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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Carbon-Based Materials for Sustainable Chemistry: 3rd Edition
edited by
submission deadline 31 May 2026 | Viewed by 70 | Submission Open
Keywords: carbon-based materials; carbon nanostructures; adsorption; sustainability
(This special issue belongs to the Section Materials Chemistry)
Heterocycles: Design, Synthesis and Biological Evaluation, 4th Edition submission deadline 31 May 2026 | Viewed by 68 | Submission Open
Keywords: heterocycles; organic synthesis; drug design; biological activity; medicinal chemistry
(This special issue belongs to the Section Medicinal Chemistry)
Therapeutic Potential of Bioactive Dietary Small Molecules and Natural Products: From Discovery to Mechanistic Understanding submission deadline 31 May 2026 | Viewed by 66 | Submission Open
Keywords: bioactive compounds; natural products; dietary small molecules; therapeutic agents; mechanism of action; nutraceuticals; functional foods; molecular targets; pharmacological activity; chronic diseases; anti-inflammatory; antioxidant; metabolic disorders; hormone-related diseases
(This special issue belongs to the Section Food Chemistry)
Advances in Biomass Conversion, Biofuel Production and Biorefinery Processes submission deadline 31 May 2026 | Viewed by 62 | Submission Open
Keywords: biomass conversion; biofuels; catalysis; biorefinery integration; CO2 utilization; hydrogen production; energy storage; life-cycle and techno-economic analysis
(This special issue belongs to the Section Green Chemistry)
Environmental Analysis of Organic Pollutants, 3rd Edition
edited by
submission deadline 31 May 2026 | Viewed by 55 | Submission Open
Keywords: organic pollutants; persistent organic pollutants; emerging contaminants; new pollutants; air; water; soil and sediment; emission; environmental fate; transformation; target analysis and non-target analysis
(This special issue belongs to the Section Green Chemistry)
Review Papers in Physical Chemistry
edited by
submission deadline 31 May 2026 | Viewed by 52 | Submission Open
Keywords: physical chemistry; spectroscopy; quantum chemistry; surface chemistry; molecular dynamics simulations  
(This special issue belongs to the Section Physical Chemistry)
Bioactive Peptides: Isolation, Identification and Application submission deadline 31 May 2026 | Viewed by 49 | Submission Open
Keywords: peptides; proteins; hydrolysis; bioavailability; application; biological activity; food technology
(This special issue belongs to the Section Food Chemistry)
New Synthetic Drugs of Abuse submission deadline 31 May 2026 | Viewed by 45 | Submission Open
Keywords: new psychoactive substances (NPS); structure– activity relationships; pharmacokinetics and pharmacodynamics; toxicological mechanisms; advanced analytical methodologies; biomarkers of exposure
(This special issue belongs to the Section Medicinal Chemistry)
Application of Polyacrylonitrile in Catalytic Conversion and Environmental Remediation
edited by
submission deadline 31 May 2026 | Viewed by 44 | Submission Open
Keywords: polyacrylonitrile (PAN); environmental remediation; catalytic conversion; functionalized composites
(This special issue belongs to the Section Macromolecular Chemistry)
Algal Biomolecules for Food and Pharmaceutical Innovations: Extraction, Characterization and Applications
edited by Renu Geetha Bai
submission deadline 31 May 2026 | Viewed by 40 | Submission Open
Keywords: algal biotechnology; biomass valorization; bioavailability evaluations; advanced extraction and purification techniques; functional and nutraceutical properties
(This special issue belongs to the Section Natural Products Chemistry)
Small Molecules in Molecular Imaging, Chemical Biology and Drug Discovery
edited by
submission deadline 31 May 2026 | Viewed by 38 | Submission Open
Keywords: small molecules; molecular design and synthesis; molecular imaging; chemical biology; drug discovery; biomarker visualization; therapeutic targeting; translational medicine; disease mechanisms; personalized diagnostics; biomedical innovation
(This special issue belongs to the Section Medicinal Chemistry)
Photoactive Compounds: From Dye Design to Advanced Probes and Photosensitizers
edited by Janina Kabatc-Borcz
submission deadline 31 May 2026 | Viewed by 34 | Submission Open
Keywords: photosensitizer; initiator; photosensitive materials; probes; dye
(This special issue belongs to the Section Photochemistry)
Flexible Materials and Devices for Human Health
edited by Ding Zhang
submission deadline 31 May 2026 | Viewed by 33 | Submission Open
