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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Metal Ions and Metal Complexes in Medicinal Chemistry submission deadline 28 Feb 2026 | Viewed by 28 | Submission Open
Keywords: metal ions; metal complexes; synthesis; study; spectral analysis; biological activity; ligands
(This special issue belongs to the Section Medicinal Chemistry)
Advanced Electrocatalysts: Design, Characterization, and Applications in Sustainable Conversion Reactions
edited by Bruno Manzolli Rodrigues
submission deadline 28 Feb 2026 | Viewed by 26 | Submission Open
Keywords: electrocatalysis; nanostructured catalysts; atomically dispersed catalysis; sustainable catalysis; oxygen reduction reaction (ORR); oxygen evolution reaction (OER); CO2 reduction reaction (CO2RR); biomass conversion
(This special issue belongs to the Section Electrochemistry)
Recent Advances in Functionalized Nanomaterials: Design, Synthesis, Characterization, and Application—2nd Edition
edited by
submission deadline 28 Feb 2026 | Viewed by 26 | Submission Open
Keywords: functionalized nanomaterials; functionalized strategies; compositions; nanostructures; energy storage; sensing; environmental remediation; catalytic
(This special issue belongs to the Section Nanochemistry)
Advanced Photocatalysts for Environmental Remediation and Contaminant Removal
edited by
submission deadline 28 Feb 2026 | Viewed by 25 | Submission Open
Keywords: nonbiodegradable organic contaminants; antibiotic contaminants; dye contaminants; pesticide pollutants; photocatalytic degradation; advanced photocatalysts; oxidic radicals; degradation pathways; degradation mechanism; photophysical property; photochemical property
(This special issue belongs to the Section Applied Chemistry)
Biodegradable Polymers in Biological Application submission deadline 28 Feb 2026 | Viewed by 25 | Submission Open
Keywords: natural polymers; synthetic polymers; controlled degradation; compositional and structural modifications; processing
(This special issue belongs to the Section Macromolecular Chemistry)
Advancements on Field Detection Based on Nucleic Acid Amplification
edited by Xiong Xiong, and
submission deadline 28 Feb 2026 | Viewed by 25 | Submission Open
Keywords: nucleic acid; isothermal amplification; visual detection; colorimetric detection; fluorescence-based detection; point-of-care test; field detection
(This special issue belongs to the Section Analytical Chemistry)
Organometallic Compounds: Synthesis and Catalysis submission deadline 28 Feb 2026 | Viewed by 23 | Submission Open
Keywords: organometallic compounds; synthesis; catalysis; chemistry; structure
(This special issue belongs to the Section Organometallic Chemistry)
Nitrogen Containing Heterocyclic Scaffolds: Synthesis and Bioactivity
edited by and
submission deadline 28 Feb 2026 | Viewed by 21 | Submission Open
Keywords: heterocycles; heteroaromatics; drug discovery; organic synthesis; structure-activity relationship
(This special issue belongs to the Section Medicinal Chemistry)
Metal-Organic Framework-Derived Materials for High-Performance Ion Batteries
edited by and Wenting Li
submission deadline 28 Feb 2026 | Viewed by 20 | Submission Open
Keywords: metal– organic frameworks; MOF-derived materials; high-performance ion batteries; electrochemical performance; energy conversion; energy storage; nanoporous materials
(This special issue belongs to the Section Materials Chemistry)
Advances in Chemical Analysis Procedures (Part III): Future Trends in Reducing the Environmental Impact submission deadline 28 Feb 2026 | Viewed by 19 | Submission Open
Keywords: green approaches; analytical chemistry; instrumental analysis; sample preparation; quantitative analysis; AI; tools; metrics
(This special issue belongs to the Section Analytical Chemistry)
Theme Issue in Honor to Prof. Dr. Douglas Stephan’ Great Achievement in Inorganic Chemistry
edited by Meera Mehta and Andrew Jupp
