Smart Delivery Systems for Biomolecular Therapeutics

Topic Information

Dear Colleagues,

The rapid advancement of biomolecular therapeutics—including peptides, proteins, nucleic acids, and gene-editing tools—has revolutionized modern medicine, yet their clinical translation remains hindered by challenges in their stability, targeting, and controlled release. Smart delivery systems offer transformative solutions by integrating stimuli-responsive materials, nanotechnology, and bioengineering to protect therapeutic cargo, enhance cellular uptake, and enable precise spatiotemporal control. Innovations such as pH-sensitive nanoparticles, ligand-functionalized carriers, and stimuli-triggered hydrogels are being explored to overcome biological barriers and improve therapeutic indexes. This special topic collection highlights emerging strategies in smart delivery platforms tailored for biomolecular drugs, with emphasis on translational potential, regulatory perspectives, and disease-specific applications including cancer, genetic disorders, and autoimmune diseases. By bridging the gap between molecular innovation and clinical need, smart delivery systems are poised to redefine how we administer complex therapeutics, enabling personalized, effective, and safer treatment modalities. We invite contributions that explore cutting-edge design, preclinical validation, and path-to-market strategies.

Dr. Biana Godin
Dr. Vivek Gupta
Topic Editors

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Biophysica biophysica	1.4	2.3	2021	22.9 Days	CHF 1200	Submit
Current Issues in Molecular Biology cimb	3.0	3.7	1999	17.8 Days	CHF 2200	Submit
International Journal of Molecular Sciences ijms	4.9	9.0	2000	20.5 Days	CHF 2900	Submit
International Journal of Translational Medicine ijtm	-	2.2	2021	25.9 Days	CHF 1000	Submit
Lymphatics lymphatics	-	-	2023	32.3 Days	CHF 1000	Submit
Scientia Pharmaceutica scipharm	2.5	4.6	1930	38.1 Days	CHF 1000	Submit

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