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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Review Papers in Inorganic Chemistry
edited by
submission deadline 30 Sep 2026 | Viewed by 237 | Submission Open
Keywords: coordinative compounds; metallodrug; biological activity; target biomolecule; essential ion; carrier
(This special issue belongs to the Section Inorganic Chemistry)
Design and Application of Multifunctional Sensing Materials
edited by and Aiwu Wang
submission deadline 30 Sep 2026 | Viewed by 236 | Submission Open
Keywords: multifunctional sensing materials; chemical sensors; electrochemical biosensors; optical sensing; nanomaterials; graphene-based materials; semiconductor sensors; wearable sensing; biomedical diagnostics; environmental monitoring
(This special issue belongs to the Section Materials Chemistry)
Innovations in the Use of Peptides and Proteins for Medical Applications submission deadline 30 Sep 2026 | Viewed by 236 | Submission Open
Keywords: therapeutic peptide–proteins; peptide synthesis; biophysical study of proteins and peptides; clinical applications; theranostics; drug discovery; drug delivery; nanotechnology
(This special issue belongs to the Section Medicinal Chemistry)
Recent Progress in the Synthesis and Applications of Photocatalysts: Environmental and Energy Applications
edited by Alexandra Ioannidi, and
submission deadline 30 Sep 2026 | Viewed by 232 | Submission Open
Keywords: photocatalysts; photocatalytic technologies; water and wastewater treatment; degradation of emerging contaminants; hydrogen production; CO₂ reduction; solar-to-chemical energy conversion
(This special issue belongs to the Section Photochemistry)
Catalysis for Biomass Transformation
edited by
submission deadline 30 Sep 2026 | Viewed by 232 | Submission Open
Keywords: biomass conversion, catalysis; bio-based fuels, renewable feedstocks; sustainable chemical processes, biorefineries
(This special issue belongs to the Section Green Chemistry)
Exosomes in Tumor Therapy: Molecular Mechanisms and Therapeutic Applications
edited by
submission deadline 30 Sep 2026 | Viewed by 231 | Submission Open
Keywords: exosomes; tumor therapy; drug delivery; immune modulation; molecular mechanisms; biomarkers
(This special issue belongs to the Section Chemical Biology)
Advancements and Applications of Organocatalysis in Sustainable Chemistry
edited by
submission deadline 30 Sep 2026 | Viewed by 221 | Submission Open
Keywords: organocatalysis; synergistic organocatalysis; green synthesis; pharmaceutical and fine chemical synthesis; polymer synthesis; biomass and feedstock valorization; process intensification
(This special issue belongs to the Section Organic Chemistry)
Synergistic Effect in Nanomaterials for Electrocatalytic Hydrogen and Oxygen Conversion
edited by
submission deadline 30 Sep 2026 | Viewed by 221 | Submission Open
Keywords: electrocatalysis; fuel cell catalysts; electrochemical carbon dioxide reduction; hydrogen evolution reaction; oxygen evolution reaction; water splitting
(This special issue belongs to the Section Electrochemistry)
Potential of Natural Extracts for Cosmetics submission deadline 30 Sep 2026 | Viewed by 217 | Submission Open
Keywords: natural extracts; cosmetic applications; delivery system; pharmacological activity; bioactive compounds; therapeutic potential; medicinal plants; drug discovery; phytochemistry
(This special issue belongs to the Section Medicinal Chemistry)
A Closer Look into Advanced Oxidation Processes for Water Remediation
edited by
submission deadline 30 Sep 2026 | Viewed by 215 | Submission Open
Keywords: advanced oxidation processes; water remediation; photocatalysis; hydroxyl radicals; emerging contaminants; pharmaceutical pollutants; fenton and photo-Fenton; ozonation; persulfate activation; electrochemical oxidation; catalyst development; reaction kinetics; degradation mechanisms; toxicity assessment; hybrid treatment systems; sustainable water treatment
(This special issue belongs to the Section Green Chemistry)
