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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Biocatalytic Platforms Towards Synthesis and Degradation Processes submission deadline 28 Feb 2026 | 1 articles | Viewed by 780 | Submission Open
Keywords: biotechnology; bioconversions; biodegradations; green chemistry
(This special issue belongs to the Section Bioorganic Chemistry)
Nutritional Properties, Sensory Profile and Bioactive Components of Food, 3rd Edition submission deadline 28 Feb 2026 | 2 articles | Viewed by 581 | Submission Open
Keywords: food analysis; bioactive compounds; sensory characteristics; food composition; functional food ingredients
(This special issue belongs to the Section Food Chemistry)
Advanced Photocatalysts for Environmental Remediation and Contaminant Removal
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 568 | Submission Open
Keywords: nonbiodegradable organic contaminants; antibiotic contaminants; dye contaminants; pesticide pollutants; photocatalytic degradation; advanced photocatalysts; oxidic radicals; degradation pathways; degradation mechanism; photophysical property; photochemical property
(This special issue belongs to the Section Applied Chemistry)
Recent Advances in DNA/Protein Biosensors submission deadline 28 Feb 2026 | 1 articles | Viewed by 564 | Submission Open
Keywords: biosensors; DNA; RNA; proteins; biomarkers
(This special issue belongs to the Section Analytical Chemistry)
Natural Dyes for the Textile and Leather Industries—for the Future’s Sustainability submission deadline 28 Feb 2026 | Viewed by 364 | Submission Open
Keywords: natural dyes; textile and leather industries; extraction methodologies; pigment characterization; new dye to fiber binding agents and strategies; bioactive properties; industrial applications
(This special issue belongs to the Section Colorants)
Recent Advances in Fluorescent Probes: Design, Synthesis, Properties and Application
edited by Zhaoyang Wang and Yancheng Wu
submission deadline 28 Feb 2026 | Viewed by 291 | Submission Open
Keywords: fluorescent probes; fluorescent sensors; fluorescent analytical technology; chemical detection; biological detection; fluorescence
(This special issue belongs to the Section Photochemistry)
Research Advances in Li-Ion Battery Materials: Present and Future
edited by
submission deadline 28 Feb 2026 | Viewed by 273 | Submission Open
Keywords: lithium-ion battery; anode materials; cathode materials; characterization
(This special issue belongs to the Section Applied Chemistry)
Visible Light Active Photocatalysts for Organic Synthesis
edited by Wentao Xu
submission deadline 28 Feb 2026 | Viewed by 237 | Submission Open
Keywords: organic chemistry; photocatalyst; synthesis; radical; single-electron transfer; atom transfer; energy transfer
(This special issue belongs to the Section Organic Chemistry)
Hierarchical Organization in Polymeric and Amphiphilic Self-Assembly
edited by Thi Vo
submission deadline 28 Feb 2026 | Viewed by 227 | Submission Open
Keywords: self-assembly; amphiphile; polymers; computational modeling; synthesis; material design
(This special issue belongs to the Section Macromolecular Chemistry)
Anti-Cancer and Anti-Inflammatory Activity of Medicinal Plants
edited by
submission deadline 28 Feb 2026 | Viewed by 223 | Submission Open
Keywords: medicinal plants; anti-cancer activity; anti-inflammatory activity; natural products; modification; derivatives; bioassay
(This special issue belongs to the Section Medicinal Chemistry)
Advances in Radiation Detection Materials and Technology
edited by Qianli Li and Weiguang Yang
submission deadline 28 Feb 2026 | Viewed by 221 | Submission Open
Keywords: radiation-sensitive material; scintillation material; luminescent center optimization; radiation detection materials; flexible dosimeter; semiconductor heterostructure engineering; synthesis; characterization; application; determination of the crystal structure of biomacromolecules
Heterocyclic Bioactive Molecules: Structural Analysis and Innovative Applications in Medicinal Chemistry submission deadline 28 Feb 2026 | Viewed by 200 | Submission Open
Keywords: heterocyclic compounds; drug design; AI machine learning; bioorthogonal chemistry; molecular imaging; small-molecule probes; PROTAC
(This special issue belongs to the Section Medicinal Chemistry)
Computational Chemistry in Homogeneous and Heterogeneous Catalysis and Surface Chemistry
