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Toxics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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PFAS Toxicology and Metabolism—2nd Edition

edited by

Denise MacMillan

William S. Baldwin

and

Subham Dasgupta

submission deadline 20 May 2026 | 6 articles | Viewed by 17400 | Submission Open

Keywords: PFAS; toxicity; metabolism; toxicokinetics; adverse outcomes; omics; biotransformation; biomonitoring; new approach methodologies (NAMs); non-targeted analysis (NTA)

(This special issue belongs to the Section Emerging Contaminants)

Environmental Monitoring and Health Risk Assessment of Traffic-Related Air Pollution

edited by

Huanbo Wang

, Tingting Huo and

Li Zhou

submission deadline 20 May 2026 | Viewed by 311 | Submission Open

Keywords: air pollution; particulate matter; health risk assessment; vehicle emission; reactive oxygen species (ROS)

(This special issue belongs to the Section Air Pollution and Health)

Pharmacological and Toxicological Insights into Bioactive Natural Products: From Traditional Use to Mechanistic Understanding

edited by

Maria Loreta Libero

and

Simonetta Cristina Di Simone

submission deadline 20 May 2026 | Viewed by 248 | Submission Open

Keywords: natural products; inflammation; toxicity; safety assessment

(This special issue belongs to the Section Drugs Toxicity)

Ecotoxicology of Emerging Contaminants in the Water Environment

edited by Roberta Bettinetti and Ginevra Boldrocchi

submission deadline 21 May 2026 | 2 articles | Viewed by 1979 | Submission Open

Keywords: ecotoxicology; marine pollution; elasmobranchs; zooplankton; trace metals; freshwater; contaminants; plastic pollution; emerging contaminants; legacy contaminants

Aerosol Particles: From Sources to Health Impacts

edited by

Matthias Karl

and

Fujie Zhu

submission deadline 21 May 2026 | 2 articles | Viewed by 1137 | Submission Open

Keywords: atmospheric aerosols; aerosol toxicity; haze pollution; ultrafine particles; aerosol chemistry; source apportionment; dispersion modeling; exposure assessment

(This special issue belongs to the Section Air Pollution and Health)

Hazardous Pollutants in Marine Ecosystems

edited by

Maria Luisa Vannuccini

and

Inmaculada Varó

submission deadline 22 May 2026 | 1 articles | Viewed by 4275 | Submission Open

Keywords: ecotoxicology; nanomaterials; bioaccumulation; biotransformation; biomonitoring; POPs; PAHs

Environmental Drivers of Chronic Disease: From Population Landscapes to Molecular Mechanisms

edited by Jian Hou, Weidong Wu and

Yanjun Guo

submission deadline 22 May 2026 | 2 articles | Viewed by 2097 | Submission Open

Keywords: environmental epidemiology; chronic non-communicable diseases; gene– environment interaction; gut microbiota; oxidative stress; human health

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Classical Environmental Process Modeling, Interpretable Machine Learning, and Their Integrative Innovations—Targeting Atmospheric, Water, and Soil Pollution

edited by

and

submission deadline 22 May 2026 | 1 articles | Viewed by 2014 | Submission Open

Keywords: environmental models; environmental simulation; environmental management; machine learning; deep learning; source apportionment; atmosphere; soil; water

PFAS: Lifespan Health Risks from Early-Life Exposure and Underlying Mechanisms

edited by

Pan Yang

and

Dan Cai

submission deadline 22 May 2026 | Viewed by 422 | Submission Open

Keywords: per- and polyfluoroalkyl substance (PFAS) prenatal exposure; biological barriers; reproductive health; fetal growth and development; metabolic and neurological disorders; lifelong health; molecular mechanisms; risk assessment; developmental origins of health and disease (DOHaD)

Atmospheric Emissions, Exposure, Monitoring and Prediction

edited by

Qingchun Guo

Chong Wei

and Jiamao Zhou

submission deadline 23 May 2026 | 2 articles | Viewed by 1075 | Submission Open

Keywords: high-resolution emission; human exposure; monitoring and data Integration; air quality prediction and forecasting; policy; artificial intelligence; deep learning

(This special issue belongs to the Section Air Pollution and Health)

