Design of Injectable and Self-Healing Hydrogels for Tissue Regeneration and Drug Delivery
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Biologics and Biosimilars".
Deadline for manuscript submissions: closed (15 February 2024) | Viewed by 4262
Special Issue Editors
Interests: biomaterials; drug delivery; cancer immunotherapy; photothermal therapy; tissue engineering
Special Issue Information
Dear Colleagues,
Injectable and self-healable hydrogels have shown great promise in tissue engineering and drug delivery because they have the capacity to provide mechanical support, cell adhesion sites, and the controlled release of therapeutic molecules at the site of the defect. In addition to the merit of mimicking the natural extracellular matrix of defect tissues, these hydrogels can also be delivered to various anatomical sites, including irregularly shaped or hard-to-reach areas without the need for open surgeries, leading to less trauma, faster recovery times, and lower risk of infection and complications.
This Special Issue aims to cover the most recent advances in injectable and self-healable hydrogels by discussing different fabrication strategies, available triggered drug release mechanisms, their potential for multimodal therapy and cell delivery, as well as challenges of optimal balance between gelation time, mechanical properties, and biodegradability to provide high flexibility in their biomedical application and make them a more promising tool for the future of regenerative medicine and drug delivery.
Dr. Mohammad-Ali Shahbazi
Dr. Yuan Xiong
Guest Editors
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Keywords
- nano-reinforced injectable hydrogel
- physically crosslinked hydrogel
- chemically crosslinked hydrogel
- photothermal hydrogel
- cell delivery
- controlled drug release
- pH responsive
- enzyme responsive
- temperature responsive
- wound healing
- bone repair
- combined therapy
- heart regeneration
- muscle regeneration
- cartilage repair
- theranostic hydrogel
- local therapy
- long-term drug release
- chemotherapy
- immunotherapeutic injectable hydrogel
- ultrasound-based therapy
- anti-inflammatory injectable hydrogel
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