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26 Results Found

  • Article
  • Open Access
20 Citations
1,531 Views
5 Pages

Cystic lymph node metastasis in papillary thyroid carcinoma

  • Edita Mišeikytė-Kaubrienė,
  • Mantas Trakymas and
  • Albertas Ulys

17 June 2008

Background. Thyroid cancer, especially papillary carcinoma, metastasizes most often into cervical lymph nodes. Cervical ultrasound and ultrasound-guided fine-needle aspiration biopsy are the most sensitive modalities in detecting locoregional neck re...

  • Review
  • Open Access
12 Citations
3,454 Views
13 Pages

Occult Neck Metastases in Head and Neck Adenoid Cystic Carcinoma: A Systematic Review and Meta-Analysis

  • Jacopo Zocchi,
  • Matteo Campa,
  • Giulia Bianchi,
  • Oreste Iocca,
  • Pasquale Di Maio,
  • Gerardo Petruzzi,
  • Silvia Moretto,
  • Flaminia Campo,
  • Armando De Virgilio and
  • Vincent Vander Poorten
  • + 1 author

22 August 2022

Introduction: Adenoid cystic carcinoma (AdCC) is a rare tumor whose clinical course is burdened by local recurrence and distant dissemination. Lymph node metastasis is not believed to be common and its clinical impact is controversial. The aim of thi...

  • Case Report
  • Open Access
1 Views
2 Pages

A 69-year-old female with recurrent esophageal cancer and multiple lymph node metastases and vomiting was admitted to our hospital. A computed tomography (CT) scan showed a lymph node metastasis that had become cystic and enlarged, and was suggested...

  • Interesting Images
  • Open Access
3,221 Views
5 Pages

In patients with thyroid nodules, if the cervical lymph nodes gradually enlarge, a histological confirmation is required to rule out malignancy. Here is a case of benign intranodal thyroid tissue with cystic changes resembling lymph node metastasis o...

  • Article
  • Open Access
16 Citations
3,762 Views
11 Pages

31 July 2022

Consistent standards regarding whether postoperative adjuvant chemotherapy is required in the treatment of adenoid cystic carcinoma of the breast (ACCB) are currently lacking. Using clinical data from the Surveillance, Epidemiology, and End Results (...

  • Review
  • Open Access
23 Citations
8,170 Views
19 Pages

Histopathological Aspects of the Prognostic Factors for Salivary Gland Cancers

  • Haruto Nishida,
  • Takahiro Kusaba,
  • Kazuhiro Kawamura,
  • Yuzo Oyama and
  • Tsutomu Daa

15 February 2023

Salivary gland cancers (SGCs) are diagnosed using histopathological examination, which significantly contributes to their progression, including lymph node/distant metastasis or local recurrence. In the current World Health Organization (WHO) Classif...

  • Case Report
  • Open Access
2 Citations
4,156 Views
8 Pages

Primary Fallopian Tube Carcinoma: An Extremely Rare Gynecological Cancer Misdiagnosed Intraoperatively as Benign Ovarian Neoplasm: A Case Report

  • Efthymia Thanasa,
  • Dimitra Stamouli,
  • Ektoras-Evangelos Gerokostas,
  • Konstantina Balafa,
  • Nikoleta Koutalia and
  • Ioannis Thanasas

22 April 2022

Primary fallopian tube carcinoma is very rare. Diagnosis is challenging. The description of our case concerns an asymptomatic 71-year-old patient who came for a routine gynecological examination. Imaging of the pelvis revealed the presence of a two-c...

  • Review
  • Open Access
18 Citations
4,072 Views
12 Pages

2 July 2021

Squamous cell carcinoma of unknown primary (SCCUP) is a challenging diagnostic subgroup of oropharyngeal squamous cell carcinoma (OPSCC). The incidence of SCCUP is increasing in parallel with the well-documented increase in OPSCC and is likewise driv...

