Host–Pathogen Interactions in Intracellular Infections: From Immune Sensing to Vaccine Development
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Immunological Responses and Immune Defense Mechanisms".
Deadline for manuscript submissions: 31 March 2027 | Viewed by 103
Editor
Interests: innate immunity; inflammasomes; cytosolic sensors; STING; intracellular infections
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Innate immunity is the first arm of the immune system to be triggered in host defense against pathogens. Later, the adaptive immune response kicks in and plays a major role in protection against infection. However, further studies are required to elucidate this complex circuit by which the host immune system recognizes and destroy intracellular pathogens. Of particular interest is also how intracellular pathogens escape innate immune recognition. Innate immune activators are directly related to vaccine adjuvants, a research field that bridges the gap between basic science and translational research.
Therefore, we also welcome in this Special Issue vaccine manuscripts from pre-clinical to clinical trials with a great deal of innovation. Cutting-edge approaches such as nanoparticle-based vaccines, mRNA, integration of artificial intelligence (AI), issues related to immunogenicity, safety, regulatory aspects of vaccine production will also be discussed. For this Special Issue of Pathogens, we invite you to submit a review or research article related to host immune responses, innate immune sensing, inflammation, T and B cell responses, vaccine development, immune evasion, pathology and pathogenesis of bacterial, viral, fungal, or parasite infections.
We look forward to your contribution.
Prof. Dr. Sergio Costa Oliveira
Guest Editor
Manuscript Submission Information
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Keywords
- immune sensing
- vaccine development
- intracellular pathogens
- trained immunity
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