submission deadline 28 Feb 2026 | Viewed by 17 | Submission Open
Keywords: inorganic chemistry; catalysis; complexes
Research on Changes in Nutritional Components and Structure During Food Processing
edited by , Wei Qin and Natthawuddhi Donlao
submission deadline 28 Feb 2026 | Viewed by 17 | Submission Open
Keywords: food structure; nutritional components; bioactive compounds; food processing; phytochemicals; health benefits
(This special issue belongs to the Section Food Chemistry)
Emerging Trends in Two-Dimensional Materials: Synthesis, Properties and Applications
edited by Xiao Zhi
submission deadline 28 Feb 2026 | Viewed by 14 | Submission Open
Keywords: two-dimensional materials; biosensors; graphene; energy storage; catalysis; electronic conductivity
(This special issue belongs to the Section Materials Chemistry)
Recent Advances in Green and Enzymatic Catalysis for Synthesis of Functional Molecules
edited by
submission deadline 28 Feb 2026 | Viewed by 13 | Submission Open
Keywords: green catalysis; enzymatic synthesis; sustainable chemistry; biocatalysis; functional molecules
(This special issue belongs to the Section Bioorganic Chemistry)
Theoretical, Computational and Experimental Advances on Molecular Optical Properties, 2nd Edition submission deadline 28 Feb 2026 | Viewed by 10 | Submission Open
Keywords: synthesis; theoretical computation; photophysical characterization; structure– propertyies relationship; bio-application; imaging
(This special issue belongs to the Section Physical Chemistry)
Fluorescent Sensing in Food and Environmental Detection submission deadline 28 Feb 2026 | Viewed by 8 | Submission Open
Keywords: environmental pollutants; food contaminants; organic residues; heavy metals; fluorescent sensing; fluorescent materials; food analysis; food quality; pollutant monitoring; food safety
(This special issue belongs to the Section Analytical Chemistry)
Advances in Radiation Detection Materials and Technology
edited by Qianli Li
submission deadline 28 Feb 2026 | Viewed by 8 | Submission Open
Keywords: radiation-sensitive material; scintillation material; luminescent center optimization; radiation detection materials; flexible dosimeter; semiconductor heterostructure engineering; synthesis; characterization; application; determination of the crystal structure of biomacromolecules
Plant Bioactive Compounds in Pharmaceuticals, 2nd Edition submission deadline 28 Feb 2026 | Viewed by 3 | Submission Open
Keywords: bioactive compounds; medicinal plant; phytocomplexes; cell cultures
(This special issue belongs to the Section Natural Products Chemistry)
Gemini Surfactant Application Studies
edited by Iwona Kowalczyk and
submission deadline 1 Mar 2026 | Viewed by 67 | Submission Open
Keywords: gemini surfactants; biological activity; physicochemical analysis; smart material
(This special issue belongs to the Section Applied Chemistry)
Magnetic Resonance in Food Analysis, 2nd Edition submission deadline 15 Mar 2026 | Viewed by 223 | Submission Open
Keywords: NMR spectroscopy; relaxometry; pulse sequences; molecular interactions; diffusion; imaging; foods
(This special issue belongs to the Section Food Chemistry)
Exploring the Antioxidant Activity of Natural Extracts: New Findings and Potential Food- and Non-Food-Related Applications
edited by
submission deadline 26 Mar 2026 | Viewed by 482 | Submission Open
Keywords: natural antioxidants; superfruits; specialty crops; polyphenols; flavonoids; tannins; anthocyanins; carotenoids; vitamins; phytochemistry; extraction techniques; processing; functional food; sustainable technology; technical applications; antifouling; obesity; inflammation; diabetes; cosmetics; pharmaceuticals; environmental protection; material science; radical scavenging; nutraceuticals
(This special issue belongs to the Section Natural Products Chemistry)
Plant and Animal Bioreactors: Insights into Bioactive Molecules for Therapeutic Innovation submission deadline 30 Mar 2026 | 1 articles | Viewed by 694 | Submission Open
