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Immunogenomics for Drug Discovery in Leukemia
This special issue belongs to the section “Medicinal Chemistry“.
Special Issue Information
Dear Colleagues,
Leukemia is a group of hematological diseases that are highly heterogeneous in terms of their clinical, molecular and therapeutic response and remains an important cause of morbidity and mortality in children and adults. In fact, although leukemia treatment protocols have been improved during the last decade, the morbidity and mortality rates resulting from these diseases persist as an important public health problem in many populations. Since the Human Genome Project was launched, there have been notable advances in our understanding of the genomic basis of leukemia and the role of genetic mutations in relapse and chemoresistance. Therefore, more efforts are needed to discover new biomolecules for early diagnosis, the monitoring of residual disease, early detection of relapses, and the development of more suitable treatments for leukemia subtypes. This Special Issue aims to highlight current knowledge on the use of immunogenomics approaches to achieve personalized medicine to treat these diseases.
We encourage the submission of review papers and original manuscripts containing new and unpublished data related to omics studies and experimental models of leukemia with the aim of discovering new therapeutic approaches.
Dr. Silvia Jiménez-Morales
Dr. Adolfo Martínez-Tovar
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- leukemia
- hematological diseases
- immunogenomics
- omics studies
- experimental models
- therapeutic approaches
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