Potentially Toxic Elements Pollution in Urban and Suburban Environments, 3rd Edition

edited by

Ilaria Guagliardi

submission deadline 25 May 2026 | Viewed by 211 | Submission Open

Keywords: potentially toxic elements (PTEs); environmental geochemistry; soil; sediment; water; air pollution; geogenic and anthropogenic pollutant input; bioavailability; PTE mapping; spatial data analysis

Emerging Pollutants in the Air and Health Risks

edited by

Qi Zhao

and

Gongbo Chen

submission deadline 28 May 2026 | 7 articles | Viewed by 16753 | Submission Open

Keywords: emerging pollutants; air pollution; exposure assessment; risk assessment; novel methodologies; statistical modeling; toxic mechanisms

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Toxicological Effects of Natural Products Derived from Plants or Animals Used in Therapeutical Treatments

edited by

Laura Narciso

and Carla Raggi

submission deadline 29 May 2026 | 1 articles | Viewed by 1145 | Submission Open

Keywords: natural products; plant; animal; therapeutic effect; toxicological evaluation; cytotoxicity; genotoxicity; reproductive toxicity

Genotoxicity of Environmental Pollutants: From Mechanistic Insights to Risk Assessment

edited by

Antonio Cascajosa-Lira

and

Remedios Guzmán-Guillén

submission deadline 29 May 2026 | Viewed by 316 | Submission Open

Keywords: mutagenicity; carcinogenicity; Ames; DNA damage; risk assessment; environmental pollutants; micronucleus

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Analytical Methods and Health Implications of Microplastic Contamination in Food Products

edited by

Kornelia Kadac-Czapska

and

Małgorzata Grembecka

submission deadline 29 May 2026 | Viewed by 238 | Submission Open

Keywords: microplastic contamination; food safety; polymers; plastics; food processing and packaging; pollutant adsorption; human exposure assessment; analytical detection methods; spectroscopic identification

(This special issue belongs to the Section Emerging Contaminants)

Toxicity Assessment of Emerging Organic Pollutants and New Functional Materials

edited by Shuyan Zhao and Xiaojing Yang

submission deadline 30 May 2026 | 1 articles | Viewed by 1785 | Submission Open

Keywords: emerging organic pollutants (EOPs); new functional materials (NFMs); environmental behaviors; risk assessment; environmental monitoring and analysis

(This special issue belongs to the Section Emerging Contaminants)

Exploring Toxicity, Metabolism, and Transformation of Organic Pollutants

edited by

Jianteng Sun

and

Xiaolong Yu

submission deadline 31 May 2026 | 5 articles | Viewed by 11454 | Submission Open

Keywords: emerging organic pollutants; soil pollution; migration and biotransformation; environmental occurrence; metabolism; bioaccumulation; transformation products

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Biomonitoring of Toxic Elements and Emerging Pollutants

edited by

Miguel Motas Guzmán

, Pedro Andreo-Martínez and Juan Jose Ramos

submission deadline 31 May 2026 | 4 articles | Viewed by 8595 | Submission Open

Keywords: environmental health risks; bioaccumulation; biomonitoring; ecotoxicity; emerging contaminants; one health; biological effect monitoring; laboratory tests and validation

(This special issue belongs to the Section Emerging Contaminants)

Emerging Methodologies in Toxicology for Environmental Safety Assessment

edited by

Melissa Faria

Juliette Bedrossiantz

and

Marcelino Miguel Guedes de Jesus Oliveira

submission deadline 31 May 2026 | 2 articles | Viewed by 5157 | Submission Open

Keywords: toxicology; chemical safety; emerging contaminants; integrated approaches; predictive modeling; new methodology approaches; high-throughput screening; adverse-outcome pathways; risk assessment; One Health

Application of In Vitro Toxicity Evaluation Models for Environmental Pollutants

edited by Leslimar Rios-Colon and Suzanne Compton Fitzpatrick

submission deadline 31 May 2026 | 1 articles | Viewed by 3086 | Submission Open

Keywords: in vitro techniques; environmental contaminants; new approach methodologies (NAMSs); per- and polyfluoroalkyl substances (PFASs); microplastics; pesticides; endocrine-disrupting chemicals; complex in vitro models

