Special Issue "Novel Approaches for Optimizing Pharmacotherapy Based on Recent Pharmacokinetic, Pharmacodynamic, and Pharmacogenetic Developments"

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics".

Deadline for manuscript submissions: 20 December 2023 | Viewed by 275

Special Issue Editors

Department of Pharmacokinetics and Physical Pharmacy, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland
Interests: pharmacokinetics; pharmacodynamics; PK/PD modeling; PBPK modeling; bioanalysis; PDE inhibitors; inflammation
Department of Pharmacokinetics and Physical Pharmacy, Jagiellonian University Medical College, Medyczna 9, PL 30-688 Cracow, Poland
Interests: preclinical pharmacokinetic assessment of pharmacologically active compounds; estimation of hepatic clearance; isolated hepatocytes; isolated perfused liver model; bioanalysis; LC-MS/MS; drug–drug interactions; clinical pharmacokinetics of cytostatic and antimicrobial drugs
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Special Issue Information

Dear Colleagues,

Drug development is a complex, costly, and time-consuming process. Even if the number of new drugs approved each year is increasing, slow progress is observed in approval of drugs for some disorders, such as neurological or lifestyle diseases, with greater emphasis being placed on anticancer drugs and biologics. Therefore, we should adopt the most effective use of existing drugs supported by innovative analytical, computational, and genetic-based methods.

This Special Issue presents the advances in the optimization of pharmacotherapy observed in recent years as a result of the current progress in pharmacokinetics and pharmacodynamics, the introduction of new sampling and analytical techniques, and the implementation of pharmacogenetic testing in clinical practice. Equally important in this area is the introduction of novel biomarkers of drug response and disease progression, advanced computer-based methods, and PK/PD models that can be used to select an appropriate dose and dosage scheme for an individual patient.

Prof. Dr. Elżbieta Wyska
Dr. Małgorzata Szafarz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • dosage individualization
  • TDM
  • pharmacogenetics
  • PK/PD modeling
  • simulations
  • software
  • biomarkers

Published Papers

This special issue is now open for submission.
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