Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pharmaceutical Applications and Therapeutic Mechanisms of Substances from Plant Origin
edited by Iliya Zhelev Slavov, , and
submission deadline 31 Oct 2025 | Viewed by 154 | Submission Open
Keywords: natural substances; phytotherapy; phytochemistry; chromatography; pharmacokinetics; pharmacodynamics; drug delivery
(This special issue belongs to the Section Drug Targeting and Design)
Novel Approaches to Drug Delivery in Ophthalmic Disorders
edited by Letizia Pelusi and
submission deadline 31 Oct 2025 | Viewed by 141 | Submission Open
Keywords: eye diseases; ocular drug delivery; ocular barrier; conventional therapies; innovative technologies; nanoparticle carriers; injectable hydrogels; ocular implants; gene therapy in ophthalmology
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Technology and Preparation of Solid Dispersion for the Enhancement of Oral Bioavailability
edited by , Andreea Loredana Vonica-Tincu and
submission deadline 31 Oct 2025 | Viewed by 124 | Submission Open
Keywords: solid dispersions; poor water solubility; rational formulation design; enhancement of oral bioavailability; preparation technology
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Medical Applications of Chitosan Nanoparticles submission deadline 31 Oct 2025 | Viewed by 115 | Submission Open
Keywords: chitosan; chitosan-based nanoparticles; drug delivery; biopolymers; polysaccharide; biomaterials; health concerns
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Impacts of the Kallikrein–Kinin System in Cancer and Its Treatment: A Focus on Drug Delivery and Formulations
edited by Indiara Brusco and
submission deadline 31 Oct 2025 | Viewed by 108 | Submission Open
Keywords: cancer pathophysiology; cancer pain; adverse effects of chemotherapy; cancer-related pain mechanisms; tumor microenvironment; kininogens; kininases; kinin B1 and B2 receptors; anticancer treatment; kinin B1 and B2 receptor antagonists; drug delivery; drug formulations; nanoparticles; liposomes; polymeric micelles; prodrugs
(This special issue belongs to the Section Biologics and Biosimilars)
Inhaled Advances: Emerging Trends in Pulmonary Drug Delivery submission deadline 31 Oct 2025 | Viewed by 105 | Submission Open
Keywords: pulmonary drug delivery; microparticles; nanomedicines; infectious diseases; lung targeting
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Metal Complexes as Antimicrobial Agents: Pharmacokinetics and Drug Development Implications submission deadline 31 Oct 2025 | Viewed by 104 | Submission Open
Keywords: metal complexes; antimicrobial agents; drug development; therapeutic agents; pharmacokinetics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Nanotechnology-Driven Drug Repurposing: A Novel Strategy for Targeted Drug Delivery and Pharmacokinetic Enhancement submission deadline 31 Oct 2025 | Viewed by 101 | Submission Open
Keywords: nanotechnology; drug repurposing; targeted drug delivery; pharmacokinetics; nanocarriers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovative Modelling and Simulation Approaches in Pharmaceutical Process Engineering
edited by Claudia Cogné and
submission deadline 31 Oct 2025 | Viewed by 94 | Submission Open
Keywords: pharmaceutical process engineering; modelling and simulation; mechanistic modelling; digital twins; machine learning; process optimisation and intensification; quality by design (QbD); process analytical technology (PAT); predictive modelling; pharmaceutical manufacturing
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Medical Applications of Extracellular Vesicles submission deadline 31 Oct 2025 | Viewed by 84 | Submission Open
Keywords: extracelular vesicles; intercellular communication; EV characterization in health and disease; EV-based drug delivery systems; biomarkers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Lipid, Polymeric, and Albumin-Based Drug Delivery Systems
edited by and
submission deadline 31 Oct 2025 | Viewed by 65 | Submission Open
Keywords: nanoparticle; albumin nanoparticle; human serum albumin; polymeric nanoparticle; polymeric micelle; PLGA nanoparticle; lipid nanoparticle; liposome; nanomedicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Photodynamic Therapy for Dental Diseases
edited by Patricia Comeau
submission deadline 31 Oct 2025 | Viewed by 63 | Submission Open
Keywords: photodynamic therapy; biomaterials; nanoparticles; dental; bone tissue engineering; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advancing HIV Prevention and Treatment: Pharmacokinetics, Pharmacodynamics, Toxicokinetics, Formulation and Delivery of Antiretroviral Drugs
edited by Julie B. Dumond
submission deadline 31 Oct 2025 | Viewed by 60 | Submission Open
Keywords: long-acting injectable antiretrovirals; PK/PD modeling of antiretrovirals; predictions of HIV PrEP effectiveness; antiretroviral toxicokinetics; novel drug delivery systems; novel dosing strategies; HIV treatment or prevention therapeutics in development; clinical pharmacokinetic studies in key populations; HIV drug delivery innovations; mannose receptor-targeted delivery
