Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Biomaterials for Drug Delivery in Radiotherapy
edited by and Fleury Augustin Nsole Biteghe
submission deadline 30 Sep 2025 | Viewed by 64 | Submission Open
Keywords: biomaterials in radiation; radiation enhancers; hydrogel in radiation; drug delivery in radiation with biomaterials; biomaterial delivery for image enhancers; biomaterial delivery to reduce irradiation-related injury; other related to the theme of this special issue
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Antibiotic Drug Delivery Systems
edited by , and Jessica V. Moore
submission deadline 10 Oct 2025 | 1 articles | Viewed by 3607 | Submission Open
Keywords: antibiotic drug delivery; antimicrobial resistance; targeted drug carriers; nanoparticles; liposomes; prodrug systems; drug solubility and stability; synergistic approaches; biofilm targeting; host– pathogen interaction; personalized antibiotic therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Carbohydrate-Based Carriers for Drug Delivery, 2nd Edition submission deadline 10 Oct 2025 | 2 articles | Viewed by 3052 | Submission Open
Keywords: nanomaterials; drug delivery; release profile; polisaccharides; oligosaccharides; inclusion complexes; targeted therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Emerging Drugs and Formulations for Pain Treatment
edited by Hector Isaac Rocha-González and
submission deadline 10 Oct 2025 | 1 articles | Viewed by 1272 | Submission Open
Keywords: analgesia; experimental pain treatment; preclinical models; pharmacotherapeutic management of pain; new drugs in clinical trials; drug development; psychotropic drugs; natural compounds; neuropathic Pain; chronic pain; synthetic drugs; new formulations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Skin Care Products for Healthy and Diseased Skin
edited by Nina Dragićević
submission deadline 20 Oct 2025 | 12 articles | Viewed by 34626 | Submission Open
Keywords: skin care products; skin delivery; healthy skin; diseased skin; nanoparticle-based products; natural emulsifiers
(This special issue belongs to the Section Drug Targeting and Design)
Plant Extracts and Their Biomedical Applications submission deadline 20 Oct 2025 | 5 articles | Viewed by 9798 | Submission Open
Keywords: plant extracts/secondary metabolites; bee products; nanoparticle  drug  delivery  system; microencapsulation; biomedical applications
(This special issue belongs to the Section Drug Targeting and Design)
The Role of Free Radicals and Antioxidants in Drug Activation and Effectiveness in Different Biological Systems submission deadline 20 Oct 2025 | 2 articles | Viewed by 5839 | Submission Open
Keywords: reactive oxygen species; free radicals (superoxide and hydroxyl radicals); antioxidants; nanomaterials (micro-nano particles); drug activation; drug delivery; in vitro and in vivo studies; polymer and lipid systems; edible oils
(This special issue belongs to the Section Drug Targeting and Design)
Recent Advances in Adeno-Associated Virus-Mediated Gene Therapy and Vaccine Development submission deadline 20 Oct 2025 | 1 articles | Viewed by 2126 | Submission Open
Keywords: AAV; gene therapy; vaccines; infectious diseases; communicable diseases; genetic disorders; non-communicable diseases
(This special issue belongs to the Section Gene and Cell Therapy)
Pharmacy Compounding of Personalized Preparation for Specific Patients: Challenges and Advantages, 2nd Edition submission deadline 20 Oct 2025 | 1 articles | Viewed by 931 | Submission Open
Keywords: formulations; drug compounding; extemporaneous preparations; galenics; quality; standard operating procedures
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Methods of Potentially Improving Drug Permeation and Bioavailability
edited by Wihan Pheiffer, and
submission deadline 20 Oct 2025 | 1 articles | Viewed by 539 | Submission Open
Keywords: drug permeation; bioavailablity enhancement; drug delivery systems; biological barriers; formulation strategies; in vivo; ex vivo; pharmacokinetics
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Non-Viral Vaccine Delivery
edited by , and
submission deadline 20 Oct 2025 | Viewed by 206 | Submission Open
Keywords: vaccine delivery; adjuvant; nanoparticle; virus-like particle; emulsion; microneedle; laser; immunogenicity; vaccine safety; antigen uptake
(This special issue belongs to the Section Gene and Cell Therapy)
Targeted Drug Delivery: Innovations to Overcome Biological and Technical Barriers submission deadline 20 Oct 2025 | Viewed by 204 | Submission Open
Keywords: drug delivery; biological barriers; drug stability; patient compliance; resistance
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Functionalized Metal Nanoparticles in Cancer Therapy submission deadline 20 Oct 2025 | Viewed by 200 | Submission Open
