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Molecules, Volume 16, Issue 8

August 2011 - 77 articles

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Articles (77)

  • Article
  • Open Access
52 Citations
8,895 Views
12 Pages

Physico-Chemical Characteristics and Functional Properties of Chitin and Chitosan Produced by Mucor circinelloides Using Yam Bean as Substrate

  • Ana Elizabeth C. Fai,
  • Thayza C.M. Stamford,
  • Thatiana M. Stamford-Arnaud,
  • Petrus D´Amorim Santa-Cruz,
  • Marta C. Freitas da Silva,
  • Galba M. Campos-Takaki and
  • Tânia L.M. Stamford

23 August 2011

Microbiological processes were used for chitin and chitosan production by Mucor circinelloides (UCP 050) grown in yam bean (Pachyrhizus erosus L. Urban) medium. The polysaccharides were extracted by alkali–acid treatment and structural investigations...

  • Article
  • Open Access
71 Citations
14,609 Views
16 Pages

The Growth Suppressing Effects of Girinimbine on Hepg2 Involve Induction of Apoptosis and Cell Cycle Arrest

  • Suvitha Syam,
  • Ahmad Bustamam Abdul,
  • Mohd. Aspollah Sukari,
  • Syam Mohan,
  • Siddig Ibrahim Abdelwahab and
  • Tang Sook Wah

23 August 2011

Murraya koenigii is an edible herb widely used in folk medicine. Here we report that girinimbine, a carbazole alkaloid isolated from this plant, inhibited the growth and induced apoptosis in human hepatocellular carcinoma, HepG2 cells. The MTT and LD...

  • Article
  • Open Access
14 Citations
7,855 Views
12 Pages

Optimized Enzymatic Synthesis of Hesperidin Fatty Acid Esters in a Two-Phase System Containing Ionic Liquid

  • Maria Elisa Melo Branco de Araújo,
  • Fabiano Jares Contesini,
  • Yollanda Edwirges Moreira Franco,
  • Alexandra C.H. Frankland Sawaya,
  • Thiago Grando Alberto,
  • Natália Dalfré and
  • Patrícia de Oliveira Carvalho

23 August 2011

Response surface methodology (RSM) based on a five-level, three-variable central composite design (CCD) was employed for modeling and optimizing the conversion yield of the enzymatic acylation of hesperidin with decanoic acid using immobilized Candid...

  • Communication
  • Open Access
19 Citations
8,551 Views
7 Pages

Azaphenanthrene Alkaloids with Antitumoral Activity from Anaxagorea dolichocarpa Sprague & Sandwith (Annonaceae)

  • Ana Silvia Suassuna Carneiro Lúcio,
  • Jackson Roberto Guedes Da Silva Almeida,
  • José Maria Barbosa-Filho,
  • João Carlos Lima Rodrigues Pita,
  • Marianna Vieira Sobral Castello Branco,
  • Margareth De Fátima Formiga Melo Diniz,
  • Maria De Fátima Agra,
  • Emidio V.L. Da-Cunha,
  • Marcelo Sobral Da Silva and
  • Josean Fechine Tavares

22 August 2011

Phytochemical investigation of Anaxagorea dolichocarpa Sprague & Sandwith led to isolation of three azaphenanthrene alkaloids: eupolauramine, sampangine and imbiline 1. Their chemical structures were established on the basis of spectroscopic data fro...

  • Article
  • Open Access
118 Citations
13,805 Views
11 Pages

22 August 2011

Myristicin (1-allyl-5-methoxy-3,4-methylenedioxybenzene) is an active aromatic compound found in nutmeg (the seed of Myristica fragrans), carrot, basil, cinnamon, and parsley. Myristicin has been known to have anti-cholinergic, antibacterial, and hep...

  • Article
  • Open Access
18 Citations
9,142 Views
10 Pages

Chemical Profile and Biological Potential of Non-Polar Fractions from Centroceras clavulatum (C. Agardh) Montagne (Ceramiales, Rhodophyta)

  • Otávio P. Rocha,
  • Rafael De Felício,
  • Ana Helena B. Rodrigues,
  • Daniela L. Ambrósio,
  • Regina Maria B. Cicarelli,
  • Sérgio De Albuquerque,
  • Maria Claudia M. Young,
  • Nair S. Yokoya and
  • Hosana M. Debonsi

19 August 2011

The present study reports the Gas Chromatography-Mass Spectrometry (GC-MS) evaluation of the hexanes and dichloromethane fractions from extracts of the red alga Centroceras clavulatum (C. Agardh) Montagne. Twenty three compounds were identified, tota...

  • Article
  • Open Access
44 Citations
7,703 Views
10 Pages

Essential Oil Composition of the Different Parts and In Vitro Shoot Culture of Eryngium planum L.

  • Barbara Thiem,
  • Małgorzata Kikowska,
  • Anna Kurowska and
  • Danuta Kalemba

19 August 2011

The essential oils obtained by hydrodistillation from the different parts (inflorescence, stalk leaves, rosette leaves and root) as well as from in vitro shoot culture of Eryngium planum L. were analyzed by GC-FID-MS in respect to their chemical comp...

  • Article
  • Open Access
135 Citations
14,841 Views
13 Pages

Activity and Stability Studies of Verbascoside, a Novel Antioxidant, in Dermo-Cosmetic and Pharmaceutical Topical Formulations

  • Silvia Vertuani,
  • Erika Beghelli,
  • Emanuela Scalambra,
  • Gemma Malisardi,
  • Stefano Copetti,
  • Roberto Dal Toso,
  • Anna Baldisserotto and
  • Stefano Manfredini

18 August 2011

We here report the results of our investigations carried out on verbascoside, a phenylpropanoid glycoside known for its antioxidant, anti-inflammatory and photoprotective actions. Verbascoside was obtained from Buddleia davidii meristematic cells, ob...

  • Article
  • Open Access
5 Citations
6,682 Views
16 Pages

18 August 2011

5-Aryl-7-hydrazino-2-phenylpyrazolo[1,5-c]pyrimidines 1 were used as precursors for the preparation of a new series of 5-aryl-8-phenylpyrazolo[1,5-c]-1,2,4- triazolo[4,3-a]pyrimidines 2. The reactions of 2 with certain electrophilic reagents gave the...

  • Article
  • Open Access
38 Citations
9,829 Views
8 Pages

Alkaloids from Hippeastrum papilio

  • Jean Paulo de Andrade,
  • Strahil Berkov,
  • Francesc Viladomat,
  • Carles Codina,
  • José Angelo S. Zuanazzi and
  • Jaume Bastida

18 August 2011

Galanthamine, an acetylcholinesterase inhibitor marketed as a hydrobromide salt (Razadyne®, Reminyl®) for the treatment of Alzheimer’s disease (AD), is obtained from Amaryllidaceae plants, especially those belonging to the genera Leucojum, Narcissus,...

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Molecules - ISSN 1420-3049