Keywords: flexible materials and devices; self-powered sensing; energy conversion; health monitoring; disease treatment
(This special issue belongs to the Section Applied Chemistry)
Metal–Organic Cages: Synthesis and Applications
edited by Simona Nica
submission deadline 31 May 2026 | Viewed by 33 | Submission Open
Keywords: synthetic strategies; self-assembly processes; crystal engineering; computational studies; post-synthetic functionalization
(This special issue belongs to the Section Organic Chemistry)
Advanced Fluorescent Probes for Bioimaging and Environmental Sensing
edited by
submission deadline 31 May 2026 | Viewed by 33 | Submission Open
Keywords: metal ions; anions; phosphates; fluorescence; aldehydes; phosphorescence; sensitive detection; analytical methods
(This special issue belongs to the Section Analytical Chemistry)
Recent Advances in Circularly Polarized Luminescence Materials
edited by and Biao Zhao
submission deadline 31 May 2026 | Viewed by 29 | Submission Open
Keywords: circularly polarized luminescence; chirality; small molecules; polymers; chiral liquid crystals; self-assembled materials; optoelectronics; information security
(This special issue belongs to the Section Materials Chemistry)
Current Research in Wine Chemistry and Analysis submission deadline 31 May 2026 | Viewed by 26 | Submission Open
Keywords: wine chemistry; analytical methods; sensory properties; phenolic compounds; fermentation chemistry
(This special issue belongs to the Section Food Chemistry)
Chitosan-Based Materials for Pharmaceutical and Medical Applications submission deadline 31 May 2026 | Viewed by 25 | Submission Open
Keywords: chitin; chitosan; chitosan modification; chitosan-based drug delivery systems; chitosan nanoparticles; chitosan for biomedical use; chitosan biomaterials  
(This special issue belongs to the Section Materials Chemistry)
Small Fish Models for Molecular-Ethnopharmacology and Drug Discovery
edited by
submission deadline 31 May 2026 | Viewed by 21 | Submission Open
Keywords: bioactive compounds; chemical biology; natural product screening; omics; phytochemicals; systems pharmacology
(This special issue belongs to the Section Medicinal Chemistry)
Advanced Membrane Materials for Water Treatment
edited by
submission deadline 31 May 2026 | Viewed by 21 | Submission Open
Keywords: advanced membranes; water treatment; membrane materials; nanocomposites; desalination; wastewater reuse; antifouling; mixed-matrix membranes (MMMs); emerging contaminants; membrane fabrication
(This special issue belongs to the Section Green Chemistry)
Wide-Bandgap (WBG) Semiconductors: Advancements in Synthesis, Surface Engineering, and Applications
edited by
submission deadline 31 May 2026 | Viewed by 19 | Submission Open
Keywords: wide-bandgap semiconductors; gallium oxide; Ga2O3; diamond; aluminum nitride; AlN; surface engineering; semiconductor devices
(This special issue belongs to the Section Applied Chemistry)
Analytical Methods for Food and Environmental Pollutants: Current and Future Perspectives, 2nd Edition submission deadline 31 May 2026 | Viewed by 18 | Submission Open
Keywords: emerging pollutants; food samples; environmental samples; sampling; sample preparation; analytical instrumentation; chemometric tools
(This special issue belongs to the Section Analytical Chemistry)
Porous and Nanoporous Materials in Heterogeneous Catalysis, 2nd Edition
edited by Angela Martins
submission deadline 31 May 2026 | Viewed by 18 | Submission Open
Keywords: porous and nanoporous materials; heterogeneous catalysts; hierarchical materials; bifunctional catalysts; catalyst supports; zeolites; zeotypes; carbon materials; MOFs; mesoporous silicas
(This special issue belongs to the Section Materials Chemistry)
Bioactive and Nutritional Molecules: From Natural Sources to Therapeutic and Health Applications, 2nd Edition
edited by
submission deadline 31 May 2026 | Viewed by 13 | Submission Open
Keywords: bioactive and nutritional molecules; natural therapeutic agents; bioactive compounds
(This special issue belongs to the Section Cross-Field Chemistry)
Novel Drugs for Anticancer Therapy
edited by
submission deadline 31 May 2026 | Viewed by 13 | Submission Open
Keywords: anticancer activity; natural small molecules; anticancer drugs; synthetic analogues
(This special issue belongs to the Section Medicinal Chemistry)
Carriers, Channels, Receptors, and Enzymes: Protein Targets of New Synthetic and Natural Compounds, 2nd Edition submission deadline 31 May 2026 | Viewed by 9 | Submission Open
Keywords: carrier; channel; receptor; enzyme; drug design; synthesis; biological evaluation; inhibitors; bioactive compounds; cell metabolism; mitochondria; human pathology