Keywords: functionalized metal nanoparticles; cancer therapy; targeted drug delivery; photothermal therapy; tumor targeting; biocompatibility; nanomedicine; imaging agents; precision medicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Ionic Liquids in Pharmaceutical and Biomedical Applications, 2nd Edition
edited by
submission deadline 30 Oct 2025 | 4 articles | Viewed by 15542 | Submission Open
Keywords: ionic liquids; deep eutectic solvents; active pharmaceutical ingredients (API); drug delivery systems; antimicrobial properties; drug and protein stabilization; nanoformulations; biosensing
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Recent Advances in Peptide and Protein-Based Drug Delivery Systems
edited by
submission deadline 30 Oct 2025 | 2 articles | Viewed by 1719 | Submission Open
Keywords: drug delivery systems; protein; peptide; nanotechnology; targeted delivery; nanocomposites
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances on Molecular Modeling in Pharmaceutics submission deadline 30 Oct 2025 | 1 articles | Viewed by 818 | Submission Open
Keywords: DFT; quantum mechanics; molecular mechanics; quantum chemistry; molecular dynamics; adsorption simulations; molecular modeling; pharmacokinetics; biopharmaceutics
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Drug–Drug Interactions—New Perspectives submission deadline 30 Oct 2025 | Viewed by 89 | Submission Open
Keywords: safety of therapy; cytochrome P450; pharmacokinetics; contraindication; machine learning; metabolism
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Natural Pharmaceuticals Focused on Anti-inflammatory Activities submission deadline 31 Oct 2025 | 7 articles | Viewed by 14625 | Submission Open
Keywords: anti-inflammatory properties; chemical identification of natural anti-inflammatory agents; delivery and controlled-release systems; natural extracts; mechanisms of natural anti-inflammatory agents; molecular docking; natural products; plants and fungi; structure– effect relationships
(This special issue belongs to the Section Drug Targeting and Design)
Ophthalmic Drug Delivery, 3rd Edition submission deadline 31 Oct 2025 | 5 articles | Viewed by 11816 | Submission Open
Keywords: ocular pharmacokinetics; ocular drug delivery systems; ocular routs of drug administration; intravitreal administration; topical administration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Extemporaneous Formulations: Filling the Gap in the Pharmaceutical Industry with Personalized Medicines submission deadline 31 Oct 2025 | 9 articles | Viewed by 10921 | Submission Open
Keywords: extemporaneous; compounding; pharmaceutical; formulation; personalized; pharmacy
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Proteases and Serpins: Therapeutic Targets for Various Diseases
edited by
submission deadline 31 Oct 2025 | 5 articles | Viewed by 10587 | Submission Open
Keywords: serpin; protease; serine protease inhibitors; disease; cancer; diabetes; cardiovascular disease; inflammatory disease; therapy; drug development; oxidative stress
(This special issue belongs to the Section Drug Targeting and Design)
Novel Approaches in the Search for Active Compounds in Drug Discovery and Development submission deadline 31 Oct 2025 | 4 articles | Viewed by 8644 | Submission Open
Keywords: drug candidates; adjuvants; multidrug resistance; organic synthesis; ADMETox; cancer research; antimicrobial agents; immunology; novel approaches; drug discovery & development; transition metals; rare earth elements; selenium; tellurium; arsenic
(This special issue belongs to the Section Drug Targeting and Design)
Advanced Nanotechnology for Combination Therapy and Diagnosis
edited by Renato Sonchini Gonçalves and Gustavo Braga
submission deadline 31 Oct 2025 | 4 articles | Viewed by 6742 | Submission Open
Keywords: nanotechnology; nanomedicine; combination therapy; noncommunicable diseases; theranostics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Aspects and Implementation of Pharmaceutical Quality by Design, 2nd Edition submission deadline 31 Oct 2025 | 4 articles | Viewed by 5758 | Submission Open
Keywords: quality by design; identification of patient needs; process optimization; design of experiments; multivariate data analysis; machine learning; process analytical technologies; control strategy
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advanced Drug Delivery Across the Blood–Brain Barrier
edited by and Zhen Zhao
submission deadline 31 Oct 2025 | 2 articles | Viewed by 5121 | Submission Open
Keywords: blood– brain barrier (BBB); central nervous system (CNS); drug delivery; neurological disease; nanotechnology; transport mechanism; targeted delivery; BBB permeability; glioblastoma
