Reproductive Toxicity of Exposure to Endocrine Disruptors

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Reproductive and Developmental Toxicity".

Deadline for manuscript submissions: 31 October 2026 | Viewed by 258

Special Issue Editors


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Guest Editor
Department of Physiology and Toxicology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland
Interests: pesticides; endocrine disruptors; environmental toxicology; reproductive disorders; myometrial contractions
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Physiology and Toxicology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland
Interests: environmental pollution; environmental toxicology; endocrine disruption; reproductive endocrinology; ecotoxicology; toxicity toxicology; cell biology; physiology; testosterone
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is my pleasure to introduce this Special Issue, titled "Reproductive Toxicity of Exposure to Endocrine Disruptors", which will be published in Toxics.

Endocrine-disrupting chemicals (EDCs), both synthetic and naturally occurring, pose a significant threat to reproductive health in animals and humans. They can be categorized into two distinct groups: natural and synthetic. The natural EDCs include plant-derived compounds and hormonally active mycotoxins, or their metabolites. In contrast, synthetic EDCs encompass a broad range of industrial, agricultural, and environmental chemicals that possess hormonal activity. Recent studies have indicated that even low-dose or mixture exposures have the potential to induce functional disruptions in the reproductive system. These disruptions may include alterations in hormone signaling, impaired gametogenesis, reduced fertility, pregnancy complications, and developmental effects in offspring.

The objective of this Special Issue is to furnish a comprehensive overview of EDC-induced reproductive dysfunction, encompassing the male and female reproductive systems, molecular and epigenetic mechanisms, receptor-mediated pathways, and mixture effects. Contributions to this volume will include in vitro, ex vivo, and animal studies, as well as reviews addressing environmental exposure, risk assessment, and predictive toxicology.

This Special Issue will enhance understanding of how endocrine disruptors, natural and synthetic, affect reproductive function and support evidence-based strategies for reproductive and environmental health protection. It will do this by bringing together original research and critical reviews from leading experts.

It is with great pleasure that we extend a cordial invitation to researchers specializing in the fields of reproductive biology, toxicology, endocrinology, and environmental sciences to submit their contributions.

Dr. Michał Hubert Wróbel
Dr. Jarosław J. Młynarczuk
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • endocrine-disrupting chemicals (EDCs)
  • reproductive system dysfunction
  • hormonal signaling disruption
  • fertility and reproductive performance
  • environmental toxicology
  • chemical mixture effects
  • molecular mechanisms
  • epigenetic regulation
  • environmental exposure
  • risk assessment

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Published Papers

This special issue is now open for submission.
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