edited by Haya Kornweitz and
submission deadline 28 Feb 2026 | Viewed by 192 | Submission Open
Keywords: density functional theory (DFT); heterogeneous catalysis; homogeneous catalysis; surface reactions; reaction mechanism; metallic Surfaces; nanoparticles; adsorption; desorption; ab initio calculations; material science; surface modelling; reaction kinetics; thermochemistry and reactivity; transition State theory; potential energy surfaces (PES); hydrogenation; hydrogen evolution reaction (HER); oxygen evolution reaction (OER); CO2 reduction; electrocatalysis; machine learning
Secondary Metabolites: Green Isolation, AI-Assisted Elucidation, and Mechanistic Insight
edited by Niko Radulović and
submission deadline 28 Feb 2026 | Viewed by 170 | Submission Open
Keywords: secondary metabolites; natural products; AI/ML dereplication; metabolomics; advanced NMR/MS; green/flow isolation; chemoproteomics; mechanism of action; FAIR data
(This special issue belongs to the Section Natural Products Chemistry)
Theme Issue in Honor to Prof. Dr. Douglas Stephan’ Great Achievement in Inorganic Chemistry
edited by Meera Mehta and Andrew Jupp
submission deadline 28 Feb 2026 | Viewed by 165 | Submission Open
Keywords: inorganic chemistry; catalysis; complexes
Synthesis and Characterization of Functional Materials for Electrochemical Energy Storage and Conversion—2nd Edition
edited by Feifei Wang
submission deadline 28 Feb 2026 | Viewed by 163 | Submission Open
Keywords: energy storage and conversion; electrochemical systems; batteries; hydrogen; supercapacitors; CO2 conversion
Complexes as Tool for Design and Synthesis of Species with Biological Application
edited by
submission deadline 28 Feb 2026 | Viewed by 162 | Submission Open
Keywords: metal complex; resistance; biofilm; antitumor; carrier; target biomolecule; drug design; hybrid material
(This special issue belongs to the Section Medicinal Chemistry)
Harnessing Peptides and Peptidomimetics in Modern Drug Discovery
edited by
submission deadline 28 Feb 2026 | Viewed by 159 | Submission Open
Keywords: peptide synthesis; peptidomimetics; cyclic peptides; peptide therapeutics; peptide drug discovery; modified peptides; bioactive peptides
(This special issue belongs to the Section Medicinal Chemistry)
Chemistry of Amino Acids, Peptides, and Proteins
edited by and Nicholas Truex
submission deadline 28 Feb 2026 | Viewed by 156 | Submission Open
Keywords: amino acids; peptides; proteins; synthesis; derivatives; characterization; structural studies; biophysical properties; natural products
(This special issue belongs to the Section Macromolecular Chemistry)
Oxidative Stress and Antioxidants in Degenerative Conditions
edited by Eleni A. Rekka and
submission deadline 28 Feb 2026 | Viewed by 150 | Submission Open
Keywords: antioxidants; oxidative stress; chronic-degenerative diseases; hormonal imbalance; anti-inflammatory activity; multi-targeting compounds
(This special issue belongs to the Section Medicinal Chemistry)
Fluorescent Sensing in Food and Environmental Detection submission deadline 28 Feb 2026 | Viewed by 147 | Submission Open
Keywords: environmental pollutants; food contaminants; organic residues; heavy metals; fluorescent sensing; fluorescent materials; food analysis; food quality; pollutant monitoring; food safety
(This special issue belongs to the Section Analytical Chemistry)
Chemical Biology in Europe submission deadline 28 Feb 2026 | Viewed by 138 | Submission Open
Keywords: chemical probes; bioorthogonal chemistry; chemical proteomics; target identification; probe-based visualization; PTM detection
(This special issue belongs to the Section Chemical Biology)
Metal Ions and Metal Complexes in Medicinal Chemistry submission deadline 28 Feb 2026 | Viewed by 138 | Submission Open
Keywords: metal ions; metal complexes; synthesis; study; spectral analysis; biological activity; ligands
(This special issue belongs to the Section Medicinal Chemistry)
Advances in Chemical Analysis Procedures (Part III): Future Trends in Reducing the Environmental Impact submission deadline 28 Feb 2026 | Viewed by 137 | Submission Open
Keywords: green approaches; analytical chemistry; instrumental analysis; sample preparation; quantitative analysis; AI; tools; metrics
(This special issue belongs to the Section Analytical Chemistry)
Chiral Nanomaterials: Synthesis, Properties, and Applications
edited by
submission deadline 28 Feb 2026 | Viewed by 133 | Submission Open
