Cyclodextrins and Their Inclusion Complexes for Pharmaceutical Uses
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 32133
Special Issue Editors
Interests: cyclodextrin; polymer; electrospinning; chromism; hybrid materials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cyclodextrins comprise a family of compounds structured by (α-1,4) glucopyranose units with a hydrophilic outer surface and hydrophobic cavity. Being one of the most versatile molecules in pharmaceutical technology, cyclodextrins are capable of forming inclusion complexes with a variety of guest molecules. Moreover, cyclodextrins are also a prominent subject in different research areas, especially chemistry, pharmaceutics, and pharmacology. Structured by non-covalent interaction, the host–guest supramolecular systems have been used in pharmaceutical formulations since 1970. Therefore, understanding supramolecular structures interactions, including physical and chemical parameters of the host–guest systems, are crucial when analyzing in vitro and in vivo data from the superstructures compared to the free drug molecules. Among many drug molecules properties that can be modified by cyclodextrins, the most common pharmaceutical applications are to enhance drug solubility, stability, and bioavailability. This Special Issue will collect researches covering physical and/or chemical characterization (by experimental and computational findings) of cyclodextrins inclusion complexes and their uses in the pharmaceutical and biomedical application topics.
Prof. Dr. Frederico De Sousa
Prof. Dr. Juliana Fedoce Lopes
Guest Editors
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Keywords
- cyclodextrin
- cyclodextrin polymers
- inclusion complexes
- characterization
- physical–chemical characterization
- computational chemistry
- supramolecular structure
- host–guest interaction
- drug release
- in vitro and/or in vivo studies
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