  • Case Report
  • Open Access
1 Citations
2,537 Views
9 Pages

Gastric Metastasis Mimicking Early Gastric Cancer from Invasive Ductal Carcinoma of the Breast: Case Report and Literature Review

  • Kwon Cheol Yoo,
  • Dae Hoon Kim,
  • Sungmin Park,
  • HyoYung Yun,
  • Dong Hee Ryu,
  • Jisun Lee and
  • Seung-Myoung Son

13 June 2024

Backgound and Objectives: Gastric metastasis from invasive ductal breast cancer (BC) is rare. It mainly occurs in patients with lobular BC. The occurrence of multiple metastases is typically observed several years after the primary diagnosis. Endosco...

  • Case Report
  • Open Access
10 Citations
1,222 Views
4 Pages

CT Imaging Features of Thin-Walled Cavitary Squamous Cell Lung Cancer

  • Lucyna Opoka,
  • Monika Szturmowicz,
  • Karina Oniszh,
  • Damian Korzybski,
  • Zbigniew Podgajny,
  • Katarzyna Błasińska-Przerwa,
  • Małgorzata Szołkowska and
  • Iwona Bestry

30 April 2019

Primary lung cancer manifesting as a thin-walled solitary cavity, occurs relatively infrequently. The most common histologic type presenting such a pattern is squamous cell cancer, followed by adenocarcinoma, and finally—large cell cancer. Cavitation...

  • Systematic Review
  • Open Access
4 Citations
2,293 Views
23 Pages

Primary Carcinomas of the Episiotomy Scar Site: A Systematic Literature Review

  • Andrea Palicelli,
  • Federica Torricelli,
  • Gabriele Tonni,
  • Alessandra Bisagni,
  • Eleonora Zanetti,
  • Magda Zanelli,
  • Venus Damaris Medina-Illueca,
  • Beatrice Melli,
  • Maurizio Zizzo and
  • Andrea Morini
  • + 10 authors

Episiotomy is a perineal incision enlarging the vaginal opening during labor, preventing severe perineal/vaginal/ano-rectal lacerations. We performed a systematic literature review (PRISMA guidelines; Pubmed, Scopus and Web of Science databases) of p...

  • Article
  • Open Access
4 Citations
3,608 Views
15 Pages

Pancreatic Cystic Tumors: A Single-Center Observational Study

  • Beata Jabłońska,
  • Arkadiusz Gudz,
  • Tomasz Hinborch,
  • Bartosz Bujała,
  • Katarzyna Biskup and
  • Sławomir Mrowiec

27 January 2023

Background and Objectives: The aim of the study was to analyze the prevalence and characteristics of pancreatic cystic tumors (PCTs). Material and Methods: A retrospective analysis of the medical records of 124 patients, 102 (69%) women and 46 (31%)...

  • Article
  • Open Access
4 Citations
1,656 Views
11 Pages

Dose-Escalated Radiotherapy for Primary Tracheobronchial Adenoid Cystic Carcinoma

  • Jeong Ha Lee,
  • Jeong Yun Jang,
  • Jae Myoung Noh,
  • Kyungmi Yang and
  • Hongryull Pyo

3 June 2024

Primary tracheobronchial adenoid cystic carcinoma (ACC) is a rare malignancy, so the optimal radiotherapy (RT) dose remains unestablished. We aimed to evaluate the effectiveness of dose-escalated RT for primary tracheobronchial ACC. We retrospectivel...

  • Article
  • Open Access
20 Citations
3,875 Views
13 Pages

Validation of Ultrasound Risk Stratification Systems for Cervical Lymph Node Metastasis in Patients with Thyroid Cancer

  • Ji Ye Lee,
  • Roh-Eul Yoo,
  • Jung Hyo Rhim,
  • Kyung Hoon Lee,
  • Kyu Sung Choi,
  • Inpyeong Hwang,
  • Koung Mi Kang and
  • Ji-hoon Kim

23 April 2022

A malignancy risk stratification system (RSS) for cervical lymph nodes (LNs) has not been fully established. This study aimed to validate the current RSS for the diagnosis of cervical LN metastasis in thyroid cancer. In total, 346 LNs from 282 consec...

