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20 Results Found

  • Article
  • Open Access
3 Citations
4,026 Views
10 Pages

Association of Prenatal Maternal Anemia with Tics and Tourette’s Syndrome in Offspring

  • Yi-Chun Liu,
  • Vincent Chin-Hung Chen,
  • Yin-To Liao and
  • Yi-Lung Chen

17 October 2021

Iron deficiency anemia (IDA) accounts for most of the anemia in pregnancy, and iron is essential for neurodevelopment. Tics and Tourette’s syndrome (TS) are neurodevelopmental disorders that manifest in childhood. A few studies reported an inconclusi...

  • Article
  • Open Access
2 Citations
8,964 Views
15 Pages

The Impact of Montelukast Duration on the Risk of Neuropsychiatric Disorders in Children with Asthma: A Population-Based Cohort Study

  • Wei-Te Lei,
  • Chien-Yu Lin,
  • Szu-Hung Chu,
  • Li-Ching Fang,
  • Yu-Hsuan Kao,
  • Po-Li Tsai,
  • Yu-Wen Lin,
  • Fung-Chang Sung and
  • Shu-I Wu

Background/Objectives: Asthma is one of the most common chronic diseases in children, and montelukast is widely prescribed to manage symptoms. However, concerns have emerged regarding its potential association with neuropsychiatric disorders. This st...

  • Review
  • Open Access
561 Views
24 Pages

Tourette syndrome (TS), or Tourette’s, is a tic disorder (TD) belonging to a group of neuropsychiatric conditions marked by recurrent motor movements or vocalizations known as tics. TD, including TS, typically begins in childhood between 4 and...

  • Article
  • Open Access
1 Citations
2,599 Views
26 Pages

24 April 2024

Background/Objectives: Tourette Syndrome (TS), Obsessive Compulsive Disorder (OCD), and Body-Focused Repetitive Behaviors (BFRB) are three disorders that share many similarities in terms of phenomenology, neuroanatomy, and functionality. However, des...

  • Editorial
  • Open Access
2 Citations
6,216 Views
7 Pages

Despite recent giant leaps in understanding Gilles de la Tourette’s syndrome (now Tourette Disorder in the DSM 5), accurate multi-modal description, rigorous assessment procedures, and the improvement of evidence-based treatment currently pose a cons...

  • Article
  • Open Access
2 Citations
7,017 Views
15 Pages

Unpacking Tourette Syndrome in Children: Insights into Prevalence and Comorbidities from NSCH Data

  • Sasidhar Gunturu,
  • Mahdieh Saeidi,
  • Omar Alzein,
  • Kamyar Jafari,
  • Mona Salehi and
  • Sanobar Jaka

23 February 2025

Background: Tourette syndrome is a neurodevelopmental disorder characterized by multiple motor and vocal tics. Although Tourette syndrome is known to have various comorbidities, comprehensive data on its prevalence and associated conditions in a larg...

  • Review
  • Open Access
16 Citations
6,843 Views
12 Pages

8 October 2022

Much of the research regarding Tourette’s syndrome (TS) has focused on why certain individuals develop tics while others do not. However, a separate line of research focuses on the momentary influences that cause tics to increase or decrease in...

  • Article
  • Open Access
12 Citations
4,614 Views
9 Pages

17 January 2022

Tourette Syndrome (TS) is a neurodevelopmental condition characterized by the presence of tics and associated behavioral problems. Yale Global Tic Severity Scale (YGTSS), The PedsQL Pediatric Pain Questionnaire, and Pediatric Pain Coping Inventory we...

  • Case Report
  • Open Access
2,598 Views
12 Pages

10 January 2025

Background/Objectives: Prosopagnosia is the inability to recognize people by their faces. Developmental prosopagnosia is the hereditary or congenital variant of the condition. The aim of this study was to demonstrate the assessment of developmental p...

  • Article
  • Open Access
2 Citations
2,807 Views
8 Pages

22 February 2023

Objectives: To investigate the effect of tiapride and topiramate on patients with Tourette syndrome (TS). Methods: This retrospective analysis included 126 children diagnosed with TS at Children’s Hospital of Chongqing Medical University from 2...

  • Review
  • Open Access
32 Citations
11,121 Views
33 Pages

Progress in Genetic Studies of Tourette’s Syndrome

  • Yanjie Qi,
  • Yi Zheng,
  • Zhanjiang Li and
  • Lan Xiong

20 October 2017

Tourette’s Syndrome (TS) is a complex disorder characterized by repetitive, sudden, and involuntary movements or vocalizations, called tics. Tics usually appear in childhood, and their severity varies over time. In addition to frequent tics, people w...

  • Article
  • Open Access
3 Citations
3,148 Views
14 Pages

Therapeutic Approach to Primary Tic Disorders and Associated Psychiatric Comorbidities

  • Irene Berzosa-Gonzalez,
  • Saul Martinez-Horta,
  • Jesus Pérez-Pérez,
  • Jaime Kulisevsky and
  • Javier Pagonabarraga

7 December 2024

Background/Objectives: The treatment of tics and psychiatric comorbidities is crucial when they affect the patient’s well-being and relationships. However, the optimal pharmacological treatment (PT) tailored to each patient’s phenotype re...

