The Safety and Immunogenicity of the Bivalent Omicron-Containing mRNA-1273.214 Booster Vaccine

Dear Colleagues,

A bivalent vaccine from Moderna based on omicron BA.1 was approved for use as a booster dose by the Medicines and Healthcare Products Regulatory Agency. Preliminary data indicated that the vaccine generates a strong immune response against the BA.4 and BA.5 subvariants, which are now dominant worldwide. This new proposal behaves in the same manner as a flu-like situation, where everyone must take their flu vaccine at the start of winter each year and the composition of the vaccine is regularly modified in accordance with circulating strains. The new vaccines are highly effective in preventing disease severity but not transmission. We are pleased to invite you to submit to this Topical Collection for all kinds of manuscripts, such as research articles, brief reports, and communications to promote the knowledge and discussion about COVID-19 vaccines, especially bivalent vaccines. The invited papers broadly cover the safety and immunogenicity of COVID-19 vaccines in normal healthy persons, persons with moderate immunocompromised status and persons with severe immunocompromised status.

Dr. Lalit Batra
Dr. Shailendra Kumar Verma
Collection Editors

Manuscript Submission Information

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