Air Pollution Monitoring and Epidemiology

edited by Liqiong Guo

submission deadline 31 May 2026 | Viewed by 466 | Submission Open

Keywords: air pollution monitoring; environmental epidemiology; health risk; exposure assessment; public health

Mapping Heavy Metal Exposure in the Exposome Era: Toxicological and Health Perspectives

edited by

Xiaojia He

and Matthew Smith

submission deadline 31 May 2026 | Viewed by 396 | Submission Open

Keywords: heavy metals; human health; risk assessment; exposure characterization; exposome; system toxicology; vulnerable populations; toxicological mechanisms

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Anthropogenic Soil Pollution: Analysis and Mitigation

edited by

Sayed M. Hassan

and

Philip Riekenberg

submission deadline 31 May 2026 | Viewed by 326 | Submission Open

Keywords: anthropogenic soil pollution; heavy metals; instrumental analysis; soil mitigation; environmental analysis

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Developmental Toxicity Mechanism of Emerging Contaminants (ECs)

edited by Xiaoli Xie

submission deadline 31 May 2026 | Viewed by 221 | Submission Open

Keywords: developmental toxicity; emerging contaminants (ECs); endocrine disruption; oxidative stress; risk assessment

(This special issue belongs to the Section Emerging Contaminants)

Application of Mass Spectrometry in Screening and Tracing of Environmental Pollutants

edited by

Runzeng Liu

Xiaoyun Liu

and Xiaoxia Feng

submission deadline 31 May 2026 | Viewed by 213 | Submission Open

Keywords: mass spectrometry; emerging pollutants; targeted screening; source apportionment; high-resolution mass spectrometry; pollutant tracing

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Fish Physiological Responses to Environmental Stressors

edited by

Jun Wang

submission deadline 5 Jun 2026 | 4 articles | Viewed by 5313 | Submission Open

Keywords: fish ecotoxicology; physiological disruption; oxidative stress biomarkers; ecological risk assessment; bioaccumulation dynamics; endocrine disruption; population changes

(This special issue belongs to the Section Ecotoxicology)

Adsorption and Photocatalysis of Organic Pollutants: Latest Advances and Prospects

edited by Yufeng Jiang

submission deadline 5 Jun 2026 | 2 articles | Viewed by 1824 | Submission Open

Keywords: emerging contaminants; adsorption; photocatalysis; soil and water; environmental remediation; degradation pathways; eco-toxicity

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Emerging Pollutants in the Aquatic Ecosystems: Occurrence, Fate and Effects on the Dissemination of Antibiotic Resistance Genes

edited by Lijun Zhou and Liangying He

submission deadline 10 Jun 2026 | Viewed by 461 | Submission Open

Keywords: antibiotics; antibiotic resistance genes; emerging pollutant; PPCPs; biocides; occurrence; ecological risk; horizontal gene transfer

(This special issue belongs to the Section Emerging Contaminants)

Novel Algorithms and Models in Computational Toxicology and Pollution: Towards More Accurate Toxicity and Pollution Prediction

edited by

Abdullahi Garba Usman

submission deadline 10 Jun 2026 | Viewed by 368 | Submission Open

Keywords: pollution; prediction; toxicology; environmental modelling; contaminants; novel computational techniques; remediation

(This special issue belongs to the Section Emerging Contaminants)

Physical and Chemical Treatment Techniques of Toxic Contaminants

edited by

Lei Xu

and

Jianbiao Peng

submission deadline 11 Jun 2026 | Viewed by 264 | Submission Open

Keywords: soil; sediment; atmosphere; water; toxic contaminants; environmental toxicology; ecotoxicology; physical remediation techniques; chemical remediation techniques; remediation assessment

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Nano-Toxicity: Exploring the Ecotoxicological Impacts of Nanoparticles and Combined Exposures

edited by

Juan Wang

and

Gang Liang

submission deadline 12 Jun 2026 | 1 articles | Viewed by 1575 | Submission Open

Keywords: ecotoxicology; environmental toxicology; biological effects; nanoparticles; microplastics

(This special issue belongs to the Section Ecotoxicology)

