Current Research in Drug Metabolism and Drug–Drug Interactions (DDIs)
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics".
Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 1724
Special Issue Editor
Interests: in vitro early ADME models; CNS and ophthalmic drug permeability; eye drop formulas; drug metabolism; rheology-mucoadhesivity correlation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
One of the most complex pharmacokinetic characteristics of drug research that covers the entire process is drug metabolism and the associated drug–drug interactions (DDIs). A repeated summary of the new research and development of the field is highly justified and helps the scientific community to identify new problems and outline possible solutions.
In accordance with the above, the Special Issue entitled “Current Research in Drug Metabolism and Drug-Drug Interactions (DDIs)” will consider for publication manuscripts describing the results of original basic and clinical research that contribute significant and novel information on the following topics:
- The metabolic studies of important existing drugs or known toxicants that address their potential clinical or translational significance;
- Novel in vivo, in vitro, ex vivo, or in silico model systems for drug metabolism and DDIs, such as 3-D culture, stem cells, and liver-on-a-chip systems;
- Novel analytical technologies and toolboxes that can be broadly applied to the study of drug metabolism and DDIs;
- The mechanistic aspects of drug metabolism and DDIs, including the structural studies of formed (reactive) metabolites, enzymes, and transporters and the biochemical studies of nuclear receptors that regulate drug metabolism;
- The impact of drug metabolism on pharmacokinetics, pharmacodynamics, or drug adverse effects, such as DDIs;
- The studies of drug metabolism by microbiome or other non-animal species offer new insights into the biological fate of drugs or other xenobiotics in living systems.
I look forward to receiving your contributions.
Prof. Dr. György T. Balogh
Guest Editor
Manuscript Submission Information
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Keywords
- pharmacokinetic
- drug metabolism
- drug–drug interactions (DDIs)
- pharmacodynamics
- drug adverse
- in vivo
- in vitro
- stem cells
- liver-on-a-chip
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