Keywords: plant bioreactors; animal bioreactors; bioproduction; plant metabolites; plant hormones; biologics; biosimilars; drug research and development; nutraceuticals; plant engineering; pharmaceutical biotechnology; agricultural biotechnology; bioactive molecules
(This special issue belongs to the Section Natural Products Chemistry)
Stress-Related Biomarkers: Analytical Methods and Their Applications
edited by
submission deadline 30 Mar 2026 | Viewed by 278 | Submission Open
Keywords: biomarkers; stress hormones; advanced glycation end-products; mental and physical stress; oxidative stress; glycation stress; Immunological stress; fatigue; aging; lifestyle-related diseases
(This special issue belongs to the Section Analytical Chemistry)
Flavor Scalping submission deadline 30 Mar 2026 | Viewed by 29 | Submission Open
Keywords: flavor compound absorption; plastic packaging materials; polyolefins; polyethyene terephthalate; product flavor loss; product sensory quality
(This special issue belongs to the Section Flavours and Fragrances)
Novel Edible Proteins: Strategies for Improving Nutrient Bioavailability
edited by Yaqin Wang and Ndegwa Henry Maina
submission deadline 30 Mar 2026 | Viewed by 15 | Submission Open
Keywords: proteins; nutrient; bioavailability; protein modification; fermentation; chemistry; digestion; digestibility; anti-nutritional factors; health
(This special issue belongs to the Section Food Chemistry)
π-Conjugated Functional Molecules & Polymers submission deadline 31 Mar 2026 | 15 articles | Viewed by 27544 | Submission Open
Keywords: π -conjugated functional materials; conjugated porous polymers; covalent organic framework; metal– organic framework; synthetic methodology; aggregation-induced organic emissions; nonlinear optics; light-emitting diodes; organic field effect transistors; organic photovoltaic cells; photocatalysis
(This special issue belongs to the Section Materials Chemistry)
Bioactive Compounds: Applications and Benefits for Human Health
edited by Sara Baldelli, and
submission deadline 31 Mar 2026 | 4 articles | Viewed by 7006 | Submission Open
Keywords: bioactive compounds; polyphenols; terpenoids; alkaloids; glucosinolates; antioxidant; anti-inflammatory; cardiovascular diseases; bacterial and viral infections; microbiota; neurodegenerative diseases; cancer; sarcopenia; identification; purification; extraction; pre-clinical; clinical
(This special issue belongs to the Section Natural Products Chemistry)
Design, Synthesis and Applications of Novel Transition Metal Catalysts
edited by Hui Jiang and Junfang Gong
submission deadline 31 Mar 2026 | 5 articles | Viewed by 6073 | Submission Open
Keywords: pincer catalysts; transition metal catalysts; organic synthetic methodologies; photocatalysis; electrocatalysis; polymerization; fine chemistry
(This special issue belongs to the Section Applied Chemistry)
Hypervalent Iodine Chemistry: Promise and Prospects
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 5314 | Submission Open
Keywords: hypervalent compound; iodine; new reagent and catalyst; new synthetic transformation; synthetic application; the hypervalent iodine-bearing hybrid molecule
(This special issue belongs to the Section Organic Chemistry)
Research Progress on Functional Lipids and Their Applications in Health Food Systems
edited by
submission deadline 31 Mar 2026 | 5 articles | Viewed by 4165 | Submission Open
Keywords: lipid crystallization; lipid oxidation; enzymatic lipid modification; processing; health benefits; structured emulsions; lipid emulsions; lipids capsules
(This special issue belongs to the Section Food Chemistry)
Advances in Functional Polymers and Their Applications
edited by and
submission deadline 31 Mar 2026 | 5 articles | Viewed by 3675 | Submission Open
Keywords: functional polymer; polymerization; post-polymerization modification; multi-component; hydrogel; 3D printing; biomaterials; polymer composite; surface and interface