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Analysis and Modeling of Solid Drug Product submission deadline 31 Oct 2025 | 3 articles | Viewed by 2381 | Submission Open
Keywords: design-of-experiments (DoE); data-driven modeling/analysis; mechanistic modeling; hybrid modeling; uncertainty analysis; real-time monitoring/release testing; digitalization
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advanced In Silico Methods and Digital Platforms for the Prediction of ADMET and Pharmacokinetics Properties submission deadline 31 Oct 2025 | 1 articles | Viewed by 2229 | Submission Open
Keywords: ADMET properties prediction; physiologically based pharmacokinetic (PBPK) modeling; in silico digital platform; chemoinformatics; computer-aided drug discovery; predictive toxicology
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Protein-Based Nanoparticles: Promising Platforms for Drug Delivery
edited by Cheng Cao and Jiali Zhai
submission deadline 31 Oct 2025 | 1 articles | Viewed by 2140 | Submission Open
Keywords: nanoparticles; protein corona; drug delivery; protein interactions; cellular uptake; physicochemical properties; characterizations
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Application of Phytochemicals in Innovative Drug Delivery Systems and Formulations submission deadline 31 Oct 2025 | 1 articles | Viewed by 1461 | Submission Open
Keywords: microparticles; nanoparticles; drug delivery systems; cancer; inflammation; phytochemicals; phytotherapy; medicinal plants
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Natural Bioactive Compounds in Micro- and Nanocarriers
edited by , and Ivana Nešić
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1293 | Submission Open
Keywords: phytochemicals; natural compound; natural products; development of micro- and nano-sized delivery systems; formulation of products based on nano- and micro-systems; systems for targeted delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Essential Oils: From Biological Activity to Pharmaceutical Applications submission deadline 31 Oct 2025 | 1 articles | Viewed by 579 | Submission Open
Keywords: EOs as active chemicals; EOs’ biological activity (antimicrobial; insecticidal; herbicidal; bactericidal; and fungicidal properties); EOs encapsulation procedures; EOs for improving human health; EOs in active packaging products; polymeric networks for EOs encapsulation
(This special issue belongs to the Section Drug Targeting and Design)
Impact of Lipid Nanoparticle Physicochemical Properties on mRNA Vaccine
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 451 | Submission Open
Keywords: lipid nanoparticle formulation; ionizable lipids design; delivery of mRNA vaccines; sustained/controlled release; targeted delivery; stability and storage solutions; pharmacokinetics and pharmacodynamics
(This special issue belongs to the Section Gene and Cell Therapy)
Innovations in Drug Delivery, Pharmacometrics, and Clinical Studies in Veterinary Medicine submission deadline 31 Oct 2025 | Viewed by 327 | Submission Open
Keywords: veterinary medicine; pharmacometrics; PK/PD modeling; drug delivery; dose optimization
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Smart Polymeric Nanoparticle-Based Drug Delivery Systems
edited by Amos O. Abioye
submission deadline 31 Oct 2025 | Viewed by 322 | Submission Open
Keywords: polymer therapeutics; polymeric nanocarriers; polymer– drug conjugates; smart drug delivery systems; precision-driven drug targeting; functionalized polymers; polymeric self-assembly; quality by design approaches; process optimization techniques; therapeutic efficacy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Anticancer Drug Metabolism Research: Implications for Personalized Therapeutics submission deadline 31 Oct 2025 | Viewed by 277 | Submission Open
Keywords: anticancer drug metabolism; personalized medicine; drug interactions; therapeutic efficacy; drug safety; pharmacogenomics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Nanotechnology in Formulation of Tumor-Targeted Drug Delivery Systems submission deadline 31 Oct 2025 | Viewed by 187 | Submission Open
Keywords: nanotechnology; formulations; tumor and cancer treatment; drug delivery
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advanced Nano-Based Drug Delivery Systems for Infectious Diseases
edited by Claudio J. Salomon and Maria Celina Lamas
submission deadline 31 Oct 2025 | Viewed by 173 | Submission Open
Keywords: nanomedicines; infectious disease; microorganisms; therapeutic treatments; drug delivery systems
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Pharmaceutical Applications and Therapeutic Mechanisms of Substances from Plant Origin
edited by Iliya Zhelev Slavov, , and
submission deadline 31 Oct 2025 | Viewed by 143 | Submission Open