Photochemical Attenuation of Contaminants
edited by
submission deadline 30 Sep 2026 | Viewed by 209 | Submission Open
Keywords: contaminants of emerging concern; light-induced processes; photochemical decontamination; water photochemistry; atmospheric photochemistry; photosensitized reactions
(This special issue belongs to the Section Photochemistry)
The Chemistry of Honey and Other Bee Products: Novel Applications and Quality, 2nd Edition
edited by
submission deadline 30 Sep 2026 | Viewed by 202 | Submission Open
Keywords: bee products; food; cosmetic and pharmaceutical applications; beehive as a source of functional ingredients; health-promoting food; quality criteria and standards; botanical and geographical origin; target compounds for quality assessment; phenolic compounds
(This special issue belongs to the Section Natural Products Chemistry)
Physicochemical and Bioactive Properties of Foods: Structure, Function, and Technological Potential submission deadline 30 Sep 2026 | Viewed by 201 | Submission Open
Keywords: physicochemical properties; bioactive compounds; food structure; characterization methods; processing technologies; encapsulation; bioavailability; food rheology
(This special issue belongs to the Section Food Chemistry)
Advances and Challenges in Luminescent Nanomaterials: From Synthesis to Applications submission deadline 30 Sep 2026 | Viewed by 198 | Submission Open
Keywords: spectroscopy of luminescent materials; fundamental properties of luminescent materials; luminescence mechanisms; characterization of luminescent materials; luminescence thermometry; bio-sensors
(This special issue belongs to the Section Nanochemistry)
New Insights in Pharmaceutical Analytical Chemistry
edited by
submission deadline 30 Sep 2026 | Viewed by 194 | Submission Open
Keywords: entire drug life cycle; separation techniques; spectrometric techniques; sensors; multidisciplinary tools; emerging trends
(This special issue belongs to the Section Analytical Chemistry)
Biomedical Applications of Natural and Synthetic Antioxidants submission deadline 30 Sep 2026 | Viewed by 189 | Submission Open
Keywords: oxidative stress; natural antioxidants; synthetic antioxidant molecules; antioxidant application
(This special issue belongs to the Section Medicinal Chemistry)
Lignin–Chemistry & Materials: An Update
edited by , Luca Zoia and Federica Ferruti
submission deadline 30 Sep 2026 | Viewed by 187 | Submission Open
Keywords: biorefinery; lignin; structural characterisation; fractionation; aromatics; nanomaterials; performance (co-)polymers
(This special issue belongs to the Section Green Chemistry)
Green and Bio-Based Materials for Environmental Remediation, Protection, and Sustainable Technologies: Feature Reviews submission deadline 30 Sep 2026 | Viewed by 186 | Submission Open
Keywords: green materials; bio-based materials; environmental remediation; sustainable materials; green corrosion inhibitors; biomass-derived compounds; eco-friendly coatings
(This special issue belongs to the Section Applied Chemistry)
Valorization of Biomass and Bioplastics for Recovery of Value-Added Products
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 169 | Submission Open
Keywords: valorization; biological; biodegradable; polymer; agricultural; residue; food; waste; lignocellulosic; biomass; bioplastic; electrochemical; catalytic; hybrid; biorefined; microbial; enzymatic; conversion; depolymerization; separation
(This special issue belongs to the Section Green Chemistry)
Biomedical Applications of Hydrogels: Current Status and Advances
edited by Miriam Di Martino and
submission deadline 30 Sep 2026 | Viewed by 157 | Submission Open
Keywords: hydrogels; injectable hydrogels; stimuli-responsive hydrogels; drug delivery; gene delivery; wound healing; tissue engineering; regenerative medicine; 3D bioprinting; biosensing
(This special issue belongs to the Section Macromolecular Chemistry)
QSAR and QSPR: Recent Developments and Applications, 5th Edition
edited by