(This special issue belongs to the Section Chemical Biology)
Acknowledged and Emerging Contaminants in Food and Natural Supplements
edited by
submission deadline 31 May 2026 | Submission Open
Keywords: food authentication; contaminants; toxicity; risk assessment; molecular fingerprint; metabolomics; AI-based omics; consumer safety
(This special issue belongs to the Section Analytical Chemistry)
Novel Functional Nanomaterials for Sensing and Biomedical Applications
edited by
submission deadline 1 Jun 2026 | Viewed by 80 | Submission Open
Keywords: functional nanomaterials; biosensing; chemical sensing; drug delivery; bioimaging; theranostics; nanobiotechnology; nanosensors; nanomedicine
Innovative Technologies for Food Processing and Preservation submission deadline 1 Jun 2026 | Viewed by 34 | Submission Open
Keywords: innovative food processing technologies; food preservation; food safety and quality; food sustainability; shelf-life extension; microbial inactivation; bioactive compounds
(This special issue belongs to the Section Food Chemistry)
Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition: 3rd Edition submission deadline 15 Jun 2026 | 3 articles | Viewed by 3188 | Submission Open
Keywords: enantioselective synthesis; enantioseparation; chiral analyses; chiral recognition; chiral sensors
Advanced Technologies for Water Pollution Control
edited by and
submission deadline 15 Jun 2026 | Viewed by 49 | Submission Open
Keywords: water pollution; advanced oxidation processes; membrane technologies; nanotechnology application; wastewater remediation; advanced technologies
(This special issue belongs to the Section Green Chemistry)
Metal Recovery from Waste Polymetallic Materials
edited by Ewa Rudnik
submission deadline 15 Jun 2026 | Viewed by 20 | Submission Open
Keywords: extractive metallurgy; hydrometallurgy; solvometallurgy; leaching; ion separation; metal recovery; industrial waste; recycling
(This special issue belongs to the Section Green Chemistry)
Advanced Photo/Electrocatalysts for Energy Conversion and Environmental Applications, 3rd Edition
edited by and Dengrong Sun
submission deadline 15 Jun 2026 | Viewed by 10 | Submission Open
Keywords: photocatalyst; electrocatalysis; nanostructured materials; surface/interface regulation; environment; energy
(This special issue belongs to the Section Photochemistry)
Biosynthetic Strategies for Exploiting Natural Products: Recent Advances and Applications
edited by and
submission deadline 15 Jun 2026 | Viewed by 9 | Submission Open
Keywords: biosynthetic gene clusters; genome mining; heterologous expression; pathway elucidation; metabolic engineering
(This special issue belongs to the Section Natural Products Chemistry)
Molecular Design and Functional Materials for Food Packaging Applications submission deadline 16 Jun 2026 | Viewed by 19 | Submission Open
Keywords: packaging applications; functionality; active agents; coatings; processed films; advanced technologies
(This special issue belongs to the Section Food Chemistry)
Green Catalysis Technology for Sustainable Energy Conversion submission deadline 30 Jun 2026 | 10 articles | Viewed by 13498 | Submission Open
Keywords: catalysis; sustainable energy; energy crisis; environmental pollution
(This special issue belongs to the Section Green Chemistry)
Advances in Physicochemical Properties of Innovative Food Products During Processing submission deadline 30 Jun 2026 | 6 articles | Viewed by 6837 | Submission Open
Keywords: innovative food processing; pulsed electric fields; ultrasound processing; cold plasma; hybrid drying; fermentation; physicochemical properties; functional and sensory attributes; natural ingredients; food structure and stability; nutritional value; sustainable food systems
(This special issue belongs to the Section Food Chemistry)
Aromatic Heterocyclic Compounds: Synthesis, Reactivity and Applications
edited by
submission deadline 30 Jun 2026 | 2 articles | Viewed by 4331 | Submission Open
Keywords: aromatic heterocycles with one heteroatom; aromatic heterocycles with two or more heteroatoms; condensed compounds containing an aromatic heterocycle; direct synthesis; synthesis using electrophilic or nucleophilic reactions; metalation and reactivity; applications of aromatic heterocyclic compounds
(This special issue belongs to the Section Organic Chemistry)
Porous Polymers Design, Synthesis and Applications in the Field of Catalysis, Separation and Energy
edited by and
submission deadline 30 Jun 2026 | 2 articles | Viewed by 3612 | Submission Open
Keywords: polymers design and synthesis; pore structure; morphology; surface modification; physical characteristics; mechanical properties; catalysis; thermal stability; transport; separation; advanced techniques