Keywords: natural substances; phytotherapy; phytochemistry; chromatography; pharmacokinetics; pharmacodynamics; drug delivery
(This special issue belongs to the Section Drug Targeting and Design)
Novel Approaches to Drug Delivery in Ophthalmic Disorders
edited by Letizia Pelusi and
submission deadline 31 Oct 2025 | Viewed by 139 | Submission Open
Keywords: eye diseases; ocular drug delivery; ocular barrier; conventional therapies; innovative technologies; nanoparticle carriers; injectable hydrogels; ocular implants; gene therapy in ophthalmology
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Technology and Preparation of Solid Dispersion for the Enhancement of Oral Bioavailability
edited by , Andreea Loredana Vonica-Tincu and
submission deadline 31 Oct 2025 | Viewed by 122 | Submission Open
Keywords: solid dispersions; poor water solubility; rational formulation design; enhancement of oral bioavailability; preparation technology
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Quality by Design in Pharmaceutical Manufacturing submission deadline 31 Oct 2025 | Viewed by 120 | Submission Open
Keywords: quality by design; critical quality attributes; pharmaceutical technology; drug product process development; process analytical technologies; patient-centric approaches; process validation; ongoing procedure performance verification; analytical quality by design; continuous manufacturing; design of experiments; clinically relevant specification; risk assessment
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Medical Applications of Chitosan Nanoparticles submission deadline 31 Oct 2025 | Viewed by 111 | Submission Open
Keywords: chitosan; chitosan-based nanoparticles; drug delivery; biopolymers; polysaccharide; biomaterials; health concerns
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Impacts of the Kallikrein–Kinin System in Cancer and Its Treatment: A Focus on Drug Delivery and Formulations
edited by Indiara Brusco and
submission deadline 31 Oct 2025 | Viewed by 101 | Submission Open
Keywords: cancer pathophysiology; cancer pain; adverse effects of chemotherapy; cancer-related pain mechanisms; tumor microenvironment; kininogens; kininases; kinin B1 and B2 receptors; anticancer treatment; kinin B1 and B2 receptor antagonists; drug delivery; drug formulations; nanoparticles; liposomes; polymeric micelles; prodrugs
(This special issue belongs to the Section Biologics and Biosimilars)
Metal Complexes as Antimicrobial Agents: Pharmacokinetics and Drug Development Implications submission deadline 31 Oct 2025 | Viewed by 100 | Submission Open
Keywords: metal complexes; antimicrobial agents; drug development; therapeutic agents; pharmacokinetics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Nanotechnology-Driven Drug Repurposing: A Novel Strategy for Targeted Drug Delivery and Pharmacokinetic Enhancement submission deadline 31 Oct 2025 | Viewed by 98 | Submission Open
Keywords: nanotechnology; drug repurposing; targeted drug delivery; pharmacokinetics; nanocarriers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Inhaled Advances: Emerging Trends in Pulmonary Drug Delivery submission deadline 31 Oct 2025 | Viewed by 91 | Submission Open
Keywords: pulmonary drug delivery; microparticles; nanomedicines; infectious diseases; lung targeting
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovative Modelling and Simulation Approaches in Pharmaceutical Process Engineering
edited by Claudia Cogné and
submission deadline 31 Oct 2025 | Viewed by 88 | Submission Open
Keywords: pharmaceutical process engineering; modelling and simulation; mechanistic modelling; digital twins; machine learning; process optimisation and intensification; quality by design (QbD); process analytical technology (PAT); predictive modelling; pharmaceutical manufacturing
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Medical Applications of Extracellular Vesicles submission deadline 31 Oct 2025 | Viewed by 79 | Submission Open
Keywords: extracelular vesicles; intercellular communication; EV characterization in health and disease; EV-based drug delivery systems; biomarkers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Lipid, Polymeric, and Albumin-Based Drug Delivery Systems
edited by and
submission deadline 31 Oct 2025 | Viewed by 64 | Submission Open
Keywords: nanoparticle; albumin nanoparticle; human serum albumin; polymeric nanoparticle; polymeric micelle; PLGA nanoparticle; lipid nanoparticle; liposome; nanomedicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Photodynamic Therapy for Dental Diseases
edited by Patricia Comeau
submission deadline 31 Oct 2025 | Viewed by 60 | Submission Open
Keywords: photodynamic therapy; biomaterials; nanoparticles; dental; bone tissue engineering; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
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