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14 Results Found

  • Article
  • Open Access
17 Citations
3,534 Views
13 Pages

Genomic Selection for Milk Production Traits in Xinjiang Brown Cattle

  • Menghua Zhang,
  • Hanpeng Luo,
  • Lei Xu,
  • Yuangang Shi,
  • Jinghang Zhou,
  • Dan Wang,
  • Xiaoxue Zhang,
  • Xixia Huang and
  • Yachun Wang

7 January 2022

One-step genomic selection is a method for improving the reliability of the breeding value estimation. This study aimed to compare the reliability of pedigree-based best linear unbiased prediction (PBLUP) and single-step genomic best linear unbiased...

  • Article
  • Open Access
3 Citations
1,227 Views
18 Pages

Analysis of Population Structure and Selective Signatures for Milk Production Traits in Xinjiang Brown Cattle and Chinese Simmental Cattle

  • Kailun Ma,
  • Xue Li,
  • Shengchao Ma,
  • Menghua Zhang,
  • Dan Wang,
  • Lei Xu,
  • Hong Chen,
  • Xuguang Wang,
  • Aladaer Qi and
  • Qiuming Chen
  • + 2 authors

25 February 2025

This study aims to elucidate the population structure and genetic diversity of Xinjiang brown cattle (XJBC) and Chinese Simmental cattle (CSC) while conducting genome-wide selective signatures analyses to identify selected genes associated with milk...

  • Article
  • Open Access
337 Views
17 Pages

Analysis of Inbreeding Coefficient and Genetic Diversity in Xinjiang Brown Cattle Based on Pedigree and ROH Evaluation

  • Kailun Ma,
  • Xue Li,
  • Yanyan Shang,
  • Jiangjiang Wei,
  • Menghua Zhang,
  • Dan Wang,
  • Xixia Huang,
  • Qiuming Chen and
  • Lei Xu

23 December 2025

The Xinjiang Brown cattle (XJBC) is one of China’s five major dual-purpose dairy and beef breeds. Analyzing the genetic diversity of the Xinjiang Brown cattle population lays the theoretical groundwork for identifying and conserving its genetic...

  • Article
  • Open Access
6 Citations
2,153 Views
18 Pages

Transcriptomic Changes and Regulatory Networks Associated with Resistance to Mastitis in Xinjiang Brown Cattle

  • Dan Wang,
  • Haiyan Yang,
  • Shengchao Ma,
  • Tingting Liu,
  • Mengjie Yan,
  • Mingming Dong,
  • Menghua Zhang,
  • Tao Zhang,
  • Xiaoxue Zhang and
  • Hong Chen
  • + 2 authors

7 April 2024

Xinjiang brown cattle are highly resistant to disease and tolerant of roughage feeding. The identification of genes regulating mastitis resistance in Xinjiang brown cattle is a novel means of genetic improvement. In this study, the blood levels of IL...

  • Article
  • Open Access
9 Citations
2,007 Views
25 Pages

Genome-Wide Association Study on Body Conformation Traits in Xinjiang Brown Cattle

  • Menghua Zhang,
  • Yachun Wang,
  • Qiuming Chen,
  • Dan Wang,
  • Xiaoxue Zhang,
  • Xixia Huang and
  • Lei Xu

30 September 2024

Body conformation traits are linked to the health, longevity, reproductivity, and production performance of cattle. These traits are also crucial for herd selection and developing new breeds. This study utilized pedigree information and phenotypic (1...

  • Article
  • Open Access
11 Citations
2,288 Views
11 Pages

Methylation Levels in the Promoter Region of FHIT and PIAS1 Genes Associated with Mastitis Resistance in Xinjiang Brown Cattle

  • Liwei Zhong,
  • Shengchao Ma,
  • Dan Wang,
  • Menghua Zhang,
  • Yuezhen Tian,
  • Junmin He,
  • Xiaoxue Zhang,
  • Lei Xu,
  • Cuiling Wu and
  • Kechuan Tian
  • + 3 authors

29 May 2023

Mastitis causes serious economic losses in the dairy industry, but there are no effective treatments or preventive measures. In this study, the ZRANB3, PIAS1, ACTR3, LPCAT2, MGAT5, and SLC37A2 genes in Xinjiang brown cattle, which are associated with...