submission deadline 1 Oct 2026 | 1 articles | Viewed by 812 | Submission Open
Keywords: QSAR/QSPR modelling; development of molecular descriptors; molecular structure representation; data mining; machine learning; regression QSAR/QSPR modelling; classification QSAR/QSPR modelling; model optimization protocols; model validation algorithms; model quality metrics; random accuracy; ensemble QSAR/QSPR modelling; applicability domain; QSAR/QSPR model interpretation; comparative modelling; drug design; drug discovery; environmentally-relevant activity; biological activity; physicochemical property
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Lignocellulosic Biomass Utilization: From Waste to Value-Added Products submission deadline 1 Oct 2026 | Viewed by 377 | Submission Open
Keywords: lignocellulosic biomass; value-added products; biomaterials; biorefinery; circular economy; bioenergy; sustainable development goals; green chemistry
(This special issue belongs to the Section Green Chemistry)
Biomarker for Molecular-Targeted Cancer Therapy
edited by
submission deadline 10 Oct 2026 | 2 articles | Viewed by 1739 | Submission Open
Keywords: biomarkers; chemical biology; targeted cancer therapy; molecular mechanisms; small-molecule probes; druggable pathways; precision oncology
(This special issue belongs to the Section Chemical Biology)
Biologically Active Compounds in Functional Foods submission deadline 15 Oct 2026 | 2 articles | Viewed by 3790 | Submission Open
Keywords: functional foods; bioactive compounds; vitamins; antioxidants; phenolics; functional ingredients; functional properties; fortified foods; enriched foods; food chemistry; bioavailability; food matrix
(This special issue belongs to the Section Food Chemistry)
Bioactive Compounds from Fruits and Vegetables submission deadline 15 Oct 2026 | 3 articles | Viewed by 1633 | Submission Open
Keywords: fruit and veggie products; bioactive compounds; food supplements and formulations; natural compounds; in vitro and in vivo bioavailability; antioxidant efficacy; green extraction and purification
(This special issue belongs to the Section Food Chemistry)
Computationally Guided Medicinal Chemistry: Molecular Modeling, Scaffold Design, and Multi-Target Drug Discovery submission deadline 15 Oct 2026 | 2 articles | Viewed by 1127 | Submission Open
Keywords: rational drug design; multi-target drug discovery; drug repurposing; scaffold design; computer-aided drug design (CADD); molecular modeling; predictive modeling
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Ultrasounds and Microwave Assisted Reactions as Modern Eco-Friendly Useful Tools in Medicinal Chemistry
edited by
submission deadline 15 Oct 2026 | Viewed by 285 | Submission Open
Keywords: microwave; microwave and ultrasounds; synthesis; cycloadditions; heterocycles; anticancer; antituberculosis; antimicrobials; anti-HIV; other biological activities; fluorescent derivatives for medicinal chemistry
(This special issue belongs to the Section Medicinal Chemistry)
Microfluidics: Applications for Analytical Purposes in Chemistry
edited by and
submission deadline 15 Oct 2026 | Viewed by 273 | Submission Open
Keywords: microfluidics; chemical analysis; lab-on-a-chip; biosensing
(This special issue belongs to the Section Analytical Chemistry)
Advances in Valorization Strategies for Grape By-Products
edited by and Yavor Lukanov Ivanov
submission deadline 15 Oct 2026 | Viewed by 223 | Submission Open
Keywords: grape by-products; valuable biologically active substances; biological activity; antioxidant, anti-inflammatory, antimicrobial and anticancer; green extraction; storage conditions; plant extracts, providing synergistic action; stabilization of purified extracts; cosmetics, food industry, medicine; biodegradable packaging films
(This special issue belongs to the Section Food Chemistry)
Phenolic Compounds from Plants submission deadline 16 Oct 2026 | Viewed by 328 | Submission Open
Keywords: phenolic compounds; analytical methods; chemical structure; biological activities; bioavailability