Computational and Experimental Insights into Transformation of Environmental Pollutants

edited by Li Ji,

Dong-Xing Guan

and

Piotr Paneth

submission deadline 15 Jun 2026 | 1 articles | Viewed by 1877 | Submission Open

Keywords: pollutant transformation; reaction mechanism; kinetic isotope effects (KIE); computational toxicology; biotransformation; human health-risk assessment; transformation products; machine learning; environmental fate; emerging contaminants

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Environmental Toxicants in Human Health: Oxidative Stress, Metabolism and Toxicity

edited by

David A. Lawrence

and Michael Lynes

submission deadline 15 Jun 2026 | 1 articles | Viewed by 963 | Submission Open

Keywords: environmental toxicants; immune cells; inflammation; oxidative stress; developmental and aging; autoimmunity

(This special issue belongs to the Section Human Toxicology and Epidemiology)

From Low-Tier to Individual Effects of Emerging Pollutants: Integrative Approaches to Ecotoxicological Assessments—2nd Edition

edited by

Tiago Simoes

Hugo Monteiro

and

Nuno Ferreira

submission deadline 18 Jun 2026 | 2 articles | Viewed by 3584 | Submission Open

Keywords: biomarkers; ecotoxicology; emerging pollutants; biological effects; mode of action; integrative analysis; analytical methods; sub-lethal endpoints

(This special issue belongs to the Section Ecotoxicology)

Safety Assessment of Toxic Substances in Food Contact Materials

edited by Emma Di Consiglio

submission deadline 19 Jun 2026 | Viewed by 250 | Submission Open

Keywords: toxicology; next-generation risk assessment; new approach methodologies (NAM); human health; food contact materials; environmental contaminants; toxicokinetics

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Advanced Hybrid and Electrochemical Techniques for Emerging Water Pollutants

edited by

Artur J. Motheo

and

Michel Zampieri Fidelis

submission deadline 20 Jun 2026 | Viewed by 316 | Submission Open

Keywords: electrochemical oxidation (EO); contaminants of emerging concern (CECs); nanomaterials; water treatment; nanostructured electrodes; nanotechnology; environmental toxicology; wastewater remediation; metal– organic frameworks (MOFs); hybrid catalysts; electrochemical oxidation (EO)

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Halogenated and Heterocyclic Derivatives of Polycyclic Aromatic Compounds (PACs): Bridging the Gaps in Occurrence, Exposure, and Toxicological Risk

edited by Philippe J. Thomas and

Gregg Tomy

submission deadline 20 Jun 2026 | Viewed by 240 | Submission Open

Keywords: polycyclic aromatic compounds (PACs); emerging contaminants; non-target screening; persistent organic pollutants (POPs); toxicology; bioaccumulation; source apportionment

(This special issue belongs to the Section Emerging Contaminants)

Advanced Electrochemical Oxidation Processes for Emerging Contaminant Treatment

edited by María Teresa Montañés Sanjuan

submission deadline 20 Jun 2026 | Viewed by 168 | Submission Open

Keywords: advanced electrochemical oxidation process (AEOP); electrooxidation; photoelectrooxidation; emerging anodes; wastewater treatment; emerging contaminants reduction; micropollutants reduction; toxicity reduction; environmental remediation

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Toxicity and Safety Assessment of Exposure to Heavy Metals

edited by

Cristina Carvalho

and

Michael Aschner

submission deadline 21 Jun 2026 | 8 articles | Viewed by 16162 | Submission Open

Keywords: human exposure to metals; environmental contamination; metals’ biogeochemistry; food metal contaminants; toxic effects of metals; metals’ mechanisms of toxicity; risk assessment; biomarkers; metallodrugs; metal ion chelators

(This special issue belongs to the Section Metals and Radioactive Substances)

Toxic Effects of Emerging Pollutants on Aquatic Organisms and Human

edited by

Christopher Martyniuk

submission deadline 23 Jun 2026 | 2 articles | Viewed by 2507 | Submission Open

Keywords: emerging contaminants; aquatics; human; molecular; biochemical; behavioral

(This special issue belongs to the Section Emerging Contaminants)

