Special Issue "Diet, Gut Microbiota and Metabolic Disorders"

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: 20 March 2020.

Special Issue Editors

Prof. Ana Rivas
E-Mail Website
Guest Editor
Department of Nutrition and Food Science, University of Granada, Spain
Interests: human nutrition; hormones; food; microbiota; endocrine-related diseases
Dr. Margarita Aguilera
E-Mail Website
Guest Editor
Department of Microbiology, University of Granada, Spain
Interests: microbiota; obesity, food

Special Issue Information

Dear Colleagues,

Over the last decade, growing evidence has identified the gut microbiota and its disturbance as a potential factor in the pathophysiology of metabolic disorders, including obesity or diabetes. Diet effects on intestinal microbial composition and its role in pathogenetic mechanisms that are responsible for metabolic disorders represent, at the moment, one of thes most promising topics in nutrition research. However, it is necessary for them to be further explored in order to understand and interrupt the pathogenetic mechanisms, which support metabolic diseases.

Although not completely elucidated, the link between microbes and the onset of specific metabolic diseases such as obesity could lead to the development of therapeutic methods using nutrients or probiotics to prevent or cure these diseases.

Hence, the aim of the current Special Issue is to report evidence for a link of the gut microbiota with human metabolic disorders, to provide insights into this association, and to address the effect of diet on this relationship.

Prof. Ana Rivas
Dr. Margarita Aguilera
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Microbiota
  • Metabolic disorders
  • Diet
  • Nutrition
  • Obesity
  • Diabetes
  • Metabolic syndrome

Published Papers (1 paper)

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Research

Open AccessArticle
Rice Endosperm Protein Administration to Juvenile Mice Regulates Gut Microbiota and Suppresses the Development of High-Fat Diet-Induced Obesity and Related Disorders in Adulthood
Nutrients 2019, 11(12), 2919; https://doi.org/10.3390/nu11122919 - 02 Dec 2019
Abstract
Obesity and related disorders, which are increasing in adults worldwide, are closely linked to childhood diet and are associated with chronic inflammation. Rice endosperm protein (REP) intake during adulthood has been reported to improve lipid metabolism and suppress the progression of diabetic kidney [...] Read more.
Obesity and related disorders, which are increasing in adults worldwide, are closely linked to childhood diet and are associated with chronic inflammation. Rice endosperm protein (REP) intake during adulthood has been reported to improve lipid metabolism and suppress the progression of diabetic kidney disease in animal models. However, the effects of REP intake during childhood on adulthood health are unclear. Therefore, we used a mouse model to experimentally investigate the preconditioning effects of REP intake during childhood on the development of obesity and related disorders in adulthood. Male C57BL/6J mice were pair-fed a normal-fat diet containing casein or REP during the juvenile period and then a high-fat diet (HFD) containing casein or REP during adulthood. Mice fed REP during the juvenile period showed better body weight, blood pressure, serum lipid profiles, lipopolysaccharide (LPS)-binding protein levels, and glucose tolerance in adulthood than those fed casein during the juvenile period. HFD-induced renal tubulo-glomerular alterations and hepatic microvesicular steatosis were less evident in REP-fed mice than in casein-fed ones. REP intake during the juvenile period improved HFD-induced dysbiosis (i.e., Escherichia genus proliferation and reduced gut microbiota diversity), thereby suppressing endotoxin-related chronic inflammation. Indeed, REP-derived peptides showed antibacterial activity against Escherichia coli, a major producer of LPS. In conclusion, REP supplementation during the juvenile period may regulate the gut microbiota and thus suppress the development of obesity and related disorders in adulthood in mice. Full article
(This article belongs to the Special Issue Diet, Gut Microbiota and Metabolic Disorders)

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Name: Eric Houdeau
Affiliation: Neuro-Gastroenterology and Nutrition Unit, Unité Mixte de Recherche 1054, ToxAlim Research Center, Institut National de Recherche Agronomique, Toulouse 31027 cedex 3, France
Topic/Title: diet, gut dysbiosis, inmune system

Name: Mangesh Bhide
Affiliation: Department of Microbiology and inmunology. University of Veterinary medicine and pharmacy, Kosice, Slovakia
Topic/Title: microbiology, inmunology, diet

Name: Antonio Suarez
Affiliation: Department of Biochemistry, University of Granada
Topic/Title: microbiota, obesity, children

Name: Philippe Gerard
Affiliation: Microbiologie de l'Alimentation au Service de la Santé Humaine (MICALIS), French National Institute for Agricultural Research
Topic/Title: microbiota, metabolic diseases

Name: Konstantinos Gerasimidis
Affiliation: Department of Pediatric Gastroenterology, Hepatology and Nutrition, Royal Hospital of Sick Children, Glasgow, G3 8SJ, UK
Topic/Title: nutrition, chilldren, microbiota, inflamatory diseases

Name: Victor Gerdes
Affiliation: Wallenberg Laboratory, University of Gothenberg, Gothenberg, Sweden
Topic/Title: Microbiota, diabetes, nutrition

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