  • Article
  • Open Access
1,537 Views
13 Pages

13 February 2025

Background/Objectives: Guidelines for the risk stratification of thyroid nodules are based on certain well-recognized sonographic features of nodules. However, significant variations in reported sensitivity and specificity values are observed due to...

  • Interesting Images
  • Open Access

Rare Case of Squamous Cell Carcinoma Arising from an Intraosseous Epidermal Cyst: A Diagnostic Challenge

  • Jiro Ichikawa,
  • Kojiro Onohara,
  • Tomohiro Inoue,
  • Masanori Wako,
  • Tetsuhiro Hagino,
  • Kouhei Mitsui,
  • Tomonori Kawasaki and
  • Hirotaka Haro

12 December 2025

We report a rare case of squamous cell carcinoma (SCC) arising from an intraosseous epidermal cyst (EC) in the distal phalanx of the left thumb. A 76-year-old male presented with progressive thumb pain experienced over the previous six months. Radiog...

  • Review
  • Open Access
7 Citations
15,667 Views
18 Pages

Basal Cell Carcinoma: Diagnosis, Management and Prevention

  • Peerzada Umar Farooq Baba,
  • Ashfaq ul Hassan,
  • Junaid Khurshid and
  • Adil Hafeez Wani

10 April 2024

Basal cell carcinoma (BCC) is a slow-growing, locally aggressive, rarely metastasizing, low-grade cutaneous neoplasm that arises from the epidermal basal layer and invades the adjoining tissues. It is the most common skin cancer. It is fairly common...

  • Article
  • Open Access
11 Citations
2,895 Views
14 Pages

Multiparametric MRI Evaluation of Oropharyngeal Squamous Cell Carcinoma. A Mono-Institutional Study

  • Francesca Piludu,
  • Simona Marzi,
  • Emma Gangemi,
  • Alessia Farneti,
  • Laura Marucci,
  • Aldo Venuti,
  • Maria Benevolo,
  • Barbara Pichi,
  • Raul Pellini and
  • Francesca Sperati
  • + 3 authors

28 August 2021

The aim of this paper is to define the pre-treatment radiological characteristics of oropharyngeal squamous cell carcinoma (OPSCC) using morphological and non-morphological magnetic resonance imaging (MRI), based on HPV status, in a single-institutio...

  • Article
  • Open Access
2,683 Views
14 Pages

Mucoepidermoid Carcinoma of the Minor Salivary Glands Diagnosed by High-Definition Ultrasound and Fine-Needle Aspiration: A Milan System-Based Retrospective Study

  • Luisa Limongelli,
  • Marta Forte,
  • Gianfranco Favia,
  • Fabio Dell’Olio,
  • Giuseppe Ingravallo,
  • Eliano Cascardi,
  • Eugenio Maiorano,
  • Alfonso Manfuso,
  • Chiara Copelli and
  • Antonio d’Amati
  • + 1 author

Background/Objectives: Mucoepidermoid carcinoma (MEC) is the most common malignant tumor of the minor salivary glands, often affecting the hard palate. Preoperative diagnosis and surgical planning are challenging due to anatomical complexity and limi...

  • Systematic Review
  • Open Access
1 Citations
2,526 Views
20 Pages

MRI for Differentiation between HPV-Positive and HPV-Negative Oropharyngeal Squamous Cell Carcinoma: A Systematic Review

  • Linda L. Chen,
  • Iris Lauwers,
  • Gerda Verduijn,
  • Marielle Philippens,
  • Renske Gahrmann,
  • Marta E. Capala and
  • Steven Petit

31 May 2024

Human papillomavirus (HPV) is an important risk factor for oropharyngeal squamous cell carcinoma (OPSCC). HPV-positive (HPV+) cases are associated with a different pathophysiology, microstructure, and prognosis compared to HPV-negative (HPV−) c...