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Design, Development and Biomedical Applications of Hyaluronic Acid-Based Drug and Gene Delivery Systems
edited by Cristina Casadidio and Alice Spadea
submission deadline 31 Oct 2025 | Viewed by 48 | Submission Open
Keywords: hyaluronic acid; targeted drug delivery; gene delivery; CD44; nucleic acid delivery; HA conjugates; nanoparticles personalized medicine
(This special issue belongs to the Section Gene and Cell Therapy)
PLGA Micro/Nanoparticles in Drug Delivery
edited by Ilaria Arduino and
submission deadline 10 Nov 2025 | 2 articles | Viewed by 2237 | Submission Open
Keywords: micro- and nanotechnology; particle manufacturing; targeted delivery; particle characterization; biocompatibility; solubility enhancement
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Hepatic-Targeted Drug Delivery Systems submission deadline 10 Nov 2025 | Viewed by 785 | Submission Open
Keywords: hepatic drug delivery; phytotherapy; nanomedicine; lipid complexes; targeted therapies; liver diseases; drug vehicles; biomaterials; hepatocellular carcinoma; liposome; polymeric nanoparticles; lipid nanoparticles; hepatic stellate cell
(This special issue belongs to the Section Drug Targeting and Design)
Pathophysiological Influences on Pharmacokinetics and Pharmacodynamics
edited by Geraldo Duarte, Fernanda de Lima Moreira and Jhohann Richard de Lima Benzi
submission deadline 20 Nov 2025 | 2 articles | Viewed by 4187 | Submission Open
Keywords: drug– disease interactions; pharmacokinetics; pharmacodynamics; pharmacotherapy
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Novel Drug Delivery Systems for the Treatment of Skin Disorders submission deadline 20 Nov 2025 | 2 articles | Viewed by 2602 | Submission Open
Keywords: drug delivery; nanoparticles; vesicular systems; 3D-printed drugs; topical dosage form; skin disorder; penetration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanotechnology and RNA-Based Technologies Applied to Prophylaxis and Advanced Therapies
edited by and Vinicius Pinto Costa Rocha
submission deadline 20 Nov 2025 | 1 articles | Viewed by 2243 | Submission Open
Keywords: RNA-technologies; nanotechnology; messenger RNA (mRNA); interference RNA (RNAi); vaccines; treatment
(This special issue belongs to the Section Gene and Cell Therapy)
Long Acting Drug Delivery Formulations
edited by Thierry Vandamme
submission deadline 20 Nov 2025 | 1 articles | Viewed by 2109 | Submission Open
Keywords: improvement in patient adherence; steady state; drug bioavailability; reduced side effect; targeted delivery; long acting; sustained release; prolonged release; pulse release; compliance
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Biomaterials: Pharmaceutical Applications
edited by
submission deadline 20 Nov 2025 | 1 articles | Viewed by 747 | Submission Open
Keywords: natural biomaterials; synthetic biomaterials; drug delivery systems; tissue engineering; disease diagnosis; wound healing
(This special issue belongs to the Section Biopharmaceutics)
Recent Advances in Drug Formulation for Antiviral Therapy
edited by Chiara Medaglia
submission deadline 20 Nov 2025 | Viewed by 346 | Submission Open
Keywords: antiviral drugs development; infection; host-pathogen interactions; functional genomics
(This special issue belongs to the Section Drug Targeting and Design)
“The Power of Light” in Biomedical and Pharmaceutics: New Approaches for Photodynamic Purposes submission deadline 20 Nov 2025 | Viewed by 121 | Submission Open
Keywords: light; photosensitizers; photochemistry; photobiology; photodynamic therapy
(This special issue belongs to the Section Drug Targeting and Design)
Antibody–Drug Conjugates Therapeutics submission deadline 20 Nov 2025 | Viewed by 117 | Submission Open
Keywords: antibody– drug conjugate; drug delivery; antibody; payload; linker; protein conjugation
(This special issue belongs to the Section Biologics and Biosimilars)
Drug Product Performance: Bioavailability, Relative Bioavailability and Bioequivalence, 2nd Edition
edited by
submission deadline 30 Nov 2025 | 9 articles | Viewed by 12699 | Submission Open
Keywords: bioavailability; relative bioavailability; bioequivalence; biowaivers; statistical issues; regulatory issues; in vitro– in vivo correlations; physiologically-based biopharmaceutical models; physiologically-based pharmacokinetic models; qualification of models; population pharmacokinetic models; biopharmaceutical classification system; in vitro dissolution; dissolution metrics; predictive dissolution; clinical trial simulations; clinical trial optimization; healthy subjects in BA/BE trials; patients in BA/BE trials; pharmacokinetic parameters for BA/BE assessment; narrow therapeutic index drugs; highly variable drug products; immediate-release formulations; modified-release formulations; multiphasic drug products; extravascular routes of administration
(This special issue belongs to the Section Biopharmaceutics)
Inorganic Nanomaterials for the Development of Drug Delivery and Biomedical Applications
