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Functional Nucleic Acids in Biosensing: From Detection to Therapeutic Applications

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: 25 July 2025 | Viewed by 84

Special Issue Editor

School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China
Interests: biosensors; aptamers; DNAzymes; food safety; disease diagnostics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The role of nucleic acids extends well beyond their traditional function as genetic material. Functional nucleic acids (FNAs)—such as aptamers, DNAzymes, and ribozymes—have recently been identified for their high affinity and catalytic activity. These chemically stable, easily modifiable molecules are invaluable in biosensing, rapid detection, and therapeutic interventions.

This Special Issue highlights the latest advancements in using functional nucleic acids for biosensing applications. Topics include selecting FNAs, designing FNA-based sensors, and their potential in precision medicine. This collection aims to underscore the transformative potential of FNAs in diagnostics and therapy, paving the way for the next generation of biosensing platforms and molecular treatments.

Dr. Qinqin Hu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • aptamers
  • DNAzymes
  • ribozymes or riboswitches
  • biosensors
  • SELEX
  • diagnosis
  • therapy
  • biochemical analysis

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Published Papers

This special issue is now open for submission.
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