Special Issue "Searching for New Therapeutic Targets with Anti-Obesity Potential"

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmacology".

Deadline for manuscript submissions: 31 May 2021.

Special Issue Editors

Dr. Magdalena Kotańska
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Guest Editor
Department of Pharmacological Screening, Jagiellonian University Medical College, 9 Medyczna Street, PL 30-688 Krakow, Poland
Interests: searching for new mechanisms of action of small molecules to reduce body mass, compensate for disorders of the circulatory system or level depression-like disorders; pharmacology developments towards new therapeutic approaches for obesity, diabetes and selected metabolic disorders, hypertension, atherosclerosis, depression; ligands of adrenergic, histamine, serotonin, adenosine, and cannabinoid receptors
Prof. Dr. Amélia Pilar Rauter
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Guest Editor
Departamento de Química e Bioquímica (DQB) e Centro de Química e Bioquímica (CQB), Faculdade de Ciências, Universidade de Lisboa (FCUL), Rua Ernesto de Vasconcelos, Campo Grande,Edifício C8, 5º Piso, 1749-016 Lisboa, Portugal
Interests: carbohydrate small molecule synthesis; organic and biomolecular chemistry developments towards new therapeutic approaches for diabetes; Alzheimer’s disease and other amyloid diseases and carbohydrate-based antibiotics
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Dr. Małgorzata Szafarz
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Guest Editor
Department of Pharmacokinetics and Physical Pharmacy, Jagiellonian University Medical College, Krakow, Poland
Interests: pharmacokinetic studies of novel; pharmacologically active chemical compounds; potential drugs; estimation of hepatic clearance of drugs using isolated hepatocytes and IPL (isolated perfused liver) models; development and validation of analytical methods for the purpose of pharmacokinetic analysis using high performance liquid chromatography combined with mass spectrometry; clinical pharmacokinetics of cytostatic and antimicrobial drugs
Dr. Monika Kubacka
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Guest Editor
Department of Pharmacodynamics, Jagiellonian University Medical College, 9 Medyczna Street, PL 30-688 Krakow, Poland
Interests: searching for new mechanisms of action of small molecules to treat hypertension and metabolic syndrome; inflammation and insulin signaling, obesity; adipose tissue, endothelial integrity; endothelial dysfunction, arterioscerosis; platelet aggregation, ligands of adrenergic, histamine, serotonin, and cannabinoid receptors; isolated organ studies

Special Issue Information

Dear Colleagues,

Today, many people suffer from chronic overload with nutrients, which together with decreased physical activity, often leads to a morbid increase in body fat mass. The prevalence of obesity is increasing, and it is an established risk factor for several comorbidities including diabetes, hypertension, chronic kidney disease, and fatty liver disease. The significant social and financial burden associated with obesity has warranted the search for therapeutic targets to reduce the accompanying pathophysiological changes. Decoding the underlying cellular and molecular mechanisms that control feeding behavior and metabolic changes may help to develop pharmacological interventions for obesity-related disorders.

Unfortunately, the world is rapidly changing and many factors still cause and will cause an increase in the incidence of some diseases more often than others. In recent years, obesity has become a major health issue worldwide. Even the current COVID-19 pandemic might very soon contribute to a significant increase in the incidence of obesity, as well as associated complications. Therefore, new and better therapeutic targets in the treatment of this condition, as well as specific small molecules that affect these targets, are much needed. Pharmaceuticals invites you to submit both reviews and original articles in the following fields: medical chemistry, experimental pharmacology, molecular biology, biochemistry, pharmacokinetics, and drug form technology. Appropriate subjects include novel molecular targets, intrinsic pathways involved in mechanisms of bodyweight reduction and compensation of accompanying metabolic disorders and physiological, biochemical, and pharmacological bases of drug action and its metabolism. The collection of manuscripts will be published as a Special Issue of the journal.

Dr. Magdalena Kotańska
Prof. Dr. Amélia Pilar Rauter
Dr. Małgorzata Szafarz
Dr. Monika Kubacka
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • obesity
  • metabolic disorders
  • new targets in obesity treatment
  • specific small molecules
  • new forms of anti-obesity drugs

Published Papers

This special issue is now open for submission.
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