Review Papers in Inorganic Chemistry
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Inorganic Chemistry".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 121
Special Issue Editor
Interests: bioinorganic chemistry; complexes; antitumor; antimicrobial; structural characterization; spectral data
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Although inorganic chemistry is considered an 'old lady' in the field of science, it continues to surprise with its rate of expansion and variety of valuable species reported annually. The field comprises a wide range of species, from simple compounds such as alloys, salts, and oxides, to coordinative species such as complexes and organometallic compounds, and finally hybrid materials.
The controlled design of these species provides a versatile platform for developing high-performance materials. Particular attention is paid to designing and developing metallodrugs and inorganic carriers for organic and inorganic species.
As a result, in the post-cisplatin era, there has been a surge in the development of coordination compounds as biologically active species. The demand for these compounds stems from the need for new drugs and/or optimised formulations to effectively treat various diseases, including cancers, diabetes mellitus, inflammation, and viral, microbial and parasitic infections. For several of these diseases, metallodrugs have proven to be more effective than organic species. This behaviour is due to the different target biomolecules and mechanisms of action that are characteristic of inorganic species. When interacting with biomolecules, metal ions form coordinative bonds and subsequently mediate their splitting through redox processes. Additionally, selective interactions can be achieved by selecting the appropriate metal ions and ligands.
As a result, several coordination compounds based on both essential (V, Cr, Mn, Fe, Cu, and Zn) and non-essential (Pt, Ru, Au, Ag, Bi, Sn, and Ti) metal ions have been synthesised and characterised for this purpose, with the aim of creating a sustainable platform for future metallodrug development. Beyond the therapeutic aspect, such species must be low in toxicity and easy to administer. Therefore, future research must focus on designing and evaluating new inorganic species and hybrid systems with favourable biological properties.
Dr. Rodica Olar
Guest Editor
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Keywords
- coordinative compounds
- metallodrug
- biological activity
- target biomolecule
- essential ion
- carrier
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