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Organic Synthesis in Pharmaceuticals, Agrochemicals and Materials—2nd Edition
edited by Zhao-Yang Wang and Le Li
submission deadline 30 Oct 2026 | 2 articles | Viewed by 1586 | Submission Open
Keywords: organic synthetic methods; synthesize pharmaceuticals, agrochemicals, and materials; organic photosynthesis; organic electrochemical synthesis; biocatalysis; AI-based organic synthesis
(This special issue belongs to the Section Organic Chemistry)
Radiochemistry: Present Status and Future Perspectives
edited by Gregory P. Holmbeck and
submission deadline 30 Oct 2026 | 1 articles | Viewed by 1272 | Submission Open
Keywords: actinides; isotope production; nuclear energy; nuclear medicine; radioisotopes; radiolysis; separations; waste management
(This special issue belongs to the Section Medicinal Chemistry)
Bioactive Compounds from Natural Sources: Novel Extraction Methods, Protection and Therapeutic Potential
edited by , and Liliana Alamilla
submission deadline 30 Oct 2026 | 1 articles | Viewed by 793 | Submission Open
Keywords: bioactive compounds; natural products; green extraction; purification; separation techniques; encapsulation; nanoencapsulation; therapeutic potential; drug discovery; nutraceuticals; stability; bioavailability
(This special issue belongs to the Section Natural Products Chemistry)
Emerging Contaminants in Environmental and Biological Systems: Analytical Challenges and Solutions submission deadline 30 Oct 2026 | Viewed by 300 | Submission Open
Keywords: emerging contaminants; trace analysis; new analytical methods and techniques; food; environmental matrices; sample preparation
(This special issue belongs to the Section Analytical Chemistry)
Thermodynamics of Metal Cation Coordination: From Fundamental Equilibria to Biological and Environmental Systems
edited by Clemente Bretti and Rosita Cappai
submission deadline 30 Oct 2026 | Viewed by 280 | Submission Open
Keywords: chemical speciation; metal cations; thermodynamic; stability constants; complexes; solution equilibria
Synthesis and Chemoenzymatic Approaches to Pharmaceutically Relevant Products and Intermediates
edited by , Raffaella Gandolfi and
submission deadline 30 Oct 2026 | Viewed by 259 | Submission Open
Keywords: organic synthesis; chemoenzymatic synthesis; active pharmaceutical ingredients (APIs); pharmaceutical intermediates; drug development; organometallic catalysis; stereo-controlled reactions
(This special issue belongs to the Section Organic Chemistry)
Drug Metabolism in Personalized Oncology: From Molecular Mechanisms to Clinical Translation
edited by
submission deadline 30 Oct 2026 | Viewed by 225 | Submission Open
Keywords: drug metabolism; anticancer drugs; polymorphisms; enzymes; drug biotransformation
(This special issue belongs to the Section Medicinal Chemistry)
Research on Chemical Composition and Activity of Natural Products, 2nd Edition submission deadline 31 Oct 2026 | 17 articles | Viewed by 19042 | Submission Open
Keywords: natural bioactive compounds; isolation and analysis; metabolism; in vitro and in vivo experiments; pharmacological study
(This special issue belongs to the Section Natural Products Chemistry)
5th Anniversary of Section "Flavours and Fragrances" and 30th Anniversary of Molecules
edited by
submission deadline 31 Oct 2026 | 8 articles | Viewed by 18792 | Submission Open
Keywords: flavor; aroma; taste; fragrances; volatilomics; flavoromics; sensomics; food flavors; analysis of flavor compounds
(This special issue belongs to the Section Flavours and Fragrances)
Anti-Aging and Skin Rejuvenation Ingredients: Design and Research
edited by , and Daniela Lucia Muntean
submission deadline 31 Oct 2026 | 7 articles | Viewed by 11193 | Submission Open
Keywords: anti-aging ingredients; skin rejuvenation; nutricosmetics and cosmeceuticals; bioactive compounds; formulation and delivery systems; extracellular matrix and skin biology; in silico, in vitro and in vivo assessment