  • Article
  • Open Access
6 Citations
10,494 Views
20 Pages

Intraoperative Appearance of Endosalpingiosis: A Single-Center Experience of Laparoscopic Findings and Systematic Review of Literature

  • Laurin Burla,
  • Dimitrios Rafail Kalaitzopoulos,
  • Anna Mrozek,
  • Markus Eberhard and
  • Nicolas Samartzis

27 November 2022

Background: Endosalpingiosis is assumed to be the second most common benign peritoneal pathology after endometriosis in women. Although recent studies indicate a significant association with gynecologic malignancies, many underlying principles remain...

  • Interesting Images
  • Open Access
8 Citations
6,562 Views
5 Pages

Ovarian gynandroblastoma (GAB) is an extremely rare sex cord-stromal tumor showing morphological evidence of both female (granulosa cell tumor) and male (Sertoli–Leydig cell tumor (SLCT)) components. Almost all GAB cases have been reported in c...

  • Article
  • Open Access
4 Citations
2,424 Views
12 Pages

Oncological Outcomes and Patterns of Recurrence after the Surgical Resection of an Invasive Intraductal Papillary Mucinous Neoplasm versus Primary Pancreatic Ductal Adenocarcinoma: An Analysis from the German Cancer Registry Group of the Society of German Tumor Centers

  • Thaer S. A. Abdalla,
  • Jannis Duhn,
  • Monika Klinkhammer-Schalke,
  • Sylke Ruth Zeissig,
  • Kees Kleihues-van Tol,
  • Kim C. Honselmann,
  • Rüdiger Braun,
  • Markus Kist,
  • Louisa Bolm and
  • Lennart von Fritsch
  • + 7 authors

26 May 2024

Background: Intraductal papillary mucinous neoplasms (IPMNs) are premalignant cystic neoplasms of the pancreas (CNPs), which can progress to invasive IPMN and pancreatic cancer. The available literature has shown controversial results regarding progn...

  • Review
  • Open Access
1 Citations
7,848 Views
16 Pages

Transperineal Vulvar Ultrasound: A Review of Normal and Abnormal Findings with a Proposed Standardized Methodology

  • Nina Montik,
  • Camilla Grelloni,
  • Giovanni Delli Carpini,
  • Jessica Petrucci,
  • Jacopo Di Giuseppe and
  • Andrea Ciavattini

The vulva is a complex anatomical organ that may present with a wide range of pathologies. Even if it can be easily investigated, correctly interpreting vulvar appearance is often challenging. Vulvar ultrasound is an emerging diagnostic technique tha...

  • Article
  • Open Access
943 Views
17 Pages

Pleuropulmonary Blastoma in Children: A Nationwide Multicenter Study

  • Barbara Tejza,
  • Marta Hetman,
  • Jadwiga Węcławek-Tompol,
  • Krzysztof Kałwak,
  • Olga Rutynowska,
  • Bożenna Dembowska-Bagińska,
  • Agata Sobocińska-Mirska,
  • Paweł Łaguna,
  • Ewa Bień and
  • Ninela Irga-Jaworska
  • + 10 authors

2 October 2025

Background/Objectives: This study involved an analysis of clinical data, histological types, genetic predisposition, treatment and outcomes in PPB in children. Patients and methods: We conducted a retrospective review of children treated for PPB at P...

  • Systematic Review
  • Open Access
17 Citations
4,904 Views
17 Pages

3 January 2024

Background: Intraoral adenoid cystic carcinoma (ACC) arising from minor salivary glands (MSG) is a rare malignancy associated with delayed diagnosis and unfavorable outcomes. This study aimed to comprehensively review ACC of MSGs, focusing on clinica...