You are currently viewing a new version of our website. To view the old version click .

19 Results Found

  • Article
  • Open Access
18 Citations
3,897 Views
16 Pages

The presence of epithelial and connective tissue attachment at the peri-implant–soft tissue region has been demonstrated to provide a biological barrier of the alveolar bone from the oral environment. This barrier can be improved via surface mo...

  • Article
  • Open Access
2 Citations
3,019 Views
14 Pages

Epidermal Growth Factor Is Associated with Loss of Mucosae Sealing and Peri-Implant Mucositis: A Pilot Study

  • José Jorge Schoichet,
  • Carlos Fernando de Almeida Barros Mourão,
  • Edgard de Mello Fonseca,
  • Carlos Ramirez,
  • Ricardo Villas-Boas,
  • Juliana Prazeres,
  • Valquiria Quinelato,
  • Telma Regina Aguiar,
  • Marina Prado and
  • Angelo Cardarelli
  • + 2 authors

27 September 2021

This study aimed to evaluate the correlation between epidermal growth factor (EGF) and receptor (EGFR) levels in different clinical stages of dental implant rehabilitation and trace mucositis development’s biological profile. Thirty-six participants...

  • Article
  • Open Access
31 Citations
6,388 Views
16 Pages

27 November 2017

Mucosal seal formation around dental abutments is critical to the successful integration of dental implants into the human oral cavity. No information exists for how clinically relevant polishing procedures for computer-aided design and computer-aide...

  • Article
  • Open Access
16 Citations
5,790 Views
11 Pages

Characterization of Human Gingival Fibroblasts on Zirconia Surfaces Containing Niobium Oxide

  • Young-Dan Cho,
  • Ji-Cheol Shin,
  • Hyung-In Yoon,
  • Young Ku,
  • Hyun-Mo Ryoo,
  • Dae-Joon Kim,
  • Do-Gyoon Kim and
  • Jung-Suk Han

10 September 2015

It was indicated that tetragonal zirconia polycrystal (TZP) containing yttria (Y2O3) and niobium oxide (Nb2O5) ((Y,Nb)-TZP) could be an adequate dental material to be used at esthetically important sites. The (Y,Nb)-TZP was also proved to possess its...

  • Article
  • Open Access
4 Citations
2,446 Views
10 Pages

Bacterial and Cellular Response to Yellow-Shaded Surface Modifications for Dental Implant Abutments

  • Tullio Genova,
  • Giorgia Chinigò,
  • Luca Munaron,
  • Paola Rivolo,
  • Anna Luganini,
  • Giorgio Gribaudo,
  • Davide Cavagnetto,
  • Pietro Mandracci and
  • Federico Mussano

20 November 2022

Dental implants have dramatically changed the rehabilitation procedures in dental prostheses but are hindered by the possible onset of peri-implantitis. This paper aims to assess whether an anodization process applied to clinically used surfaces coul...

  • Article
  • Open Access
2,213 Views
16 Pages

Gastric perforation refers to the complete rupture of the gastric wall, leading to the extravasation of gastric contents into the thoracic cavity or peritoneum. Without timely intervention, the expulsion of gastric contents may culminate in profound...

  • Article
  • Open Access
13 Citations
3,406 Views
13 Pages

Titanium Functionalized with Polylysine Homopolymers: In Vitro Enhancement of Cells Growth

  • Maria Contaldo,
  • Alfredo De Rosa,
  • Ludovica Nucci,
  • Andrea Ballini,
  • Davide Malacrinò,
  • Marcella La Noce,
  • Francesco Inchingolo,
  • Edit Xhajanka,
  • Kenan Ferati and
  • Arberesha Bexheti-Ferati
  • + 2 authors

3 July 2021

In oral implantology, the success and persistence of dental implants over time are guaranteed by the bone formation around the implant fixture and by the integrity of the peri-implant mucosa seal, which adheres to the abutment and becomes a barrier t...

  • Review
  • Open Access
42 Citations
9,590 Views
19 Pages

This article focuses on preclinical studies and reviews the available evidence from the literature on dental implant and abutment materials in the last decade. Specifically, different peri-implantitis materials and how surface modifications may affec...

  • Review
  • Open Access
4 Citations
6,107 Views
20 Pages

Bioengineering the Junctional Epithelium in 3D Oral Mucosa Models

  • Marianna Gavriiloglou,
  • Mira Hammad,
  • Jordan M. Iliopoulos,
  • Pierre Layrolle and
  • Danae A. Apatzidou

6 November 2024

Two-dimensional (2D) culture models and animal experiments have been widely used to study the pathogenesis of periodontal and peri-implant diseases and to test new treatment approaches. However, neither of them can reproduce the complexity of human p...

  • Review
  • Open Access
39 Citations
7,726 Views
17 Pages

Potential for Tight Junction Protein–Directed Drug Development Using Claudin Binders and Angubindin-1

  • Yosuke Hashimoto,
  • Keisuke Tachibana,
  • Susanne M. Krug,
  • Jun Kunisawa,
  • Michael Fromm and
  • Masuo Kondoh

17 August 2019

The tight junction (TJ) is an intercellular sealing component found in epithelial and endothelial tissues that regulates the passage of solutes across the paracellular space. Research examining the biology of TJs has revealed that they are complex bi...

