C-H Bond Functionalization of Heterocyclic Compounds
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 79
Special Issue Editor
Special Issue Information
Dear Colleagues,
The functionalization of C-H bonds in heterocyclic compounds represents a transformative strategy in modern organic synthesis, enabling the direct modification of complex molecular frameworks with high efficiency and selectivity. This Special Issue focuses on recent advancements in methodologies, catalysts, and mechanistic insights regarding the activation of C-H bonds in heterocycles, which are pivotal structures in natural products, pharmaceuticals, agrochemicals, and materials science. We welcome submissions that highlight innovative approaches, such as transition metal catalysis, photoredox chemistry, and electrochemical methods, as well as the development of sustainable and atom-economical protocols. This Special Issue also explores the challenges and opportunities associated with achieving site-selective functionalization, stereocontrol, and the application of these techniques to the synthesis of biologically active molecules. By showcasing innovative research, this collection aims to inspire further exploration and collaboration in this dynamic field, driving the development of greener and more efficient synthetic routes for heterocyclic compounds.
Prof. Dr. Dong Wang
Guest Editor
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Keywords
- heterocycles
- C-H activation
- transition metal catalysis
- site-selectivity
- sustainable synthesis
- photoredox chemistry
- electrochemical functionalization
- biologically active molecules
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