(This special issue belongs to the Section Macromolecular Chemistry)
Organic Molecules in Drug Discovery and Development
edited by
submission deadline 31 Mar 2026 | 3 articles | Viewed by 2849 | Submission Open
Keywords: organic chemistry; chemical synthesis; chemical modifications; organic molecules; molecular mechanisms; bioactivity; drug development; drugs
(This special issue belongs to the Section Medicinal Chemistry)
Review Papers in Analytical Chemistry, 2nd Edition
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2101 | Submission Open
Keywords: analytical chemistry; analytical spectroscopy; environmental sciences; medical science; forensic science; cultural heritage; food analysis
(This special issue belongs to the Section Analytical Chemistry)
In Silico Methods Applied in Drug and Pesticide Discovery, 3rd Edition submission deadline 31 Mar 2026 | 3 articles | Viewed by 1599 | Submission Open
Keywords: molecular modeling of small and complex molecules/macromolecules; homology modeling; molecular docking; virtual screening; ADME-Tox; ligand- and structure-based pharmacophore modeling; QSAR/QSPR models; drug/pesticide design; molecular dynamics
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Porous Carbons for CO2 Adsorption and Capture
edited by and Jinsong Shi
submission deadline 31 Mar 2026 | 2 articles | Viewed by 1415 | Submission Open
Keywords: porous carbons; carbon nanotubes; graphene oxide; carbon nanomaterials; activated carbons; adsorbents; CO2 adsorption; CO2 capture; physisorption; chemical activation; physical activation; surface functionalization; pore structure design; carbon doping; nitrogen doping; CO2 capture efficiency; CO2 selectivity; direct air capture (DAC); CO2 storage; industrial CO2 capture; carbon capture and utilization (CCU); CO2 adsorption mechanisms; adsorption kinetics; sustainable materials; adsorbent regeneration; machine learning in material design
(This special issue belongs to the Section Materials Chemistry)
Exclusive Papers of Editorial Board Members and Invited Scholars in “Materials Chemistry”, 2nd Edition
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 1333 | Submission Open
Keywords: biomaterials; nanomaterials; hybrid materials; core-shell materials; thin films; self-assembling systems; hydrogels; sensors and biosensors
(This special issue belongs to the Section Materials Chemistry)
Recent Advances in the Toxicology and Safety of Medicinal Plants and Natural Products submission deadline 31 Mar 2026 | 2 articles | Viewed by 1287 | Submission Open
Keywords: toxicity of natural compounds and plant extracts; safety of natural products; drug development; in silico modeling; in vitro study; in vivo study
(This special issue belongs to the Section Natural Products Chemistry)
Biologically Active Compounds in Functional Foods submission deadline 31 Mar 2026 | 1 articles | Viewed by 474 | Submission Open
Keywords: functional foods; bioactive compounds; vitamins; antioxidants; phenolics; functional ingredients; functional properties; fortified foods; enriched foods; food chemistry; bioavailability; food matrix
(This special issue belongs to the Section Food Chemistry)
Polymeric Nano-Based Drug Delivery Systems submission deadline 31 Mar 2026 | Viewed by 243 | Submission Open
Keywords: nanotechnology; polymers; biopolymers; drug delivery; encapsulation; essential oils; blood-brain barrier
(This special issue belongs to the Section Macromolecular Chemistry)
Functional Biomaterials—Structure, Function, and Applications
edited by
submission deadline 31 Mar 2026 | Viewed by 165 | Submission Open
Keywords: biomaterials; tissue regeneration; drug delivery; hierarchical scaffolds; dynamic hydrogels; hybrid nanocomposites; bioactive components; targeted therapeutics; personalized medicine; biomedical engineering
Advances in Conversion of Biomass
edited by and Anjani Ravi Kiran Gollakota
submission deadline 31 Mar 2026 | Viewed by 146 | Submission Open
