Advances in Circoviruses
This special issue belongs to the section "Viral Pathogens".
Special Issue Information
Dear Colleagues,
Circoviruses are a heterogeneous viral group infecting several animals hosts. Currently, research has largely focused on a limited number of avian and porcine circoviruses species, porcine circovirus 2 (PCV-2) in particular, because of their clinical and economic relevance. The improvements in diagnostic techniques and sequencing technologies have led to the discovery of a multitude of other viral species in different hosts. However, the knowledge of the distribution, epidemiology, infectious cycle, and potential pathogenesis of these newly discovered viruses is essentially lacking. Although the clinical relevance seems negligible in most cases, the multifactorial nature of these infections cannot be overemphasized: nowadays, devastating circovirus diseases mostly emerge when changes in farming conditions allow them to evolve from subclinical infections to posing a significant threat to animal health and productivity. Therefore, other circoviruses may represent a menace to companion animal and livestock welfare and/or wildlife conservation, thus requiring more extensive and dedicated studies.
Several aspects regarding infection dynamics, pathogenesis, and immunity also remain elusive for economically relevant and widely studied species like PCV-2 and the recently discovered PCV-3, demonstrating the complexity of these only apparently simple viruses.
For these reasons, this Special Issue welcomes any study providing a substantial advancement in circovirus knowledge, with a particular focus on, but not limited to, new species discovery, genomics, epidemiology and ecologic implications, biological cycle, virus–host interactions, pathogenesis, immunity, and disease control.
Prof. Michele Drigo
Dr. Giovanni Franzo
Guest Editors
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Keywords
- circoviruses
- epidemiology
- immunopathogenesis
- vaccination
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