Keywords: chiral nanomaterial; property; synthesis; application
(This special issue belongs to the Section Applied Chemistry)
Current Topics and Applications of Chiral Auxiliaries
edited by Shawn Raynard Hitchcock
submission deadline 28 Feb 2026 | Viewed by 132 | Submission Open
Keywords: chiral auxiliary; asymmetric synthesis; diastereoselection; organic synthesis; stereochemistry; chiral control
(This special issue belongs to the Section Organic Chemistry)
Synthesis of Natural Compounds and Derivatives
edited by Fanie van Heerden and Mamoalosi Selepe
submission deadline 28 Feb 2026 | Viewed by 127 | Submission Open
Keywords: natural compounds; synthesis; total synthesis; semi-synthesis; derivatives
(This special issue belongs to the Section Natural Products Chemistry)
Recent Advances in Radical Chemistry
edited by and Ying Cheng
submission deadline 28 Feb 2026 | Viewed by 124 | Submission Open
Keywords: radical chemistry; radical cross-coupling; photocatalysis; electrochemical synthesis; transition metal catalysis
(This special issue belongs to the Section Organic Chemistry)
Bioactive Molecules for Targeted Cancer Therapy
edited by and Robert A. Falconer
submission deadline 28 Feb 2026 | Viewed by 122 | Submission Open
Keywords: enzymatic inhibitors; fragment-based discovery; chemical biology; covalent ligands; payloads; prodrug; (poly)peptide conjugates; antibody– drug conjugates; computational chemistry
(This special issue belongs to the Section Medicinal Chemistry)
Plant Bioactive Compounds in Pharmaceuticals, 2nd Edition submission deadline 28 Feb 2026 | Viewed by 122 | Submission Open
Keywords: bioactive compounds; medicinal plant; phytocomplexes; cell cultures
(This special issue belongs to the Section Natural Products Chemistry)
Nitrogen Containing Heterocyclic Scaffolds: Synthesis and Bioactivity
edited by and
submission deadline 28 Feb 2026 | Viewed by 118 | Submission Open
Keywords: heterocycles; heteroaromatics; drug discovery; organic synthesis; structure-activity relationship
(This special issue belongs to the Section Medicinal Chemistry)
Photocatalytic Water Splitting: Cutting-Edge Research and Future Directions
edited by
submission deadline 28 Feb 2026 | Viewed by 117 | Submission Open
Keywords: photocatalytic water splitting; hydrogen production; photocatalysts; heterojunctions; co-catalysts; charge carrier
(This special issue belongs to the Section Photochemistry)
Chemical Analyses and Applications of Essential Oils—2nd Edition
edited by
submission deadline 28 Feb 2026 | Viewed by 114 | Submission Open
Keywords: essential oils; bioactive compounds; liquid phase; vapor phase; potential applications
(This special issue belongs to the Section Natural Products Chemistry)
Biodegradable Polymers in Biological Application submission deadline 28 Feb 2026 | Viewed by 108 | Submission Open
Keywords: natural polymers; synthetic polymers; controlled degradation; compositional and structural modifications; processing
(This special issue belongs to the Section Macromolecular Chemistry)
Advancements on Field Detection Based on Nucleic Acid Amplification
edited by Xiong Xiong, and
submission deadline 28 Feb 2026 | Viewed by 107 | Submission Open
Keywords: nucleic acid; isothermal amplification; visual detection; colorimetric detection; fluorescence-based detection; point-of-care test; field detection
(This special issue belongs to the Section Analytical Chemistry)
Green Organic Synthesis: Innovations for a Sustainable Future
edited by
submission deadline 28 Feb 2026 | Viewed by 100 | Submission Open
Keywords: sustainability; organic synthesis; green chemistry; precise synthesis; chemoselectivity; regioselectivity; enantioselectivity; catalysis
(This special issue belongs to the Section Organic Chemistry)
Organometallic Compounds: Synthesis and Catalysis submission deadline 28 Feb 2026 | Viewed by 96 | Submission Open
Keywords: organometallic compounds; synthesis; catalysis; chemistry; structure
(This special issue belongs to the Section Organometallic Chemistry)
Heterocyclic Compounds and Their Metal Complexes as Potential Anticancer Drugs submission deadline 28 Feb 2026 | Viewed by 95 | Submission Open
Keywords: heterocyclic metal complexes; in vitro activity; anticancer activity; cell cycle; apoptosis; 3D cell culture
(This special issue belongs to the Section Medicinal Chemistry)
Advanced Nanostructured Materials for Electrochemical Energy Storage Devices
