Molecular Mechanisms of PFAS-Induced Toxicity and Carcinogenicity
A special issue of Toxics (ISSN 2305-6304).
Deadline for manuscript submissions: 31 January 2026 | Viewed by 21
Special Issue Editors
Interests: emerging contaminants; molecular toxicity; health risks; cardiovascular diseases; carcinogenicity
Interests: emerging contaminants; toxic mechanism; toxicity prediction; new methodological approach; developmental toxicity
Interests: environmental epidemiology; heavy metal mixture; PFAS; machine learning
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue focuses on the molecular pathways and mechanisms underlying the toxic and carcinogenic effects of per- and polyfluoroalkyl substances (PFASs). It aims to integrate recent advances in understanding how PFASs interact with biological systems, including studies on gene expression, signaling pathways, oxidative stress, lipid metabolism, and epigenetic modifications. The Special Issue will highlight interdisciplinary research combining toxicology, molecular biology, and omics technologies to provide a holistic view of PFASs' impacts on health and the environment. It will also address gaps in our current knowledge, such as the role of the gut microbiota and intergenerational effects. By situating these findings within the existing literature, the Special Issue will offer insights into risk assessment, mitigation strategies, and policy implications, ultimately contributing to global efforts to reduce PFASs exposure and protect public health.
Prof. Dr. Dan Xu
Prof. Dr. Wei Liu
Dr. Ang Li
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- PFASs
- molecular toxicology
- carcinogenicity
- oxidative stress
- epigenetic modifications
- lipid metabolism
- gut microbiota
- endocrine disruption
- environmental health
- risk assessment
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