PDMS fibers), and analy...

  • Article
  • Open Access
36 Citations
6,326 Views
11 Pages

Qualitative and Quantitative Phytochemical Analysis of Different Extracts from Thymus algeriensis Aerial Parts

  • Nassima Boutaoui,
  • Lahcene Zaiter,
  • Fadila Benayache,
  • Samir Benayache,
  • Simone Carradori,
  • Stefania Cesa,
  • Anna Maria Giusti,
  • Cristina Campestre,
  • Luigi Menghini and
  • Denise Innosa
  • + 1 author

20 February 2018

This study was performed to evaluate the metabolite recovery from different extraction methods applied to Thymus algeriensis aerial parts. A high-performance liquid chromatographic method using photodiode array detector with gradient elution has been...

  • Article
  • Open Access
8 Citations
5,726 Views
15 Pages

Exploring the Metabolism of (+)-[18F]Flubatine In Vitro and In Vivo: LC-MS/MS Aided Identification of Radiometabolites in a Clinical PET Study

  • Friedrich-Alexander Ludwig,
  • Steffen Fischer,
  • René Smits,
  • Winnie Deuther-Conrad,
  • Alexander Hoepping,
  • Solveig Tiepolt,
  • Marianne Patt,
  • Osama Sabri and
  • Peter Brust

20 February 2018

Both (+)-[18F]flubatine and its enantiomer (−)-[18F]flubatine are radioligands for the neuroimaging of α4β2 nicotinic acetylcholine receptors (nAChRs) by positron emission tomography (PET). In a clinical study in patients with early Alzheimer’s disea...

  • Feature Paper
  • Review
  • Open Access
58 Citations
14,886 Views
21 Pages

Radical Polymerization of Alkyl 2-Cyanoacrylates

  • Cormac Duffy,
  • Per B. Zetterlund and
  • Fawaz Aldabbagh

20 February 2018

Cyanoacrylates (CAs) are well-known fast-setting adhesives, which are sold as liquids in the presence of stabilizers. Rapid anionic polymerization on exposure to surface moisture is responsible for instant adhesion. The more difficult, but synthetica...

  • Article
  • Open Access
15 Citations
4,219 Views
13 Pages

19 February 2018

In this study, two novel boron dipyrromethene-based photosensitizers (BDP3 and BDP6) substituted with three or six trifluoromethyl groups have been synthesized and characterized with various spectroscopic methods, and their photo-physical, photo-chem...

  • Article
  • Open Access
30 Citations
7,364 Views
17 Pages

Nutritional Composition and Antioxidant Properties of the Fruits of a Chinese Wild Passiflora foetida

  • Ya Song,
  • Xiao-Qun Wei,
  • Mei-Ying Li,
  • Xue-Wu Duan,
  • Yuan-Ming Sun,
  • Rui-Li Yang,
  • Xiang-Dong Su,
  • Ri-Ming Huang and
  • Hong Wang

19 February 2018

The aim of this work was to evaluate the main nutrients and their antioxidant properties of a Chinese wild edible fruit, Passiflora foetida, collected from the ecoregion of Hainan province, China. The analytical results revealed that P. foetida fruit...

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Molecules - ISSN 1420-3049