(This special issue belongs to the Section Applied Chemistry)
Design, Synthesis and Biological Evaluation of Medicinal Potential Compounds—2nd Edition submission deadline 31 Oct 2026 | 8 articles | Viewed by 8599 | Submission Open
Keywords: bioactive compounds; design; synthesis; biological evaluation; in silico evaluation; in vitro evaluation; in vivo evaluation
(This special issue belongs to the Section Medicinal Chemistry)
Green Chemistry and Molecular Tools in Agriculture submission deadline 31 Oct 2026 | 7 articles | Viewed by 8431 | Submission Open
Keywords: sustainable agriculture; green chemistry; agri-food by-products; bioactive compounds; biostimulants; circular economy; molecular tools; eco-friendly agrochemicals; soil health; precision agriculture
(This special issue belongs to the Section Green Chemistry)
Synthesis and Derivatization of Heterocyclic Compounds
edited by Philipp Natho and
submission deadline 31 Oct 2026 | 7 articles | Viewed by 7720 | Submission Open
Keywords: heterocyclic compounds; spirocyclic compounds; enabling technology; synthetic methodologies; strained heterocycles; medicinal chemistry; fused compounds
(This special issue belongs to the Section Organic Chemistry)
Functional Foods: Bioactive Compounds, Antioxidants and Anti-Inflammatory Activities, 2nd Edition submission deadline 31 Oct 2026 | 10 articles | Viewed by 7480 | Submission Open
Keywords: functional foods; bioactive compounds; antioxidants; anti-inflammatory; nutraceuticals; isolation of bioactives; interactions of bioactives; food matrix; bioaccessibility; bioavailability
(This special issue belongs to the Section Food Chemistry)
Bioactive Properties and Chemical Composition of Wild Edible Species, 2nd Edition
edited by Spyridon Petropoulos
submission deadline 31 Oct 2026 | 5 articles | Viewed by 6369 | Submission Open
Keywords: wild edible species; bioactive properties; polyphenols; antioxidant activity; antimicrobial properties; carotenoids; vitamins
(This special issue belongs to the Section Natural Products Chemistry)
NMR and MRI in Materials Analysis: Opportunities and Challenges
edited by
submission deadline 31 Oct 2026 | 6 articles | Viewed by 6120 | Submission Open
Keywords: molecular dynamics and transport phenomena in polymers; hardening reactions in materials; magnetic resonance in analysis of pharmaceutical products; contrast agents; chemistry of wood and its products; thermal and other types of processing of foods; electrochemistry and transport phenomena in batteries and other energy storage devices
Natural Products with Pharmaceutical Activities, 2nd Edition
edited by and
submission deadline 31 Oct 2026 | 4 articles | Viewed by 6118 | Submission Open
Keywords: bioactive compounds; drug discovery; natural product chemistry; pharmacological evaluation; structure–activity relationship
(This special issue belongs to the Section Natural Products Chemistry)
Catalytic Materials for Energy and Environment: Preparation, Properties and Applications
edited by and Yanfei Xu
submission deadline 31 Oct 2026 | 3 articles | Viewed by 5370 | Submission Open
Keywords: biomass conversion; CO2 hydrogenation; plastic degradation; alkane dehydrogenation; syngas conversion; methane reforming; catalysts for energy and environment; catalytic mechanism
(This special issue belongs to the Section Materials Chemistry)
Nanochemistry in Asia
edited by Lei Huang and
submission deadline 31 Oct 2026 | 5 articles | Viewed by 5034 | Submission Open
Keywords: nanochemistry; nanomaterials; nanomedicine; nanotoxicity; nanocatalysis
(This special issue belongs to the Section Nanochemistry)
Plant Metabolites: Isolation, Phytochemistry, and Biological Activities
edited by , Karolina Grabowska and
submission deadline 31 Oct 2026 | 3 articles | Viewed by 4642 | Submission Open
Keywords: isolation; plant metabolites; plant extracts; medicinal plants; biological activity assessment
(This special issue belongs to the Section Natural Products Chemistry)
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