  • Article
  • Open Access
27 Citations
3,904 Views
17 Pages

Ultraviolet Treatment of Titanium to Enhance Adhesion and Retention of Oral Mucosa Connective Tissue and Fibroblasts

  • Takayuki Ikeda,
  • Takeshi Ueno,
  • Juri Saruta,
  • Makoto Hirota,
  • Wonhee Park and
  • Takahiro Ogawa

17 November 2021

Peri-implantitis is an unsolved but critical problem with dental implants. It is postulated that creating a seal of gingival soft tissue around the implant neck is key to preventing peri-implantitis. The objective of this study was to determine the e...

  • Article
  • Open Access
710 Views
14 Pages

Impact of Particulate Matter on the Exacerbation of Immunoglobulin A Nephropathy: An Animal Experimental Study

  • Minhyeok Lee,
  • Yeon Woo Lee,
  • Daeun Kang,
  • Ji Woong Son,
  • Wan Jin Hwang,
  • Sin Yung Woo,
  • Mi Jin Hong,
  • Yusin Pak,
  • Se-Hee Yoon and
  • Won Min Hwang
  • + 2 authors

25 September 2025

Particulate matter (PM) exposure is linked to chronic kidney disease; however, its effect on immunoglobulin A (IgA) nephropathy (IgAN) remains unclear. We investigated whether PM exposure exacerbates IgAN in a mouse model. HIGA mice (IgAN model) and...

  • Article
  • Open Access
62 Citations
4,967 Views
16 Pages

Lactobacillus rhamnosus GG Protects the Epithelial Barrier of Wistar Rats from the Pepsin-Trypsin-Digested Gliadin (PTG)-Induced Enteropathy

  • Antonella Orlando,
  • Michele Linsalata,
  • Giusy Bianco,
  • Maria Notarnicola,
  • Benedetta D’Attoma,
  • Maria Principia Scavo,
  • Angela Tafaro and
  • Francesco Russo

7 November 2018

Celiac disease (CD) is a chronic immune-mediated disorder, characterized by enhanced paracellular permeability across the intestinal epithelium. The complex system of intercellular junctions, including tight junctions (TJs) and adherens junctions (AJ...

  • Review
  • Open Access
17 Citations
4,705 Views
15 Pages

Histologic Evaluation of Soft Tissues around Dental Implant Abutments: A Narrative Review

  • Chiara Cinquini,
  • Vincenzo Marchio,
  • Edouard Di Donna,
  • Fortunato Alfonsi,
  • Giacomo Derchi,
  • Marco Nisi and
  • Antonio Barone

27 May 2022

The basis for dental implant success comes not only with the titanium implant osseointegration but also depends on other factors such as the development of a soft tissue barrier, which protects the peri-implant bone from the oral environment. The cha...

  • Article
  • Open Access
14 Citations
5,366 Views
14 Pages

16 August 2021

The use of new devices for the rehabilitation of the severely atrophic maxillae needs validation. We aimed to report the short-term outcome of severely atrophic jaws rehabilitated with zygomatic implants with no implant head angulation placed extrama...

  • Review
  • Open Access
26 Citations
6,329 Views
58 Pages

Direct Action of Non-Digestible Oligosaccharides against a Leaky Gut

  • Maria Eleni Mavrogeni,
  • Mostafa Asadpoor,
  • Paul A. J. Henricks,
  • Ali Keshavarzian,
  • Gert Folkerts and
  • Saskia Braber

7 November 2022

The epithelial monolayer is the primary determinant of mucosal barrier function, and tight junction (TJ) complexes seal the paracellular space between the adjacent epithelial cells and represent the main “gate-keepers” of the paracellular...

  • Article
  • Open Access
3 Citations
1,770 Views
15 Pages

Early Biological Response to Poly(ε-Caprolactone)/Alumina-Toughened Zirconia Composites Obtained by 3D Printing for Peri-Implant Application

  • Riccardo Pedraza,
  • Alessandro Mosca Balma,
  • Ilaria Roato,
  • Clarissa Orrico,
  • Tullio Genova,
  • Giacomo Baima,
  • Giovanni Nicolao Berta,
  • Andrea Giura,
  • Luigi Ribotta and
  • Donatella Duraccio
  • + 2 authors

5 September 2024

The improvement of the mucosal sealing around the implant represents a challenge, one that prompted research into novel materials. To this purpose, a printable poly(ε-caprolactone) (PCL)-based composite loaded with alumina-toughened zirconia...

  • Article
  • Open Access
1 Citations
4,323 Views
34 Pages

3 April 2025

Background/Objectives: The peri-implant soft tissue seal is crucial for the long-term success of subcrestally placed implants (SPIs). However, conventional biologic width—now referred to as supracrestal tissue attachment (STA)—models, ori...

  • Article
  • Open Access
12 Citations
3,417 Views
14 Pages

Biocompatibility of Subperiosteal Dental Implants: Effects of Differently Treated Titanium Surfaces on the Expression of ECM-Related Genes in Gingival Fibroblasts

  • Marco Roy,
  • Alessandro Corti,
  • Silvia Dominici,
  • Alfonso Pompella,
  • Mauro Cerea,
  • Elisa Chelucci,
  • Barbara Dorocka-Bobkowska and
  • Simona Daniele

Introduction: Titanium alloys currently are the most used material for the manufacture of dental endosseous implants. However, in partially or totally edentulous patients, varying degrees of maxillary bone resorption usually occur, making the applica...