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5 Results Found

  • Article
  • Open Access
5 Citations
2,533 Views
11 Pages

7 April 2025

Background: According to the ISSVA 2018 classification, arteriovenous malformations (AVMs) are high-flow vascular malformations, distinct from low-flow lesions. About 60% of extracranial AVMs occur in the head and neck, making their management a focu...

(This article belongs to the Special Issue Vascular Surgery: Current Advances and Future Directions)
  • Article
  • Open Access
8 Citations
2,963 Views
14 Pages

Bleomycin Electrosclerotherapy (BEST) for Slow-Flow Malformations of the Upper Aerodigestive Tract

  • Veronika Vielsmeier,
  • Vanessa F. Schmidt,
  • Florian Obereisenbuchner,
  • Natascha Platz Batista da Silva,
  • Walter A. Wohlgemuth,
  • Daniel Puhr-Westerheide,
  • Max Seidensticker,
  • Jens Ricke,
  • Thomas Kühnel and
  • Caroline T. Seebauer
  • + 2 authors

Background/Objectives: Bleomycin electrosclerotherapy (BEST), which combines intralesional bleomycin administration with electroporation, enhances drug uptake and has shown efficacy in treating vascular malformations resistant to conventional therapi...

(This article belongs to the Special Issue New Perspectives in the Treatment of Head and Neck Vascular Malformations)
  • Article
  • Open Access
6 Citations
2,347 Views
9 Pages

Bleomycin Electrosclerotherapy for Peripheral Low-Flow Venous and Lymphatic Malformations in Children: A Monocentric Case Series

  • Edoardo Guida,
  • Alessandro Boscarelli,
  • Zeljko Zovko,
  • Matea Peric-Anicic,
  • Marianna Iaquinto,
  • Maria-Grazia Scarpa,
  • Sonia Maita,
  • Damiana Olenik,
  • Daniela Codrich and
  • Jürgen Schleef

1 September 2025

Background: Vascular malformations are relatively common in children. Current therapeutic strategies include observation, medical therapy, sclerotherapy or embolization, laser therapy, cryoablation, and surgery, depending on the type and anatomical l...

(This article belongs to the Special Issue Advances in Pediatric Surgery: Innovative Approaches and Emerging Technologies)
  • Review
  • Open Access
2 Citations
1,639 Views
18 Pages

The Rising Power of Electrochemotherapy in Musculoskeletal Oncology

  • Nicolas Papalexis,
  • Giuliano Peta,
  • Simone Quarchioni,
  • Laura Campanacci,
  • Alessandro Gasbarrini,
  • Giuseppe Tedesco,
  • Michela Carta,
  • Maddalena Di Carlo,
  • Marco Miceli and
  • Giancarlo Facchini

28 February 2026

Electrochemotherapy is a minimally invasive treatment based on the principle of reversible electroporation of target cells in pathologic tissues in order to increase the local effect of chemotherapeutic agents. The mechanism of action relies on tempo...

(This article belongs to the Section Bone and Soft Tissue Oncology)
  • Review
  • Open Access
3 Citations
7,237 Views
10 Pages

Lymphatic malformations (LMs) are benign, congenital vascular anomalies caused by abnormal lymphangiogenesis during embryology, often presenting as fluid-filled cystic lesions. Though LMs can affect any part of the body except the brain, they primari...