Medical Applications of Extracellular Vesicles

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 35

Special Issue Editors


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Guest Editor
Departamento de Bioquímica Clínica e Inmunología, Facultad de Farmacia, Universidad de Concepción, Concepción 4030000, Chile
Interests: lipid metabolism disorders; endothelial progenitor cells; vascular repair

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Guest Editor
Departamento de Bioquímica Clínica e Inmunología, Facultad de Farmacia, Universidad de Concepción, Concepción 4030000, Chile
Interests: biomarkers; regeneration; exosome

Special Issue Information

Dear Colleagues,

Extracellular vesicles (EVs) are a heterogeneous group of membrane-bound structures, including exosomes, microvesicles, and apoptotic bodies, that play a crucial role in intercellular communication. Although EVs were initially thought to be primarily cellular waste disposal systems, they are now recognized as crucial mediators of numerous physiological and pathophysiological processes due to their cargo that includes proteins, lipids, and nucleic acids. The role of EVs in the pathogenesis of various diseases, as well as their potential application in diagnosis and treatment, has generated growing interest in their clinical applications.

This Special Issue aims to explore the medical applications of EVs, focusing on their potential use as biomarkers, therapeutic agents, and drug delivery systems. We invite submissions of original research and reviews addressing EV isolation and characterization techniques, their role in immune modulation, and innovative strategies for their engineering and targeted delivery. Special attention will be paid to translational challenges, including regulatory aspects and scalability for clinical use.

Along with contributions from experts in the field, we hope this Special Issue will provide a comprehensive and up-to-date overview of the medical applications of extracellular vesicles. We also seek to encourage interdisciplinary collaboration and promote the clinical application of EV-based technologies, contributing to the advancement of precision medicine. We invite researchers and clinicians to submit their work and be part of this rapidly evolving field.

Prof. Dr. Claudia Radojkovic
Dr. Claudio Aguayo
Guest Editors

Manuscript Submission Information

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Keywords

  • extracelular vesicles
  • intercellular communication
  • EV characterization in health and disease
  • EV-based drug delivery systems
  • biomarkers

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Published Papers

This special issue is now open for submission.
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