Keywords: biomass conversion; bio-based material; catalyst design; heterogeneous catalysis; enzyme catalysis
(This special issue belongs to the Section Green Chemistry)
Nanocellulose-Based Materials: Production and Applications
edited by and
submission deadline 31 Mar 2026 | Viewed by 119 | Submission Open
Keywords: nanocellulose; preparation; mechanical methods; chemical methods; biological methods; application; medical and biotechnology; composite materials; food industry; optical devices; sensors
(This special issue belongs to the Section Materials Chemistry)
Recent Progress in Environmental Analytical Chemistry submission deadline 31 Mar 2026 | Viewed by 80 | Submission Open
Keywords: environmental monitoring; water; air and soil pollution; pollution analysis; environmental toxicity; analytical chemistry; chemometrics; method development for analysis of environmental compartments; method validation
(This special issue belongs to the Section Analytical Chemistry)
A Themed Issue in Honor of Professor Hans-Joachim Knölker: Creator of the Knölker Complex
edited by
submission deadline 31 Mar 2026 | Viewed by 76 | Submission Open
Keywords: hydrogenation; dehydrogenation; oxidation; reduction; alkylation; coupling reaction; organometallic synthesis; bifunctional complex
(This special issue belongs to the Section Organometallic Chemistry)
Feature Papers in Organic Chemistry—Third Edition
edited by and
submission deadline 31 Mar 2026 | Viewed by 73 | Submission Open
Keywords: organic synthesis; organic chemistry research; synthesis methods; theoretical study; reaction mechanisms; catalysis
(This special issue belongs to the Section Organic Chemistry)
Photo- and Sonodynamic Antimicrobial Compounds submission deadline 31 Mar 2026 | Viewed by 71 | Submission Open
Keywords: photosensitizers; sonosensitizers; photodynamic treatment; sonodynamic treatment; antimicrobials
(This special issue belongs to the Section Medicinal Chemistry)
Synthesis and Application of Disulfide Compounds submission deadline 31 Mar 2026 | Viewed by 71 | Submission Open
Keywords: organic chemistry; poly(disulfide)s; dithioglycosides; cyclization of peptides; drug discovery; chemical biology; prodrug development; dynamic and recyclable material
(This special issue belongs to the Section Medicinal Chemistry)
Current Emerging Trends of Extraction and Encapsulation in Food, 2nd Edition submission deadline 31 Mar 2026 | Viewed by 66 | Submission Open
Keywords: extraction; encapsulation; drying; emulsion; targeted delivery; stability; bioactive compounds; nonthermal technologies; bioavailability; functional foods
(This special issue belongs to the Section Food Chemistry)
Discovery and Development of Anti-Cancer Drugs: From Signalling Pathways to Molecular Mechanisms
edited by and Lívia Bitencourt Pascoal
submission deadline 31 Mar 2026 | Viewed by 56 | Submission Open
Keywords: discovery of small-molecule inhibitors targeting oncogenic kinases and transcription factors; mechanisms of action and resistance for current and emerging cancer drugs; targeting DNA damage response pathways (e.g.; PARP; ATR; ATM inhibitors); molecular crosstalk between tumor cells and the immune system; role of epigenetics in cancer drug resistance and sensitivity; tumor metabolism as a therapeutic target in Immunochemistry; structure-based drug design and virtual screening; antibody– drug conjugates and novel biologic therapeutics; RNA-targeting therapeutics and mRNA-based cancer vaccines; advances in PROTACs and targeted protein degradation; application of AI and computational chemical biology in drug discovery
(This special issue belongs to the Section Chemical Biology)
Bioactive Compounds in Plants: Extraction and Application submission deadline 31 Mar 2026 | Viewed by 56 | Submission Open
Keywords: bioactive compounds; extraction; biological activities
(This special issue belongs to the Section Natural Products Chemistry)
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