Special Issue "7th Pan-American Dengue Research Network Meeting: Lima 2020"

Special Issue Editors

Dr. Carlos A. Sariol
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Guest Editor
Unit of Comparative Medicine, Caribbean Primate Research Center, Department of Microbiology and Medical Zoology, Department of Internal Medicine, University of Puerto Rico-Medical Sciences Campus, San Juan, Puerto Rico
Interests: basic research on flavivirus interactions at molecular level and pathogenesis; vaccine development and characterization of novel viruses in non human primate model; also interested and actively involved in clinical trials for several diseases including flavivirus vaccines
Special Issues and Collections in MDPI journals
Dr. Mariana Leguia
Website
Guest Editor
Director, Genomics Laboratory, Pontificia Universidad Católica del Perú
Interests: Study of tropical and neglected infectious diseases using state-of-the-art genomic tools, including ribosome profiling. Particular focus on pathogen discovery and characterization, host-pathogen interactions and changes in gene expression, and evaluation of vaccine efficacy using systems biology approaches
Dr. Daniela Weiskopf
Website
Guest Editor
La Jolla Institute for Immunology, Division of Vaccine Discovery
Interests: T cell response against flaviviruses in general and dengue virus; the characterization of cellular mediated immunity in the context of vaccination and acute disease

Special Issue Information

Dear Colleagues,

PanDengue Net is a non-profit initiative that gathers scientists, researchers, and medical professionals working in the field of arbovirology across the Americas (http://www.pandenguenet.org). The PanDengue Net meeting, which is an event scheduled every two years, brings these researchers together in the context of a 4-day scientific gathering. The meeting allows for the presentation and discussion of recent advances in the field. The main focus is on Dengue, Zika, Chikungunya, and other arboviruses of medical relevance that severely impact public health in the Americas and around the world.

As in previous meetings (2008 Recife, Brazil; 2010 Cancun, Mexico; 2012 Cartagena, Colombia; 2014 Belém, Brazil; 2016 Panama City, Panama; and 2018 Galveston, Texas, USA), the Lima meeting will include pre-eminent scientists from a wide range of fields, including vaccine development, vector research and control, molecular epidemiology, diagnostics, antivirals, viral structure and pathogenesis, and viral immunology. The meeting is essential to the fostering of collaborations among groups and to the discussion of future research strategies needed to strengthen the field. Importantly, the meeting also provides a unique platform for students and junior investigators from across Latin America and the Caribbean, who are usually under-represented in science, to come together under one roof with leading figures in the field.

Dr. Carlos A. Sariol
Dr. Mariana Leguia
Dr. Daniela Weiskopf
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Dengue
  • Zika
  • Chikungunya
  • Yellow fever
  • Mayaro
  • vaccine
  • pathogenesis
  • immunology
  • virology
  • community intervention
  • vector control.

Related Special Issue

Published Papers (2 papers)

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Research

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Open AccessArticle
Efficient Method for Molecular Characterization of the 5′ and 3′ Ends of the Dengue Virus Genome
Viruses 2020, 12(5), 496; https://doi.org/10.3390/v12050496 - 29 Apr 2020
Abstract
Dengue is a mosquito-borne disease that is of major importance in public health. Although it has been extensively studied at the molecular level, sequencing of the 5′ and 3′ ends of the untranslated regions (UTR) commonly requires specific approaches for completion and corroboration. [...] Read more.
Dengue is a mosquito-borne disease that is of major importance in public health. Although it has been extensively studied at the molecular level, sequencing of the 5′ and 3′ ends of the untranslated regions (UTR) commonly requires specific approaches for completion and corroboration. The present study aimed to characterize the 5′ and 3′ ends of dengue virus types 1 to 4. The 5′ and 3′ ends of twenty-nine dengue virus isolates from acute infections were amplified through a modified protocol of the rapid amplification cDNA ends approach. For the 5′ end cDNA synthesis, specific anti-sense primers for each serotype were used, followed by polyadenylation of the cDNA using a terminal transferase and subsequent PCR amplification with oligo(dT) and internal specific reverse primer. At the 3′ end of the positive-sense viral RNA, an adenine tail was directly synthetized using an Escherichia coli poly(A) polymerase, allowing subsequent hybridization of the oligo(dT) during cDNA synthesis. The incorporation of the poly(A) tail at the 5′ and 3′ ends of the dengue virus cDNA and RNA, respectively, allowed for successful primer hybridization, PCR amplification and direct sequencing. This approach can be used for completing dengue virus genomes obtained through direct and next-generation sequencing methods. Full article
(This article belongs to the Special Issue 7th Pan-American Dengue Research Network Meeting: Lima 2020)
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Review

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Open AccessReview
Dengue: A Minireview
Viruses 2020, 12(8), 829; https://doi.org/10.3390/v12080829 - 30 Jul 2020
Abstract
Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a mosquito-borne disease of major public health concern associated with significant morbidity, mortality, and economic cost, particularly in developing countries. Dengue incidence has increased 30-fold in the last [...] Read more.
Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a mosquito-borne disease of major public health concern associated with significant morbidity, mortality, and economic cost, particularly in developing countries. Dengue incidence has increased 30-fold in the last 50 years and over 50% of the world’s population, in more than 100 countries, live in areas at risk of DENV infection. We reviews DENV biology, epidemiology, transmission dynamics including circulating serotypes and genotypes, the immune response, the pathogenesis of the disease as well as updated diagnostic methods, treatments, vector control and vaccine developments. Full article
(This article belongs to the Special Issue 7th Pan-American Dengue Research Network Meeting: Lima 2020)

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

1. Title: Immunity to DENV4 results in better control of Zika replication and higher magnitude of neutralization compared to DENV3 in macaques

2. Title: Current understanding of the role of T cells in dengue, zika and chikungunya virus infections

 

 

 

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