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 5621 | Submission Open
Keywords: inorganic nanoparticles; drug delivery; disease diagnosis; disease treatment; nano-biosensor; cancer theranostics; cancer imaging
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Drug Delivery Systems for the Treatment of Chronic Wound Healing
edited by Carolina Martinez and María Jimena Prieto
submission deadline 30 Nov 2025 | 5 articles | Viewed by 5607 | Submission Open
Keywords: wound healing; chronic diseases; wound repair and regeneration; drug delivery; topical formulations; biomaterial; nanotechnology; wound dressing; scar
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Hybrid Nanoparticles for Cancer Therapy
edited by Jacy Gameiro
submission deadline 30 Nov 2025 | 4 articles | Viewed by 3876 | Submission Open
Keywords: hybrid nanoparticles; cancer therapy; targeted drug delivery; nanomedicine; tumor microenvironment; gene therapy; immunotherapy; diagnostics; nanomaterials
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Naturally Derived Materials-Based Drug Delivery Systems and Their Biomedical Applications
edited by and
submission deadline 30 Nov 2025 | 3 articles | Viewed by 3010 | Submission Open
Keywords: naturally derived material; drug delivery systems; tissue engineering; regenerative medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Brain Tumors Treatment: Current and Future Challenges from Drug Formulations to Delivery Methods
edited by , Sara Badodi and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2944 | Submission Open
Keywords: blood– brain barrier pathophysiology in different tumors; pediatric brain tumors; adult brain tumors; considerations for adult vs. pediatric drug delivery development; nanocarriers and nanoparticles; focused ultrasound; convection enhanced delivery; intranasal delivery; intra-arterial delivery; combination strategies
(This special issue belongs to the Section Drug Targeting and Design)
Microneedles for Drug and Vaccine Delivery
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 2712 | Submission Open
Keywords: physical enhancement technologies; fabrication; characterization; applications; drug delivery; cosmetic applications; diagnostic; vaccination
(This special issue belongs to the Section Drug Delivery and Controlled Release)
In Silico Approaches of Drug–Target Interactions
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1334 | Submission Open
Keywords: in silico drug discovery; drug– target interactions; virtual screening; molecular modeling; machine learning in drug design; ADME predictions
(This special issue belongs to the Section Drug Targeting and Design)
Alternative Animal Models for Nanoparticle-Based Drug Delivery: Efficacy and Toxicity Assessment submission deadline 30 Nov 2025 | 1 articles | Viewed by 1149 | Submission Open
Keywords: alternative animal models; nanoparticle drug delivery; nanomedicine; toxicity assessment; bioavailability; in vivo models; biodistribution studies; therapeutic efficacy; pharmaceutical testing
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advancements and Innovations in Antibody Drug Conjugates
edited by , Shivaji Edupuganti and Ebaston Thankarajan
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1015 | Submission Open
Keywords: antibody– drug conjugates; monoclonal antibodies; targeted therapies; linker technologies; site-specific conjugation; bioimaging; pharmacokinetics; therapeutic index; next-generation ADCs; drug resistance; bispecific antibodies; combination therapies; off-target toxicity; efficacy and safety; tumor-specific antigens
(This special issue belongs to the Section Drug Targeting and Design)
Innovative Drug Delivery Systems: From Nanotechnology to Smart Devices
edited by Mahdi Ghavami and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1015 | Submission Open
Keywords: smart nanoparticles; innovative drug delivery; ingestible devices; targeted delivery systems; controlled release; microfabrication techniques; nano and microtechnology; biocompatible materials; bioavailability
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
In Vitro and In Vivo Biopharmaceutics Assessment of Silica-Based Drug Delivery Systems: Characterization, Drug Release, and Biological Performance submission deadline 30 Nov 2025 | 1 articles | Viewed by 857 | Submission Open
Keywords: drug delivery systems; mesoporous silica nanoparticles; biopharmaceutics evaluation; controlled drug release; drug release kinetics; in vivo performance; in vitro methodologies; pharmaceutical nanotechnology; stimuli-responsive systems; therapeutic efficacy
(This special issue belongs to the Section Biopharmaceutics)
Nanosystems for Advanced Diagnostics and Therapy submission deadline 30 Nov 2025 | 1 articles | Viewed by 681 | Submission Open
Keywords: nanosystems; theranostics; nanomedicine; molecular imaging; targeted drug delivery; radiolabeled nanoparticles; image guided therapy; smart nanocarriers; nanoradiopharmaceuticals; nanotechnology in diagnostics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Natural Compounds in Drug Delivery Systems submission deadline 30 Nov 2025 | 1 articles | Viewed by 658 | Submission Open
