Development of Spray-Dried Powders for Pulmonary Drug Delivery

Dear Colleagues,

Spray drying represents an attractive method for engineering inhaled drug particles. It enables the production of particles with well-controlled size, shape, and density which are crucial for the effectiveness of particles’ aerosolization and lung deposition. Spray drying is also widely utilized to improve the solubility of poorly water-soluble drugs, produce inhaled fixed-dose combination powders, and transform nanoparticles into inhalable microparticles. Thus, the importance of spray drying lies not only in optimizing drug delivery efficiency but also in fostering innovation in pulmonary drug delivery of different therapeutics for the treatment of lung and systemic diseases.

This Special Issue aims to highlight current research in formulating inhalable dry powder using spray drying; exploring the complex effect of the processing and formulation factors on the physicochemical and aerosolization properties of the dried powder; the formulation of spray-dried fixed-dose drug combinations for inhalation; understanding the solid-state properties of multicomponent spray dried particles; and utilizing spray drying for formulating inhaled nanoparticles and biopharmaceuticals.

Dr. Nazrul Islam
Dr. Alhajj Nasser
Guest Editors

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