Research in Vaccine Adjuvants: Innovations and Challenges

Dear Colleagues,

Vaccine adjuvants are critical components in vaccine research and play a key role in improving the immunogenicity and efficacy of vaccines. They work by stimulating the immune system to produce stronger and more durable responses against target pathogens. Despite significant progress in adjuvant research, there are still several hurdles to overcome. These include understanding the mechanisms of adjuvant action, optimizing adjuvant formulations for different vaccine platforms, and addressing potential safety concerns. In addition, the discovery of new adjuvant materials and systems remains a critical area of research to improve vaccine performance.

This Special Issue, "Research in Vaccine Adjuvants: Innovations and Challenges", aims to address these challenges and highlight the latest innovations in adjuvant research. We invite submissions on a variety of topics, including the following:

• New adjuvant materials and systems: exploring novel adjuvants derived from natural sources, synthetic polymers, or biotechnological approaches.
• Mucosal vaccine adjuvants: investigation of adjuvants that enhance the immunogenicity of mucosal vaccines, which are essential for the prevention of infection at mucosal surfaces.
• Mechanisms of adjuvant action: the study of the underlying mechanisms by which adjuvants interact with the immune system to enhance vaccine responses.
• Adjuvant safety and tolerability: evaluating the safety and tolerability of new adjuvants in preclinical and clinical studies.

We welcome original research articles, reviews, and perspectives that contribute to advancing our understanding of vaccine adjuvants. By addressing these topics, we aim to foster new insights and drive innovations in vaccine adjuvant research.

Prof. Dr. Haibo Li
Prof. Dr. Hongwu Sun
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.