  • Article
  • Open Access
1,047 Views
16 Pages

Identification of Genomic Structural Variations in Xinjiang Brown Cattle by Deep Sequencing and Their Association with Body Conformation Traits

  • Dan Wang,
  • Tao Zhang,
  • Menghua Zhang,
  • Qiuming Chen,
  • Mengjie Yan,
  • Shengchao Ma,
  • Jiangkun Wang,
  • Xiaoxue Zhang,
  • Kailun Ma and
  • Xixia Huang
  • + 1 author

Xinjiang Brown cattle is an elite dual-purpose breed (raised for dairy and beef) developed in China. To elucidate its genomic architecture, we conducted whole-genome resequencing of 169 Xinjiang Brown cattle, followed by structural variation (SV) det...

  • Article
  • Open Access
2 Citations
2,147 Views
11 Pages

Comparative Study of Bacterial Microbiota Differences in the Rumen and Feces of Xinjiang Brown and Holstein Cattle

  • Haibo Lu,
  • Shaokan Chen,
  • Fengjie Li,
  • Guoxing Zhang,
  • Juan Geng,
  • Menghua Zhang,
  • Xixia Huang and
  • Yachun Wang

10 June 2024

Xinjiang Brown cattle are a unique and widely distributed breed of dual-purpose cattle in the Xinjiang area of China, whose milk production performance differs from Holstein cattle. It has been known that variations in bacterial species of the gastro...

  • Article
  • Open Access
5 Citations
2,263 Views
15 Pages

DNA methylation is a form of epigenetic regulation, having pivotal parts in controlling cellular expansion and expression levels within genes. Although blood DNA methylation has been studied in humans and other species, its prominence in cattle is la...

  • Article
  • Open Access
3 Citations
2,374 Views
16 Pages

Exploration of Genes Related to Intramuscular Fat Deposition in Xinjiang Brown Cattle

  • Yu Gao,
  • Liang Yang,
  • Kangyu Yao,
  • Yiran Wang,
  • Wei Shao,
  • Min Yang,
  • Xinyu Zhang,
  • Yong Wei and
  • Wanping Ren

25 August 2024

The aim of this study was to investigate the differentially expressed genes associated with intramuscular fat deposition in the longissimus dorsi muscle of Xinjiang Brown Bulls. The longissimus dorsi muscles of 10 Xinjiang Brown Bulls were selected u...

  • Article
  • Open Access
398 Views
21 Pages

The SCD5 Gene Modulates Adipogenic Differentiation via the WNT5B Signaling Pathway in Xinjiang Brown Cattle

  • Yiran Wang,
  • Wanping Ren,
  • Wei Shao,
  • Yuxin Zhou,
  • Yili Liu,
  • Junwei Cao,
  • Fengju Wang,
  • Jingdong Bi and
  • Liang Yang

10 December 2025

This study investigated the role of SCD5 in bovine preadipocyte proliferation and adipogenic differentiation. SCD5 overexpression suppressed proliferation, reducing the percentage of EdU-positive cells and overall cell viability (p < 0.05). It als...

  • Article
  • Open Access
1,259 Views
25 Pages

Skins Comparative Analysis of Collagen Functionality and Peptide Bioactivities from Yak, Cattle, and Donkey Skins

  • Yaoyuan Kuai,
  • Yufeng Duan,
  • Xue Yang,
  • Ruheng Shen,
  • Wen Wang,
  • Li Zhang,
  • Long He,
  • Cheng Chen,
  • Xiaojin Yuan and
  • Hongbo Li
  • + 1 author

4 November 2025

Collagen peptides derived from animal skins are valuable bioactive ingredients with diverse nutritional and functional properties. This study systematically compared the nutritional value, collagen structure function properties, and bioactivities of...

  • Article
  • Open Access
42 Citations
5,910 Views
10 Pages

Changes in Physical Meat Traits, Protein Solubility, and the Microstructure of Different Beef Muscles during Post-Mortem Aging

  • Yong-Hong Feng,
  • Song-Shan Zhang,
  • Bao-Zhong Sun,
  • Peng Xie,
  • Kai-Xin Wen and
  • Chen-Chen Xu

19 June 2020

This study was performed to compare the differences in pH, myofibril fragmentation index (MFI), total protein solubility (TPS), sarcoplasmic protein solubility (SPS), myofibrillar protein solubility (MPS), and the microstructure of seven beef muscles...

  • Article
  • Open Access
3 Citations
1,816 Views
20 Pages

18 November 2024

Blood is an important component for maintaining animal lives and synthesizing sugars, lipids, and proteins in organs. Revealing the relationship between genes and metabolite expression and milk somatic cell count (SCC), milk fat percentage, milk prot...