Compounds with Medicinal Value (2nd Volume)

Dear Colleagues,

This Topic is the second volume in a series of publications dedicated to “Compounds with Medicinal Value” (https://www.mdpi.com/topics/Compounds_Medicinal_Value).

In industrialized countries over the last few decades, there has been a significant increase in infectious, cardiovascular, inflammatory and neurodegenerative diseases, as well as different forms of cancer, diabetes, and so on.

Among them, microbial and viral infections and cancer are still the major causes of these issues worldwide due to increased bacterial resistance and the development of resistance to chemotherapeutics. For these reasons, there is an urgent need to design and synthesize new antiviral and antimicrobial agents, particularly those that are active against Gram-negative pathogens, that could be useful in fighting drug resistance. There is also a high demand for new antineoplastic drugs with higher selectivity on tumoral cells able to overcome cancer cells’ resistance with minimal side effects.

Furthermore, some delivery systems have proved effective as antimicrobial, antiviral and anticancer carriers due to targeted drug delivery at the action sites, reduced drug resistance and side effects and an increased therapeutic index.

Recently, many molecules of natural origin and extracts have also proved to be valuable tools.

Potential topics for manuscripts submitted to this Topic include the following:

• The design, synthesis and biological evaluation of anticancer agents;
• The design, synthesis and biological evaluation of antimicrobial agents;
• The design, synthesis and biological evaluation of antiviral agents;
• Molecules of natural origin and extracts with antitumoral, antiviral and antimicrobial properties;
• Delivery systems and nanosystems for targeted anticancer, antimicrobial and antiviral therapies.

Prof. Dr. Maria Stefania Sinicropi
Topic Editor