edited by and
submission deadline 28 Feb 2026 | Viewed by 91 | Submission Open
Keywords: electrochemical energy storage; supercapacitors; batteries; flow batteries; 2D transition metal carbides/nitride (MXene) nanomaterials; transition metal compounds; aqueous batteries; advanced nanostructured materials
(This special issue belongs to the Section Materials Chemistry)
Chemical Modifications and Interactions of Food Macromolecules: Mechanisms and Impacts on Quality
edited by Ling Liu and Yixiao Shen
submission deadline 28 Feb 2026 | Viewed by 89 | Submission Open
Keywords: lipid; protein; molecular interactions; food safety; food stability
(This special issue belongs to the Section Food Chemistry)
Green Conversion of Polymeric and Textile Waste into Functional Materials submission deadline 28 Feb 2026 | Viewed by 89 | Submission Open
Keywords: green chemistry; polymer conversion; textile waste valorization; plastic management; resource recovery; recycling; upcycling; functional materials
(This special issue belongs to the Section Green Chemistry)
Porous Carbon Materials: Preparation and Application, 2nd Edition
edited by
submission deadline 28 Feb 2026 | Viewed by 88 | Submission Open
Keywords: porous carbon materials; energy storage; environmental science; sensors; adsorption; catalysis
(This special issue belongs to the Section Applied Chemistry)
Recent Advances in Functionalized Nanomaterials: Design, Synthesis, Characterization, and Application—2nd Edition
edited by
submission deadline 28 Feb 2026 | Viewed by 82 | Submission Open
Keywords: functionalized nanomaterials; functionalized strategies; compositions; nanostructures; energy storage; sensing; environmental remediation; catalytic
(This special issue belongs to the Section Nanochemistry)
Theoretical, Computational and Experimental Advances on Molecular Optical Properties, 2nd Edition submission deadline 28 Feb 2026 | Viewed by 81 | Submission Open
Keywords: synthesis; theoretical computation; photophysical characterization; structure– propertyies relationship; bio-application; imaging
(This special issue belongs to the Section Physical Chemistry)
Emerging Trends in Two-Dimensional Materials: Synthesis, Properties and Applications
edited by Xiao Zhi
submission deadline 28 Feb 2026 | Viewed by 79 | Submission Open
Keywords: two-dimensional materials; biosensors; graphene; energy storage; catalysis; electronic conductivity
(This special issue belongs to the Section Materials Chemistry)
Advanced Electrocatalysts: Design, Characterization, and Applications in Sustainable Conversion Reactions
edited by Bruno Manzolli Rodrigues
submission deadline 28 Feb 2026 | Viewed by 78 | Submission Open
Keywords: electrocatalysis; nanostructured catalysts; atomically dispersed catalysis; sustainable catalysis; oxygen reduction reaction (ORR); oxygen evolution reaction (OER); CO2 reduction reaction (CO2RR); biomass conversion
(This special issue belongs to the Section Electrochemistry)
Synthesis and Properties of Heterocyclic Compounds: Recent Advances—2nd Edition submission deadline 28 Feb 2026 | Viewed by 71 | Submission Open
Keywords: heterocyclic compounds; synthesis; applications; biological activity
(This special issue belongs to the Section Organic Chemistry)
Recent Advances in Green and Enzymatic Catalysis for Synthesis of Functional Molecules
edited by
submission deadline 28 Feb 2026 | Viewed by 66 | Submission Open
Keywords: green catalysis; enzymatic synthesis; sustainable chemistry; biocatalysis; functional molecules
(This special issue belongs to the Section Bioorganic Chemistry)
Metal-Organic Framework-Derived Materials for High-Performance Ion Batteries
edited by and Wenting Li
submission deadline 28 Feb 2026 | Viewed by 66 | Submission Open
Keywords: metal– organic frameworks; MOF-derived materials; high-performance ion batteries; electrochemical performance; energy conversion; energy storage; nanoporous materials
(This special issue belongs to the Section Materials Chemistry)
Health Promoting Compounds in Milk and Dairy Products, 2nd Edition
edited by and
submission deadline 28 Feb 2026 | Viewed by 60 | Submission Open
Keywords: milk; dairy products; functional compounds; food quality; protein and bioactive peptides; minerals; vitamins; antioxidant compounds; promoting health and well-being
(This special issue belongs to the Section Food Chemistry)
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