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9 Results Found

  • Article
  • Open Access

Using Machine Learning to Identify Factors Affecting Antibody Production and Adverse Reactions After COVID-19 Vaccination

  • Nahomi Miyamoto,
  • Tohru Yamaguchi,
  • Yoshinori Tamada,
  • Seiya Yamayoshi,
  • Koichi Murashita,
  • Ken Itoh,
  • Seiya Imoto,
  • Norihiro Saito,
  • Tatsuya Mikami and
  • Shigeyuki Nakaji

26 January 2026

Background: Coronavirus disease 2019 (COVID-19) vaccines deliver mRNA packaged in lipid nanoparticles via intramuscular injection. This study investigated several factors influencing antibody production patterns and adverse reactions after vaccinatio...

  • Article
  • Open Access
5 Citations
2,549 Views
11 Pages

Association between Gut Microbiota and Muscle Strength in Japanese General Population of the Iwaki Health Promotion Project

  • Yoshikuni Sugimura,
  • Yichi Yang,
  • Akira Kanda,
  • Akihiro Mawatari,
  • Yoshinori Tamada,
  • Tatsuya Mikami,
  • Shigeyuki Nakaji and
  • Kazushige Ihara

The association between the gut microbiota and muscle strength has garnered attention in the context of mitigating muscle decline. However, many study subjects have been individuals with existing illnesses or the elderly only. This study aims to eluc...

  • Article
  • Open Access
2 Citations
2,681 Views
15 Pages

Does the Protective Effect of Zinc on Telomere Length Depend on the Presence of Hypertension or Type 2 Diabetes? Results from the Iwaki Health Promotion Project, Japan

  • Mahiro Sato,
  • Kyi Mar Wai,
  • Ken Itoh,
  • Yichi Yang,
  • Yuka Uchikawa,
  • Yukihiko Ito,
  • Shigeyuki Nakaji and
  • Kazushige Ihara

16 October 2023

Telomeres, repeated TTAGGG sequences at chromosomal ends, shorten with age and indicate cellular lifespan. Zinc can protect against telomere damage through its anti-oxidative effect. Meanwhile, telomere shortening was correlated with metabolic diseas...

  • Article
  • Open Access
1 Citations
2,626 Views
11 Pages

The correlation between diabetes-related biomarkers and quality of life (QOL) remains unclear. In this cross-sectional study, we investigated the correlation between diabetes-related biomarkers and QOL in a general Japanese population who underwent h...

  • Article
  • Open Access
15 Citations
3,503 Views
11 Pages

Association of Gut Microbial Genera with Heart Rate Variability in the General Japanese Population: The Iwaki Cross-Sectional Research Study

  • Masaya Tsubokawa,
  • Miyuki Nishimura,
  • Tatsuya Mikami,
  • Mizuri Ishida,
  • Takayoshi Hisada and
  • Yoshinori Tamada

7 August 2022

The gut microbiota has become a significant factor associated with health and disease. Although many studies have reported the implications of changes in the gut microbiota on cardiovascular diseases, there are no reports on the relationship between...

  • Article
  • Open Access
5 Citations
2,670 Views
12 Pages

Two Distinct Groups Are Shown to Be at Risk of Diabetes by Means of a Cluster Analysis of Four Variables

  • Ryoma Ito,
  • Satoru Mizushiri,
  • Yuki Nishiya,
  • Shoma Ono,
  • Ayumi Tamura,
  • Kiho Hamaura,
  • Akihide Terada,
  • Jutaro Tanabe,
  • Miyuki Yanagimachi and
  • Makoto Daimon
  • + 4 authors

19 January 2023

Recent attempts to classify adult-onset diabetes using only six diabetes-related variables (GAD antibody, age at diagnosis, BMI, HbA1c, and homeostatic model assessment 2 estimates of b-cell function and insulin resistance (HOMA2-B and HOMA2-IR)) sho...

  • Article
  • Open Access
35 Citations
5,390 Views
13 Pages

Aberrant N-Glycosylation Profile of Serum Immunoglobulins is a Diagnostic Biomarker of Urothelial Carcinomas

  • Toshikazu Tanaka,
  • Tohru Yoneyama,
  • Daisuke Noro,
  • Kengo Imanishi,
  • Yuta Kojima,
  • Shingo Hatakeyama,
  • Yuki Tobisawa,
  • Kazuyuki Mori,
  • Hayato Yamamoto and
  • Chikara Ohyama
  • + 8 authors

6 December 2017

The aim of this study to determine whether the aberrant N-glycosylated serum immunoglobulins (Igs) can be applied as a diagnostic marker of urothelial carcinoma (UC). Between 2009 and 2016, we randomly obtained serum available from 237 UC and also 96...

  • Article
  • Open Access
7 Citations
4,708 Views
11 Pages

Although many studies have reported factors associated with reduced heart rate variability (HRV) in Western populations, evidence is limited among Asian populations. Therefore, we investigated the factors associated with reduced HRV values in a gener...

  • Article
  • Open Access
15 Citations
3,752 Views
12 Pages

Relationship between Selected Trace Elements and Hematological Parameters among Japanese Community Dwellers

  • Kyi Mar Wai,
  • Kaori Sawada,
  • Mika Kumagai,
  • Kazuyoshi Itai,
  • Itoyo Tokuda,
  • Koichi Murashita,
  • Shigeyuki Nakaji and
  • Kazushige Ihara

30 May 2020

This study aimed (1) to assess serum trace elements concentrations and hematological parameters, (2) to evaluate the sex differences in the associations between serum trace elements levels and hematological parameters, and (3) to identify the associa...