  • Article
  • Open Access
14 Citations
20,775 Views
15 Pages

Efficacy of a Gluten-Free Diet in the Gilles de la Tourette Syndrome: A Pilot Study

  • Luis Rodrigo,
  • Nuria Álvarez,
  • Enrique Fernández-Bustillo,
  • Javier Salas-Puig,
  • Marcos Huerta and
  • Carlos Hernández-Lahoz

7 May 2018

The Gilles de la Tourette syndrome (GTS) and Non-Coeliac Gluten Sensitivity (NCGS) may be associated. We analyse the efficacy of a gluten-free diet (GFD) in 29 patients with GTS (23 children; six adults) in a prospective pilot study. All of them foll...

  • Article
  • Open Access
23 Citations
5,043 Views
12 Pages

The Prevalence and Comorbidity of Tic Disorders and Obsessive-Compulsive Disorder in Chinese School Students Aged 6–16: A National Survey

  • Junjuan Yan,
  • Hu Deng,
  • Yongming Wang,
  • Xiaolin Wang,
  • Tengteng Fan,
  • Shijie Li,
  • Fang Wen,
  • Liping Yu,
  • Fang Wang and
  • Ying Li
  • + 4 authors

Background: Obsessive-compulsive disorder (OCD) and tic disorders (TDs) are closely related and considered to etiologically overlap. Both disorders are characterized by repetitive behaviors. TD and OCD often co-occur. The high comorbidity between OCD...

  • Review
  • Open Access
4 Citations
2,029 Views
25 Pages

Liposomal and Lipid-Based Drug Delivery Systems: Bridging Gut Microbiota and Pediatric Disorder Treatments

  • Raluca Ioana Teleanu,
  • Elena-Theodora Moldoveanu,
  • Adelina-Gabriela Niculescu,
  • Elena Predescu,
  • Eugenia Roza,
  • Iulia Florentina Tincu,
  • Alexandru Mihai Grumezescu and
  • Daniel Mihai Teleanu

The intestine is an important segment of the gastrointestinal tract, which is involved in complex processes that maintain the body’s normal homeostasis. It hosts a vast, diverse, and dynamic microbial community called the gut microbiota, which...

  • Article
  • Open Access
1 Citations
1,049 Views
17 Pages

Pimozide Inhibits Type II but Not Type I Hair Cells in Chicken Embryo and Adult Mouse Vestibular Organs

  • Roberta Giunta,
  • Giulia Cheli,
  • Giorgio Rispoli,
  • Giancarlo Russo and
  • Sergio Masetto

18 December 2024

Background: Pimozide is a conventional antipsychotic drug of the diphenylbutylpiperidine class, widely used for treating schizophrenia and delusional disorders and for managing motor and phonic tics in Tourette’s syndrome. Pimozide is known to...

  • Article
  • Open Access
6 Citations
3,271 Views
14 Pages

Micro-RNAs from Plasma-Derived Small Extracellular Vesicles as Potential Biomarkers for Tic Disorders Diagnosis

  • Yilong Wang,
  • Xuebin Xu,
  • Haihua Chen,
  • Mengying Zhu,
  • Xiaotong Guo and
  • Feng Gao

Tic disorders (TDs) are a series of childhood neuropsychiatric disorders characterized by involuntary motor and/or vocal tics and commonly comorbid with several other psychopathological and/or behavioral disorders (e.g., attention deficit hyperactivi...

  • Article
  • Open Access
10 Citations
5,254 Views
10 Pages

A Pilot Study on Plasma and Urine Neurotransmitter Levels in Children with Tic Disorders

  • Qiao-Qiao Qian,
  • Qian-Qian Tan,
  • Dan Sun,
  • Qing Lu,
  • Ying-Ying Xin,
  • Qian Wu,
  • Yong Zhou,
  • Yang-Xi Liu,
  • Pei-Chao Tian and
  • Zhi-Sheng Liu

Background: Tic disorders (TDs), including Tourette syndrome, are childhood-onset neuropsychiatric disorders characterized by motor and/or vocal tics that commonly affect children’s physical and mental health. The pathogenesis of TDs may be rel...

  • Article
  • Open Access
12 Citations
4,969 Views
13 Pages

Disentangling Restrictive and Repetitive Behaviors and Social Impairments in Children and Adolescents with Gilles de la Tourette Syndrome and Autism Spectrum Disorder

  • Mariangela Gulisano,
  • Rita Barone,
  • Salvatore Alaimo,
  • Alfredo Ferro,
  • Alfredo Pulvirenti,
  • Lara Cirnigliaro,
  • Selena Di Silvestre,
  • Serena Martellino,
  • Nicoletta Maugeri and
  • Renata Rizzo
  • + 2 authors

Gilles de la Tourette syndrome (GTS) and autism spectrum disorder (ASD) are two neurodevelopmental disorders with male predominance, frequently comorbid, that share clinical and behavioral features. The incidence of ASD in patients affected by GTS wa...

  • Article
  • Open Access
27 Citations
7,757 Views
15 Pages

Adaptive Deep Brain Stimulation (aDBS) for Tourette Syndrome

  • Sara Marceglia,
  • Manuela Rosa,
  • Domenico Servello,
  • Mauro Porta,
  • Sergio Barbieri,
  • Elena Moro and
  • Alberto Priori

23 December 2017

Deep brain stimulation (DBS) has emerged as a novel therapy for the treatment of several movement and neuropsychiatric disorders, and may also be suitable for the treatment of Tourette syndrome (TS). The main DBS targets used to date in patients with...