Antifungal and Antiparasitic Drug Delivery Volume II

Dear Colleagues,

Fungal and parasitic diseases affect more than a billion people across the globe, one-sixth of the world´s population, mostly located in developing countries. The lack of effective and safer treatments combined with a deficient diagnosis lead to serious chronic illness or even death. There is a mismatch between the rate of drug resistance and the development of new medicines. Formulation of antifungal and antiparasitic drugs adapted to different administration routes is challenging bearing in mind their poor water solubility, which limits their bioavailability and efficacy. Hence, there is an unmet clinical need to develop vaccines and novel formulations and drug delivery strategies that can improve the bioavailability and therapeutic effect by enhancing their dissolution, increasing their chemical potency, stabilising the drug and targeting high concentration of drug to the infection sites. In this issue, an update on novel drug delivery strategies of antifungal and antiparasitic drugs to treat both topical and systemic infections will be discussed.

Prof. Dr. Juan José Torrado Durán
Prof. Dr. Dolores R. Serrano
Dr. Javier Capilla
Guest Editors

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