Drug Discovery and Development for Tropical Diseases (TDs)

Dear Colleagues,

Tropical diseases (TDs) cause immense human suffering and death. They represent a huge socioeconomic and life-threatening burden in less-developed countries. In the last 20 years, a great effort has been made by the international scientific community to tackle this problem and discover new safe and effective drugs against TDs, including the most neglected tropical diseases (NTDs) (https://www.who.int/teams/control-of-neglected-tropical-diseases). In this this Special Issue, we would like to provide a picture of the recent discoveries in the field of drug discovery for TDs. We will acknowledge research papers which topic includes, but is not restricted to, the design, synthesis, in vitro/in vivo evaluation, and development of new compounds for TDs, including promising chemotherapeutic targets to combat these diseases. Review articles outlining recent developments in the field are also welcome.

This special issue covers (but is not restricted to) the Tropical Diseases listed below:

• Buruli ulcer
• Chagas disease (American trypanosomiasis) 
• Dengue      
• Dracunculiasis (Guinea-worm disease)    
• Echinococcosis   
• Foodborne trematode infections    
• Human African trypanosomiasis (sleeping sickness)
• Leishmaniasis·       
• Leprosy (Hansen's disease)
• Lymphatic filariasis (Elephantiasis)  
• Malaria
• Mycetoma, chromoblastomycosis, and other deep mycoses
• Onchocerciasis (river blindness)
• Rabies      
• Scabies and other ectoparasitoses  
• Schistosomiasis (Bilharzia)
• Soil-transmitted helminthiases
• Snakebite envenoming
• Taeniasis and cisticercosis
• Trachoma
• Yaws (Endemic treponematoses)

Dr. Christophe Dardonville
Collection Editor

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