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12 Results Found

  • Article
  • Open Access
22 Citations
6,599 Views
10 Pages

MPTP-Treated Zebrafish Recapitulate ‘Late-Stage’ Parkinson’s-like Cognitive Decline

  • Alim A. O. Bashirzade,
  • Sergey V. Cheresiz,
  • Alisa S. Belova,
  • Alexey V. Drobkov,
  • Anastasiia D. Korotaeva,
  • Soheil Azizi-Arani,
  • Amirhossein Azimirad,
  • Eric Odle,
  • Emma-Yanina V. Gild and
  • Allan V. Kalueff
  • + 9 authors

4 February 2022

The zebrafish is a promising model species in biomedical research, including neurotoxicology and neuroactive drug screening. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) evokes degeneration of dopaminergic neurons and is commonly used to model...

  • Article
  • Open Access
9 Citations
4,696 Views
13 Pages

29 August 2019

To better understand the biopsychosocial mechanisms associated with development and maintenance of cannabis use disorder (CUD), we examined frontal alpha asymmetry (FAA) as a measure of approach bias and inhibitory control in cannabis users versus he...

  • Article
  • Open Access
7 Citations
2,895 Views
10 Pages

Background: The objective of this study was to revisit the question concerning whether athletes are better than non-athletes at fundamental cognitive abilities, such as inhibitory control, in addition to also focusing on motivational dispositions and...

  • Communication
  • Open Access
1,183 Views
9 Pages

Shorter Infantile Amnesia in Females: Important Implications for the Next Generation

  • Yuheng Yang,
  • Yuya Sakimoto,
  • Makoto Goshima and
  • Dai Mitsushima

28 February 2025

The sex-specific development of hippocampal learning in juveniles remains unclear. Using an inhibitory avoidance task, we assessed contextual learning in both sexes of juvenile rats. While sex hormone levels and activating effects are low in juvenile...

  • Article
  • Open Access
3 Citations
2,624 Views
11 Pages

Suppressing a Blocked Balance Recovery Step: A Novel Method to Assess an Inhibitory Postural Response

  • David A. E. Bolton,
  • Charlie C. Baggett,
  • Chase A. Mitton,
  • Sara A. Harper and
  • James K. Richardson

21 October 2023

Stepping to recover balance is an important way we avoid falling. However, when faced with obstacles in the step path, we must adapt such reactions. Physical obstructions are typically detected through vision, which then cues step modification. The p...

  • Article
  • Open Access
14 Citations
3,566 Views
23 Pages

Aqueous Dried Extract of Skytanthus acutus Meyen as Corrosion Inhibitor of Carbon Steel in Neutral Chloride Solutions

  • Luis Cáceres,
  • Yohana Frez,
  • Felipe Galleguillos,
  • Alvaro Soliz,
  • Benito Gómez-Silva and
  • Jorge Borquez

9 December 2021

The implementation of corrosion engineering control methods and techniques is crucial to extend the life of urban and industrial infrastructure assets and industrial equipment affected by natural corrosion. Then, the search of stable and environmenta...

  • Review
  • Open Access
2 Citations
1,494 Views
15 Pages

The transgenic animals have been yielding invaluable insights into amyloid pathology by replicating the key features of Alzheimer’s disease (AD). However, there is no clear relationship between senile plaques and memory deficits. Instead, cogni...

  • Article
  • Open Access
29 Citations
5,292 Views
15 Pages

Ginsenosides Rg5 and Rk1 Enriched Cultured Wild Ginseng Root Extract Bioconversion of Pediococcus pentosaceus HLJG0702: Effect on Scopolamine-Induced Memory Dysfunction in Mice

  • Kyu Sup An,
  • Yeo Ok Choi,
  • So Min Lee,
  • Hyeon Yeol Ryu,
  • Su Jin Kang,
  • Yong Yeon,
  • Yu Ri Kim,
  • Jae Geun Lee,
  • Chul Joong Kim and
  • Kyung Seuk Song
  • + 3 authors

20 May 2019

Wild ginseng is known to contain additional physiologically and pharmacologically active substances than common ginseng. The utilization of this herb can be maximized by altering its composition via tissue culture generating adventitious roots. We en...

  • Article
  • Open Access
2,250 Views
22 Pages

Transgenerational Epigenetic Inheritance of Early-Life Stress from Grand-Dams Through Paternal Gametes: Impaired Social Cognition and Reduced Reactivity to Aversive Predictors in DAT-HET Rats

  • Eleonora D’Antonio,
  • Gioia Zanfino,
  • Concetto Puzzo,
  • Micaela Capobianco,
  • Francesco Mannella,
  • Vincenzo De Laurenzi,
  • Giuseppe Curcio and
  • Walter Adriani

9 September 2025

Transgenerational epigenetic inheritance has emerged as a compelling mechanism by which early-life stress can shape behavior in descendants with no direct exposure to trauma. However, whether such heritable modifications affect subtle behavioral phen...

  • Article
  • Open Access
4 Citations
3,964 Views
12 Pages

To determine the critical timing for learning and the associated synaptic plasticity, we analyzed developmental changes in learning together with training-induced plasticity. Rats were subjected to an inhibitory avoidance (IA) task prior to weaning....

  • Article
  • Open Access
7 Citations
2,395 Views
10 Pages

In Vitro Modulation of Complement Activation by Therapeutically Prospective Analogues of the Marine Polychaeta Arenicin Peptides

  • Ilia A. Krenev,
  • Pavel V. Panteleev,
  • Ekaterina S. Umnyakova,
  • Nikolay P. Gorbunov,
  • Valeria A. Kostevich,
  • Sergey V. Balandin,
  • Tatiana V. Ovchinnikova,
  • Galina M. Aleshina and
  • Mikhail N. Berlov

28 September 2022

The widespread resistance to antibiotics in pathogenic bacteria makes the development of a new generation of antimicrobials an urgent task. The development of new antibiotics must be accompanied by a comprehensive study of all of their biological act...

  • Article
  • Open Access
5 Citations
3,455 Views
18 Pages

Biphenylalkoxyamine Derivatives–Histamine H3 Receptor Ligands with Butyrylcholinesterase Inhibitory Activity

  • Dorota Łażewska,
  • Paula Zaręba,
  • Justyna Godyń,
  • Agata Doroz-Płonka,
  • Annika Frank,
  • David Reiner-Link,
  • Marek Bajda,
  • Dorota Stary,
  • Szczepan Mogilski and
  • Katarzyna Kieć-Kononowicz
  • + 4 authors

11 June 2021

Neurodegenerative diseases, e.g., Alzheimer’s disease (AD), are a key health problem in the aging population. The lack of effective therapy and diagnostics does not help to improve this situation. It is thought that ligands influencing multiple but i...