(This special issue belongs to the Section Materials Chemistry)
30th Anniversary of Molecules: Recent Advances in Photochemistry submission deadline 30 Jun 2026 | 3 articles | Viewed by 2659 | Submission Open
Keywords: organic photochemistry synthetic photochemistry; photocatalysis; photofunctionalization; photobiology; medicinal photochemistry; computational photochemistry; photoelectrochemistry; solar energy conversion; condensed and gas phase photochemistry; polymer photochemistry; supramolecular photochemistry; photochromism; luminescent sensors; photochemistry for environmental remediation
(This special issue belongs to the Section Photochemistry)
Inorganic Chemistry in Asia, 2nd Edition
edited by
submission deadline 30 Jun 2026 | 2 articles | Viewed by 1397 | Submission Open
Keywords: inorganic chemistry; coordination chemistry; organometallic chemistry; solid-state chemistry; bioinorganic chemistry; nuclear- and radiochemistry; theoretical calculation
(This special issue belongs to the Section Inorganic Chemistry)
New Insights into High Performance Carbon-Based Electrode Materials
edited by and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1347 | Submission Open
Keywords: carbon materials; energy storage and conversion; battery; supercapacitor; electrode material
(This special issue belongs to the Section Electrochemistry)
Biological Activity and Chemical Composition of Honeybee Products
edited by and Alexandra Christine Helena F. Sawaya
submission deadline 30 Jun 2026 | 2 articles | Viewed by 1291 | Submission Open
Keywords: chemical composition; biological activity; products from native bees; regulation; quality control
(This special issue belongs to the Section Natural Products Chemistry)
Discovery, Isolation, and Mechanisms of Bioactive Natural Products (2nd Edition)
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 935 | Submission Open
Keywords: natural products; bioactivities; structural elucidation; mechanisms
(This special issue belongs to the Section Natural Products Chemistry)
Advancement in Phytochemistry and Pharmacology of Medicinal Plants
edited by and Claúdia Quintino Da Rocha
submission deadline 30 Jun 2026 | 1 articles | Viewed by 934 | Submission Open
Keywords: green chemistry and sustainable chemical processes; advanced thin layer chromatography; ethical application of artificial intelligence in natural products; natural product platforms; pharmaceutical biotechnology and chemical innovation; bioprospecting; phytomedicine; in vivo and in vitro ethnopharmacological studies; promising chemical– biological studies by research groups; phytomedicine and chemical standardization of herbal formulations
(This special issue belongs to the Section Natural Products Chemistry)
Plant Secondary Metabolites: Extraction, Isolation and Biological Activity submission deadline 30 Jun 2026 | 1 articles | Viewed by 916 | Submission Open
Keywords: secondary metabolites; extraction; chromatography; identification (NMR; MS; etc.); hyphenated techniques (Gc-MS; LC-MS; etc.); biological activity; structure– activity relationships; mechanism of action
(This special issue belongs to the Section Natural Products Chemistry)
Crystal and Molecular Structure: Theory and Application submission deadline 30 Jun 2026 | 1 articles | Viewed by 839 | Submission Open
Keywords: crystal structure; molecular structure; DFT; structural analysis; molecular modeling; calculations; physicochemical analysis; polymorphism
(This special issue belongs to the Section Applied Chemistry)
Redox-Active Molecules as Key Players for Inflammatory Diseases
edited by Ange Mouithys-Mickalad
submission deadline 30 Jun 2026 | Viewed by 818 | Submission Open
Keywords: redox-active Molecules; oxidative stress; inflammatory diseases; QSAR; computer-aided drug design; redox active natural compounds
(This special issue belongs to the Section Medicinal Chemistry)
Applications of Radiochemistry in Healthcare
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 704 | Submission Open
Keywords: radiochemistry; radioligand therapy; radiolabeled antibodies; nanobodies; radionuclides
(This special issue belongs to the Section Medicinal Chemistry)
New Insights into Protein and Biomolecule Interactions
edited by Xin Peng and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 543 | Submission Open
Keywords: protein; biomolecule; interaction; protein-biomolecule interactions; structural insights; drug development
(This special issue belongs to the Section Bioorganic Chemistry)
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