Keywords: natural products; extraction techniques; phytochemical analyses; natural compounds; biological active compounds; new formulations; encapsulated technics; biotechnology; drug delivery systems; bioavailability; pharmacy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovations in Advanced Drug Delivery Systems: Overcoming Challenges for Personalized Medicine
edited by Hélcio Silva Dos Santos
submission deadline 30 Nov 2025 | 1 articles | Viewed by 548 | Submission Open
Keywords: drug administration; polymers; structural characterization; nanoparticles; in silico studies; toxicity; bioavailability
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Carbon-Based Nanomaterials for Pharmaceutical Applications
edited by and Ivana Borišev
submission deadline 30 Nov 2025 | Viewed by 489 | Submission Open
Keywords: carbon-based nanomaterials; drug delivery; fullerenes; graphene; carbon nanotubes; nanodiamonds; carbon dots; biocompatibility; pharmaceutical applications
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Vaccine Delivery and Vaccine Administration submission deadline 30 Nov 2025 | 1 articles | Viewed by 417 | Submission Open
Keywords: vaccine delivery; vaccination; vaccine immunity; humoral immune response; cell-mediated immunity; infectious diseases; vaccine administration; novel routes of vaccination; nanoparticles
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Controlled Delivery of Cosmeceuticals Using Nanotechnology submission deadline 30 Nov 2025 | Viewed by 413 | Submission Open
Keywords: cosmeceuticals; skin; targeting; cosmetics; nanotechnology; delivery; formulation
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Therapeutic Drug Monitoring as a Useful Tool in Therapy Improvement, 3rd Edition submission deadline 30 Nov 2025 | 1 articles | Viewed by 353 | Submission Open
Keywords: drug– drug interactions; pharmacokinetics; therapeutic drug monitoring; machine learning
(This special issue belongs to the Section Clinical Pharmaceutics)
Advances in Solid and Semi-Solid Dosage Form Design for Enhanced Biopharmaceutical Performance submission deadline 30 Nov 2025 | Viewed by 325 | Submission Open
Keywords: solid dosage forms (tablets; capsules; pellets); novel formulation strategies; bioavailability enhancement; amorphous solid dispersions; lipid-based formulations; pharmaceutical cocrystals; excipient functionality and drug release; 3D printing in pharmaceuticals; hot melt extrusion (HME); spray drying in drug formulation; co-processing techniques; controlled and sustained drug release; targeted drug delivery systems; in vitro/in vivo correlation (IVIVC); quality-by-design (QbD) in pharmaceutics
(This special issue belongs to the Section Biopharmaceutics)
Nanoemulsions for Nose-to-Brain Drug Delivery
edited by Clóvis Orlando Pereira Da Fonseca and
submission deadline 30 Nov 2025 | Viewed by 304 | Submission Open
Keywords: nanoemulsion; intranasal; pharmacokinetics; nose-to-brain; neurology; olfactory; nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Developing Drug Delivery Approaches for Both Phage Therapeutics and Phage-Based Vectors
edited by and Daniel De Vos
submission deadline 30 Nov 2025 | Viewed by 290 | Submission Open
Keywords: phage vector; drug delivery; phage therapy; phage technology
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Smart Drug Delivery Systems for Immunotherapeutic Agents submission deadline 30 Nov 2025 | Viewed by 263 | Submission Open
Keywords: immunotherapy; drug delivery systems; nanomedicine; targeted therapy; cancer immunotherapy; lipid nanoparticles; biomaterials; controlled rel ease; immunoengineering; translational medicine
(This special issue belongs to the Section Gene and Cell Therapy)
Metal Nanoparticles in Therapeutics: Pioneering Drug Delivery Systems and Tissue Engineering submission deadline 30 Nov 2025 | Viewed by 237 | Submission Open
Keywords: metal nanoparticles; drug delivery systems; tissue engineering; cancer therapy; nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advancing Block Co-Polymer Nanomedicines: Innovations in Effective Drug Delivery submission deadline 30 Nov 2025 | Viewed by 215 | Submission Open
Keywords: pluronic-based nanomedicines and hydrogels; gene delivery; advanced drug delivery systems; radiotherapy and photodynamic therapy; combination therapy; polymeric nanomedicines; immunotherapy; nanogels; small-molecule delivery systems; block co-polymers nanomedicines
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advanced Drug Delivery Systems for Natural Products submission deadline 30 Nov 2025 | Viewed by 173 | Submission Open
Keywords: natural products; advanced drug delivery systems; liposomes; niosomes; phytosomes; lipid nanoparticles; smart polymers; biodegradable nanoparticles; polymeric nanoparticles; drug carriers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
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