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7 Results Found

  • Systematic Review
  • Open Access
8 Citations
5,545 Views
20 Pages

Pregnancy-Related Acute Kidney Injury: Causes and Its Impact on Perinatal Outcomes—A Systematic Review

  • Emmanuel N. Kontomanolis,
  • Ioannis Prokopakis,
  • Antonios Koutras,
  • Emmanouil Andreou and ,
  • Dionysios Metaxas,
  • Gerasimos Boulieris,
  • Eleftherios Zachariou,
  • Ioakeim Sapantzoglou,
  • Dimitrios Papageorgiou and
  • Paraskevas Perros
  • + 11 authors+ 6 authors

26 August 2025

Background: Pregnancy-Related Acute kidney injury (PRAKI) is a critical complication of pregnancy, defined by the sudden deterioration in renal function during gestation or within the initial six weeks postpartum. Pregnancy is thought to increase the...

(This article belongs to the Section Obstetrics & Gynecology)
  • Review
  • Open Access
23 Citations
15,987 Views
22 Pages

6 September 2019

Pregnancy-related acute kidney injury (PR-AKI) is a heterogeneous disorder with multiple aetiologies that can occur at any time throughout pregnancy and the post-partum period. PR-AKI is an important obstetric complication that is associated with sig...

(This article belongs to the Special Issue Kidney Diseases and Kidney Involvement in Pregnancy: the Crossroad of Obstetrics, Nephrology, Urology and Internal Medicine)
  • Editorial
  • Open Access
1 Citations
2,702 Views
3 Pages

20 February 2024

This Special Issue mainly focuses on preeclampsia (PE), haemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome, gestational diabetes mellitus (GDM), foetal growth restriction (FGR), small-for-gestational-age foetuses (SGA), misca...

(This article belongs to the Special Issue Pathogenesis of Pregnancy-Related Complication 2023)
  • Article
  • Open Access
1,314 Views
17 Pages

Indoxyl Sulfate Contributes to Progression of Renal Injury in the Postpartum Period Following Pregnancy-Related Acute Kidney Injury

  • Ashley Griffin,
  • Brittany Berry,
  • Lidia Melaku,
  • Delijah Johnson and ,
  • Perla Guevarra,
  • Leslie A. Shack,
  • Shauna-Kay Spencer,
  • Bindu Nanduri and
  • Kedra Wallace
  • + 4 authors+ 0 author

17 August 2026

Pregnancy-related acute kidney injury (PR-AKI) increases the risk of chronic kidney disease (CKD) in the postpartum period, yet mechanisms driving this transition remain unclear. Uremic toxins, including indoxyl sulfate (IS), are implicated in AKI-to...

(This article belongs to the Special Issue New Insights in Uremic Toxins and Toxin-Related Outcomes in Chronic Kidney Disease)
  • Article
  • Open Access
8 Citations
3,997 Views
9 Pages

Indoxyl Sulfate Administration during Pregnancy Contributes to Renal Injury and Increased Blood–Brain Barrier Permeability

  • Ashley Griffin,
  • Brittany Berry,
  • Shauna-Kay Spencer,
  • Teylor Bowles and
  • Kedra Wallace

Rates of pregnancy-related acute kidney injury (PR-AKI) have increased in the U.S over the past two decades, but how PR-AKI affects the blood–brain barrier (BBB) is understudied. AKI is associated with increased amounts of uremic toxins, like i...

(This article belongs to the Special Issue Pathogenesis of Pregnancy-Related Complication 2023)
  • Article
  • Open Access
2,185 Views
11 Pages

Exploring Pregnancy-Related Acute Kidney Injury: Risk Factors and Maternal Outcomes in High-Risk Women in Mwanza, Tanzania

  • Kahibi Bernard,
  • Fridolin Mujuni,
  • Dismas Matovelo,
  • Edgar Ndaboine and ,
  • Richard Kiritta and
  • Ladius Rudovick
  • + 1 author+ 0 author

Background/Objective: Pregnancy-related acute kidney injury (PRAKI) remains a serious complication, with high rates of maternal morbidity and mortality, particularly in developing countries where delayed diagnosis and treatment are common. This study...

  • Article
  • Open Access
1,494 Views
10 Pages

Assessment of Maternal Hematological Parameters and Kidney and Liver Injury Markers Across Adverse Pregnancy Outcomes: A Cross Sectional Study

  • Ananda Puttaiah,
  • Manjunath S. Somannavar,
  • Mrutyunjaya B. Bellad,
  • Umesh Charantimath and ,
  • M. S. Deepthy,
  • Jeffrey S. A. Stringer and
  • Shivaprasad S. Goudar
  • + 2 authors+ 0 author

24 December 2025

Adverse pregnancy outcomes (APOs) such as prematurity, low birth weight, stillbirth, and birth defects remain significant global health challenges. While many risk factors are known, APOs encompass a wide range of outcomes with diverse, sometimes poo...