Application of Nanocarrier Systems for the Delivery of Bioactive Natural Products and Derivatives Thereof
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (20 November 2024) | Viewed by 5019
Special Issue Editors
2. Institute of Chemistry and Metabolism of Drugs (IQUIMEFA), University of Buenos Aires—National Scientific and Technical Research Council, Buenos Aires, Argentina
Interests: neglected diseases; antimicrobial activity; natural compounds; plant extracts; terpenoids; flavonoids; Asteraceae
Special Issues, Collections and Topics in MDPI journals
2. IPLUSO/NICiTeS-ERISA-Escola Superior de Saúde Ribeiro Sanches, Rua do Telhal aos Olivais, 8-8ª, 1900-693 Lisboa, Portugal
Interests: natural products chemistry; structure-activity relationships
Interests: small organic molecules; natural products; anticancer and antibacterial agents; multitarget inhibitors; hybrids; bioconjugates
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Since ancient times, natural products have been used as medicines for the treatment of several illnesses. In this sense, the isolation and identification of bioactive natural compounds have played a crucial role in the drug discovery process.
Natural molecules as well as their derivatives have been used for the development of novel treatments for a variety of diseases, with cancer and infectious diseases being among the most noteworthy. Although bioactive natural compounds have many advantages, such as a low molecular weight, variety of structures and chiral centers that allow for interactions with biological targets, many of them also have drawbacks related to their poor solubility, permeability and/or stability in biological mediums.
At present, researchers are putting more efforts in developing a Novel Drug Delivery System (NDDS) for the effective and targeted delivery of old, well-established molecules to increase safety and efficacy and to reduce the needed dose, instead of inventing new drug molecules.
In recent years, nanotechnology has made great progress in the development of carriers for the transportation of drugs. These systems are especially of interest for natural compound delivery, since they can overcome their limitations by improving pharmacokinetic properties and the arrival to the site of action.
This Special Issue will cover aspects related to the application of nanotechnology systems for the delivery of natural products as potential therapeutic treatments for acute and chronic diseases. Submissions, including research papers as well as mini-reviews and review articles, will be considered.
Prof. Dr. Valeria Patricia Sülsen
Prof. Dr. Maria Do Céu Costa
Prof. Dr. Constantinos Athanassopoulos
Guest Editors
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Keywords
- nanotechnology
- nanocarriers
- natural compounds
- novel drug delivery (NDDS)
- target delivery
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