Airway Exposure to Pollution from Ambient Particulate Matter (PM) and Health Effects

edited by

Gloria Melzi

and

Yuewei Liu

submission deadline 26 Jun 2026 | 6 articles | Viewed by 9925 | Submission Open

Keywords: air pollution; particulate matter (PM); respiratory health; airway inflammation; oxidative stress; in vitro toxicology; alternative testing methods; cell culture models; health risk assessment

(This special issue belongs to the Section Air Pollution and Health)

Health Risk Assessment for Food Contaminants: Exposure and Human Toxicology

edited by

Yu-Syuan Luo

and

Nan-Hung Hsieh

submission deadline 26 Jun 2026 | 1 articles | Viewed by 3236 | Submission Open

Keywords: food contaminants; health risk assessment; exposure modeling; toxicology; new approach methodologies (NAMs)

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

New Approach Methodologies in Environmental Risk Assessment of Chemical Contaminants

edited by

Carlos Barata

submission deadline 26 Jun 2026 | 2 articles | Viewed by 3172 | Submission Open

Keywords: approaches for pollution assessment; ecotoxicology; ecological effects; new approach methodologies; chemical toxicity; chemical contaminants; risk assessment

(This special issue belongs to the Section Ecotoxicology)

Antibiotics and Resistance Genes in Environment

edited by

Fengxia Yang

and Shimei Zheng

submission deadline 30 Jun 2026 | 5 articles | Viewed by 17009 | Submission Open

Keywords: antibiotics; antibiotic resistance genes; environmental fate; human health; ecosystem impact; risk assessment; mitigation strategies

(This special issue belongs to the Section Emerging Contaminants)

Identification of Emerging Pollutants and Human Exposure

edited by

Xiaotu Liu

and

Ting Wu

submission deadline 30 Jun 2026 | 6 articles | Viewed by 16652 | Submission Open

Keywords: emerging contaminants; remediation strategies; non-targeted analysis; biomonitoring; exposome; risk assessment

The Neuroexposome: Integrating Exposures with Physiology to Understand Brain Health and Disease

edited by Megan Mahoney and

Jennifer L. Freeman

submission deadline 30 Jun 2026 | 3 articles | Viewed by 8584 | Submission Open

Keywords: exposome; exposomics; neuroexposome; neurodegeneration; neurotoxicology; neurodevelopment; developmental origins of health and disease (DOHAD)

(This special issue belongs to the Section Neurotoxicity)

Soil Heavy Metal Pollution and Human Health

edited by

Ping Xiang

and Chengchen Wang

submission deadline 30 Jun 2026 | 6 articles | Viewed by 8069 | Submission Open

Keywords: heavy metals; human health; food safety; monitoring techniques; pretreatment methods; contaminant control approaches

(This special issue belongs to the Section Metals and Radioactive Substances)

Impact of Pollutants on Aquatic Ecosystems and Food Safety

edited by Francesca Falco

submission deadline 30 Jun 2026 | 4 articles | Viewed by 7729 | Submission Open

Keywords: multi-stress; enviromental biodiversity; cascading effect; emerging contaminants; ecotoxicology; biomarkers

(This special issue belongs to the Section Emerging Contaminants)

Applicability of New Approach Methodologies (NAMs) to Skin Sensitization: Insights from Industry and Regulatory Perspectives

edited by Gertrude-Emilia Costin and Argel Islas-Robles

submission deadline 30 Jun 2026 | 4 articles | Viewed by 7471 | Submission Open

Keywords: skin sensitization; allergic contact dermatitis; new approach methodologies; regulatory testing; defined approaches; adverse outcome pathway; cosmetic industry; medical devices; mixtures; botanicals

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Multi-Media Exposure to Emerging Contaminants and Health Effects Across Physiological Systems: Exposure Pathways, Risk Assessment and Public Health Implications

edited by

Guanghui Dong

and

Lizi Lin

submission deadline 30 Jun 2026 | 6 articles | Viewed by 6246 | Submission Open

Keywords: emerging contaminants; multi-media exposure; exposure pathways; health effects; risk assessment; toxicity mechanisms; public health implications

(This special issue belongs to the Section Emerging Contaminants)

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