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12 Results Found

  • Article
  • Open Access
1,018 Views
41 Pages

1 December 2025

The development of AI systems and benchmarks has been rapidly increasing, yet there has been a disproportionately small amount of examination into the domains used to evaluate these systems. Most benchmarks introduce bias by focusing on a particular...

  • Communication
  • Open Access
1 Citations
2,267 Views
8 Pages

AIQS-DB: Revolutionizing the Simultaneous Analysis of Organic Compounds

  • Quang Minh Bui,
  • Huynh Nhat Minh Nguyen,
  • Van Nhan Le,
  • Thanh Thao Nguyen,
  • Ngoc Minh Truong,
  • Ngoc Tung Nguyen,
  • Quang Huong Le and
  • Quang Trung Nguyen

10 July 2023

This paper reports a database, namely, the Automated Identification and Quantification Database System (AIQS-DB), which consists of three components, including retention times, mass data, and calibration curves, without the requirement to analyze sta...

  • Article
  • Open Access
19 Citations
3,946 Views
16 Pages

5-Aminoisoquinolinone, a PARP-1 Inhibitor, Ameliorates Immune Abnormalities through Upregulation of Anti-Inflammatory and Downregulation of Inflammatory Parameters in T Cells of BTBR Mouse Model of Autism

  • Khaled Alhosaini,
  • Mushtaq A. Ansari,
  • Ahmed Nadeem,
  • Saleh A. Bakheet,
  • Sabry M. Attia,
  • Khalid Alhazzani,
  • Thamer H. Albekairi,
  • Haneen A. Al-Mazroua,
  • Hafiz M. Mahmood and
  • Sheikh F. Ahmad

17 February 2021

Autism spectrum disorder (ASD) covers a range of neurodevelopmental disorders involving impairments in communication and repetitive and stereotyped patterns of behavior and reciprocal social interaction. 5-Aminoisoquinolinone (5-AIQ), a PARP-1 inhibi...

  • Article
  • Open Access
7 Citations
6,971 Views
20 Pages

Adaptation of the Aphasia Impact Questionnaire-21 into Greek: A Reliability and Validity Study

  • Marina Charalambous,
  • Phivos Phylactou,
  • Alexia Kountouri,
  • Marios Serafeim,
  • Loukia Psychogios,
  • Jean-Marie Annoni and
  • Maria Kambanaros

The impact of aphasia on the everyday life of Greek-speaking people with aphasia (PWA) is often underestimated by rehabilitation clinicians. This study explores the adaptation and psychometric properties of the Greek (GR) version of The Aphasia Impac...

  • Article
  • Open Access
2,004 Views
14 Pages

Risk Assessment of Displaced Sediment by an Extreme Event Cyclone in a Peri-Urban Zone Using Bioassays and Analytical Chemistry

  • Louis A. Tremblay,
  • Daisuke Nakajima,
  • Satoshi Endo,
  • Mayuko Yagishita,
  • Hannah Ludlow,
  • Ariana Mackay and
  • Olivier Champeau

31 July 2024

Hawke’s Bay in New Zealand was impacted by Cyclone Gabrielle in 2023, experiencing intense weather conditions and rainfall. Rivers and streams surged beyond their banks, displacing large amounts of sediment. The sewage treatment plant and indus...

  • Article
  • Open Access
1 Citations
2,485 Views
10 Pages

13 June 2022

5-Aminoisoquinoline (5-AIQ) is a water-soluble, potent and selective Poly (ADP-ribose) polymerase 1 (PARP-1) inhibitor, widely used as a biochemical and pharmacological tool to study the inhibitory effect of PARPs enzyme. In this study, a simple, sel...

  • Article
  • Open Access
2 Citations
4,103 Views
12 Pages

Assessing Efficiency in Artificial Neural Networks

  • Nicholas J. Schaub and
  • Nathan Hotaling

14 September 2023

The purpose of this work was to develop an assessment technique and subsequent metrics that help in developing an understanding of the balance between network size and task performance in simple model networks. Here, exhaustive tests on simple model...

  • Review
  • Open Access
12 Citations
5,688 Views
60 Pages

Nanomaterials in Photocatalysis: An In-Depth Analysis of Their Role in Enhancing Indoor Air Quality

  • Enrico Greco,
  • Alessia De Spirt,
  • Alessandro Miani,
  • Prisco Piscitelli,
  • Rita Trombin,
  • Pierluigi Barbieri and
  • Elia Marin

6 February 2025

Since people spend most of their time in indoor environments, they are continuously exposed to various contaminants that threaten human health. The air quality in these settings is therefore a crucial factor in maintaining health safety. In order to...

  • Article
  • Open Access
5 Citations
2,837 Views
12 Pages

Comprehensive Analysis of Organic Micropollutants in Fine Particulate Matter in Hanoi Metropolitan Area, Vietnam

  • Huong Le-Quang,
  • Thao Pham Thi Phuong,
  • Minh Bui-Quang,
  • Dat Nguyen-Tien,
  • Thao Nguyen-Thanh,
  • My Nguyen-Ha,
  • Hikari Shimadera,
  • Akira Kondo,
  • Mui Luong-Viet and
  • Trung Nguyen-Quang

12 December 2022

Rapid urbanization has led to increased environmental pollution in Vietnam, especially air pollution issues. In this study, we used gas chromatography-mass spectrometry with an automated identification and quantification system database to detect and...

  • Article
  • Open Access
1 Citations
2,066 Views
17 Pages

Background/Objectives: In addition to oncological applications, poly(ADP-ribose) polymerase (PARP) inhibitors have potential as anti-inflammatory agents. Colon-targeted delivery of PARP inhibitors has been evaluated as a pharmaceutical strategy to en...

  • Article
  • Open Access
5 Citations
2,128 Views
15 Pages

NIR-Sensitive Squaraine Dye—Peptide Conjugate for Trypsin Fluorogenic Detection

  • Priyanka Balyan,
  • Shekhar Gupta,
  • Sai Kiran Mavileti,
  • Shyam S. Pandey and
  • Tamaki Kato

25 September 2024

Trypsin enzyme has gained recognition as a potential biomarker in several tumors, such as colorectal, gastric, and pancreatic cancer, highlighting its importance in disease diagnosis. In response to the demand for rapid, cost-effective, and real-time...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,822 Views
15 Pages

Whole-Body [18F]-Fluoride PET SUV Imaging to Monitor Response to Dasatinib Therapy in Castration-Resistant Prostate Cancer Bone Metastases: Secondary Results from ACRIN 6687

  • Mark Muzi,
  • Finbarr O’Sullivan,
  • Timothy G. Perk,
  • John P. Muzi,
  • David A. Mankoff,
  • Robert Jeraj,
  • Fenghai Duan and
  • Evan Y. Yu

25 April 2021

ACRIN 6687, a multi-center clinical trial evaluating differential response of bone metastases to dasatinib in men with metastatic castration-resistant prostate cancer (mCRPC), used [18F]-fluoride (NaF) PET imaging. We extend previous ACRIN 6687 dynam...